Wilson, Shona, Booth, Mark, Jones, Frances M, Mwatha, Joseph K, Kimani, Gachuhi, Kariuki, H Curtis, ...
Abstract Background Amongst school-aged children living in malaria endemic areas, chronic morbidity and exacerbation of morbidity associated with other infections are often not coincident with the...
Booth, Mark, Vennervald, Birgitte J, Butterworth, Anthony E, Kariuki, Henry C, Amaganga, Clifford, Kimani, Gachuhi, ...
Abstract Background Schistosoma mansoni and malaria infections are often endemic in the same communities in sub-Saharan Africa, and both have pathological effects on the liver and the spleen....
Booth, Mark, Vennervald, Birgitte J, Kenty, LeeCarol, Butterworth, Anthony E, Kariuki, Henry C, Kadzo, Hilda, ...
Abstract Background Schistosoma mansoni and Plasmodium falciparum are common infections of school aged children in Kenya. They both cause enlargement of the spleen, but their relative contribution to...
Satti, Mohamed Z, Cahen, Pierre, Skov, Per S, Joseph, Sarah, Jones, Frances M, Fitzsimmons, Colin, ...
Abstract Background Parasite-specific IgE levels correlate with human resistance to reinfection with Schistosoma spp . after chemotherapy. Although the role of eosinophils in schistosomiasis has been...
Characterization of the Schistosomatranscriptome opens up the world of helminth genomics (2003)
Hoffmann, Karl F, Dunne, David W
Abstract Among the metazoan parasites that cause debilitating disease in man, schistosomes are the first group for which near-complete transcriptome complements have been described. This new genomic...
Hoffmann, Karl F, Johnston, David A, Dunne, David W
Abstract Background Parasitic helminths of the genus Schistosoma mate, achieve sexual maturity and produce eggs in the bloodstream of their definitive hosts, and the most important pathological...
Fallon, Padraic G., Smith, Philip, Richardson, Emma J., Jones, Frances J., Faulkner, Helen C., Van Snick, Jacques, ...
Mice infected with Schistosoma mansoni develop Th2 cytokine-mediated granulomatous pathology that is focused on the liver and intestines. In this study, transgenic mice constitutively expressing IL-9...
Naus, Cynthia W. A., Kimani, Gachuhi, Ouma, John H., Fulford, Anthony J. C., Webster, Michelle, Van Dam, Govert J., ...
We have identified the influence of host and parasite factors that give rise to characteristic antibody isotype profiles with age seen in human populations living in different areas of...
Dehydroepiandrosterone Sulfate Treatment of Mice Modulates Infection with Schistosoma mansoni
Fallon, Padraic G., Richardson, Emma J., Jones, Frances M., Dunne, David W.
Female mice treated with dehydroepiandrosterone sulfate early during infection were partially protected (P < 0.05–0.005) from Schistosoma mansoni infection. Hormone treatment did not modify...
Hoffmann, Karl F, Johnston, David A, Dunne, David W
Using cDNA microarray technology 12 new female-associated and 4 new male-associated gene transcripts were identified in mature adult Schistosoma mansoni parasites.
Naus, Cynthia W. A., Van Remoortere, Alexandra, Ouma, John H., Kimani, Gachuhi, Dunne, David W., Kamerling, Johannis P., ...
By the use of surface plasmon resonance spectroscopy, immunoglobulin G (IgG) subclass and IgM antibodies against three schistosome-derived carbohydrate structures, FLDN...
Joseph, Sarah, Jones, Frances M., Kimani, Gachuhi, Mwatha, Joseph K., Kamau, Timothy, Kazibwe, Francis, ...
The human host is continuously exposed to the egg and the adult worm developmental stages of Schistosoma mansoni during chronic infections with the parasite. To assess the cytokine responses induced...
Mentink-Kane, Margaret M., Cheever, Allen W., Thompson, Robert W., Hari, Danielle M., Kabatereine, Narcis B., Vennervald, Birgitte J., ...
An important feature of many chronic parasitic infections is the ability of the invading pathogen and host to establish a compromise, which ensures successful parasitism without killing the infected...
Characterization of the Schistosoma transcriptome opens up the world of helminth genomics
Hoffmann, Karl F, Dunne, David W
Among the metazoan parasites that cause debilitating disease in man, schistosomes are the first group for which near-complete transcriptome complements have been described. This new genomic...
Satti, Mohamed Z, Cahen, Pierre, Skov, Per S, Joseph, Sarah, Jones, Frances M, Fitzsimmons, Colin, ...
Booth, Mark, Vennervald, Birgitte J, Kenty, LeeCarol, Butterworth, Anthony E, Kariuki, Henry C, Kadzo, Hilda, ...
Fitzsimmons, Colin M., Joseph, Sarah, Jones, Frances M., Reimert, Claus M., Hoffmann, Karl F., Kazibwe, Francis, ...
Chemotherapy for blood-dwelling schistosomes kills the worms and exposes parasite antigen to the circulation. In many people from areas of endemicity, this treatment increases parasite-specific...
Booth, Mark, Vennervald, Birgitte J, Butterworth, Anthony E, Kariuki, Henry C, Amaganga, Clifford, Kimani, Gachuhi, ...
Reimert, Claus M., Fitzsimmons, Colin M., Joseph, Sarah, Mwatha, Joseph K., Jones, Frances M., Kimani, Gachuhi, ...
Eosinophil activity in vivo and in vitro was studied in relation to infection intensities and plasma cytokine profiles of 51 Schistosoma mansoni-infected Ugandan fishermen before treatment and 24 h...
Pierrot, Christine, Wilson, Shona, Lallet, Hélène, Lafitte, Sophia, Jones, Frances M., Daher, Wassim, ...
Plasmodium falciparum and Schistosoma mansoni are often found in human coinfections, and cross-reactive antibodies to different components of the two parasites have been detected. In this work, we...
Fallon, Padraic G., Smith, Philip, Richardson, Emma J., Jones, Frances J., Faulkner, Helen C., Van Snick, Jacques, ...
Mice infected with Schistosoma mansoni develop Th2 cytokine-mediated granulomatous pathology that is focused on the liver and intestines. In this study, transgenic mice constitutively expressing IL-9...
Naus, Cynthia W. A., Kimani, Gachuhi, Ouma, John H., Fulford, Anthony J. C., Webster, Michelle, Van Dam, Govert J., ...
We have identified the influence of host and parasite factors that give rise to characteristic antibody isotype profiles with age seen in human populations living in different areas of...
Dehydroepiandrosterone Sulfate Treatment of Mice Modulates Infection with Schistosoma mansoni
Fallon, Padraic G., Richardson, Emma J., Jones, Frances M., Dunne, David W.
Female mice treated with dehydroepiandrosterone sulfate early during infection were partially protected (P < 0.05–0.005) from Schistosoma mansoni infection. Hormone treatment did not modify...
Hoffmann, Karl F, Johnston, David A, Dunne, David W
Using cDNA microarray technology 12 new female-associated and 4 new male-associated gene transcripts were identified in mature adult Schistosoma mansoni parasites.
Naus, Cynthia W. A., Van Remoortere, Alexandra, Ouma, John H., Kimani, Gachuhi, Dunne, David W., Kamerling, Johannis P., ...
By the use of surface plasmon resonance spectroscopy, immunoglobulin G (IgG) subclass and IgM antibodies against three schistosome-derived carbohydrate structures, FLDN...
Joseph, Sarah, Jones, Frances M., Kimani, Gachuhi, Mwatha, Joseph K., Kamau, Timothy, Kazibwe, Francis, ...
The human host is continuously exposed to the egg and the adult worm developmental stages of Schistosoma mansoni during chronic infections with the parasite. To assess the cytokine responses induced...
Mentink-Kane, Margaret M., Cheever, Allen W., Thompson, Robert W., Hari, Danielle M., Kabatereine, Narcis B., Vennervald, Birgitte J., ...
An important feature of many chronic parasitic infections is the ability of the invading pathogen and host to establish a compromise, which ensures successful parasitism without killing the infected...
Characterization of the Schistosoma transcriptome opens up the world of helminth genomics
Hoffmann, Karl F, Dunne, David W
Among the metazoan parasites that cause debilitating disease in man, schistosomes are the first group for which near-complete transcriptome complements have been described. This new genomic...
Satti, Mohamed Z, Cahen, Pierre, Skov, Per S, Joseph, Sarah, Jones, Frances M, Fitzsimmons, Colin, ...
Booth, Mark, Vennervald, Birgitte J, Kenty, LeeCarol, Butterworth, Anthony E, Kariuki, Henry C, Kadzo, Hilda, ...
Fitzsimmons, Colin M., Joseph, Sarah, Jones, Frances M., Reimert, Claus M., Hoffmann, Karl F., Kazibwe, Francis, ...
Chemotherapy for blood-dwelling schistosomes kills the worms and exposes parasite antigen to the circulation. In many people from areas of endemicity, this treatment increases parasite-specific...
Booth, Mark, Vennervald, Birgitte J, Butterworth, Anthony E, Kariuki, Henry C, Amaganga, Clifford, Kimani, Gachuhi, ...
Reimert, Claus M., Fitzsimmons, Colin M., Joseph, Sarah, Mwatha, Joseph K., Jones, Frances M., Kimani, Gachuhi, ...
Eosinophil activity in vivo and in vitro was studied in relation to infection intensities and plasma cytokine profiles of 51 Schistosoma mansoni-infected Ugandan fishermen before treatment and 24 h...
Pierrot, Christine, Wilson, Shona, Lallet, Hélène, Lafitte, Sophia, Jones, Frances M., Daher, Wassim, ...
Plasmodium falciparum and Schistosoma mansoni are often found in human coinfections, and cross-reactive antibodies to different components of the two parasites have been detected. In this work, we...
Wilson, Shona, Booth, Mark, Jones, Frances M, Mwatha, Joseph K, Kimani, Gachuhi, Kariuki, H Curtis, ...
Wilson, Shona, Jones, Frances M., Mwatha, Joseph K., Kimani, Gachuhi, Booth, Mark, Kariuki, H. Curtis, ...
Hepatosplenomegaly among Kenyan schoolchildren has been shown to be exacerbated where there is transmission of both Schistosoma mansoni and Plasmodium falciparum. This highly prevalent and chronic...