A secretory phospholipase A2-mediated neuroprotection and anti-apoptosis (2009)
Armugam, Arunmozhiarasi, Cher, Charmian DN, Lim, KaiYing, Koh, Dawn CI, Howells, David W, Jeyaseelan, Kandiah
Abstract Background Phospholipase A 2 liberates free fatty acids and lysophospholipids upon hydrolysis of phospholipids and these products are often associated with detrimental effects such as...
Good laboratory practice: preventing introduction of bias at the bench (2009)
Macleod, Malcolm R., Fisher, Marc, O'Collins, Victoria, Sena, Emily S., Dirnagl, Ulrich, Bath, Philip M.W., ...
Background and Purpose—As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human...
Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis (2007)
Van Der Worp, H. Bart, Sena, Emily S., Donnan, Geoffrey A., Howells, David W., Macleod, Malcolm R.
Induced hypothermia is proposed as a treatment for acute ischaemic stroke, but there have been too few clinical trials involving too few patients to draw any conclusions about the therapeutic benefit...