A PROPOSAL FOR A USER-LEVEL, MESSAGE-PASSING INTERFACE IN A DISTRIBUTED MEMORY ENVIRONMENT (2009)
Rolf Hempel, Rolf Hempel, ...
Ireland, Zoe, Russell, Aaron P, Wallimann, Theo, Walker, David W, Snow, Rod
Abstract Background Creatine synthesis takes place predominately in the kidney and liver via a two-step process involving AGAT ( L -arginine:glycine amidinotransferase) and GAMT (guanidinoacetate...
Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz (2009)
Hull-Thompson, Julie, Muffat, Julien, Sanchez, Diego, Walker, David W., Benzer, Seymour, Ganfornina, Maria D., ...
Metabolic homeostasis in metazoans is regulated by endocrine control of insulin/IGF signaling (IIS) activity. Stress and inflammatory signaling pathways—such as Jun-N-terminal Kinase (JNK)...
Support for Provenance in a Service-based Computing Grid (2008)
There is underlying need to support data provenance in a service-based computing environment such as the Grid where web services may be automatically discovered, composed, and then consumed using...
A Mobile Agent-Based Architecture for On-Demand Processing of Remote-Sensing Archive (2008)
Yanyan Yang, Omer F. Rana, David W. Walker, Roy Williams
Abstract appears to be promising due to the following reasons: Remote-sensing data about the Earth 5 environment is being created at an ever- increasing rate and distributed among heterogeneous...
Muffat, Julien, Walker, David W., Benzer, Seymour
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing...
Agency under contract DAAL03-9 1-C-0047, administered by the
A Grid-based Problem Solving Environment for GECEM (2008)
Grid-enabled portals are becoming increasingly popular as a means to create Grid-based problem-solving environments (PSEs) that allow scientists to access distributed resources, and to monitor and...
Grid Enabled Remote Visualization of Medical Datasets (2008)
Nick J. Avis, Ian J. Grimstead, David W. Walker
We present an architecture for remote visualization of datasets over the Grid. This permits an implementation-agnostic approach, where different systems can be discovered, reserved and orchestrated...
David W Walker, Robert J. Allan, John Darlington
The Grid computing community is now converging on a service-oriented architecture in which applications are composed from geographically dispersed, interacting Web services, and expressed in a...
� Serviço de Leasing � Limitação de tempo (2008)
Ali Shaikhali, Omer F. Rana, Rashid Al-li, David W. Walker, Bruno Ramos Menegasso, Professora Ph, ...
� Localização e utilização de serviços � API’s especificadas em WSDL
Ireland, Zoe, Dickinson, Hayley, Snow, Rod, Walker, David W.
Objective We hypothesized that elevating creatine in the maternal diet would reach fetal and placental tissues and improve fetal survival after acute hypoxia at birth.Study DesignPregnant spiny mice...
Jack J. Dongarra, Roldan Pozo, David W. Walker
LAPACK++ is an object-oriented C++ extension of the LAPACK ( Linear Algebra PACKage) library for solving the common problems of numerical linear algebra: linear systems, linear least squares, and...
Bringing together Mobile Agents and Data Analysis in PSEs (2007)
Omer Rana And, Omer F. Rana, Omer F. Rana, David W. Walker, David W. Walker
We explore an approach based on remote evaluation, rather than the traditional TCP/IP based remote procedure calls for parallelism on a network of workstations. The remote evaluation approach is...
Engineering Physics And, Jack J. Dongarra, Rolf Hempel, David W. Walker
This paper describes Message Passing Interface 1 (MPI1), a proposed library interface standard for supporting point-to-point message passing. The intended standard will be provided with Fortran 77...
Constructing Numerical Software Libraries for High-Performance Computing Environments (2007)
Jaeyoung Choi, Jack J. Dongarra, Roldan Pozo, David W. Walker
In this paper we look at a number of approaches being investigated in the ScaLAPACK Project to develop linear algebra software for high-performance computers. The focus is on issues impacting the...
Paradigms And Strategies For Scientific Computing On Distributed Memory Concurrent Computers (2007)
Ian Foster, Ian T. Foster, David W. Walker, David W. Walker, David W. Walker
In this work we examine recent advances in parallel languages and abstractions that have the potential for improving the programmability and maintainability of largescale, parallel, scientific...
Engineering Physics, Jack J. Dongarra, Rolf Hempel, David W. Walker
This paper describes Message Passing Interface 1 (MPI1), a proposed library interface standard for supporting point-to-point message passing. The intended standard will be provided with Fortran 77...
G-QoSM: A Framework for Quality of Service Management (2007)
Some applications utilizing Grid computing infrastructure require the simultaneous allocation of resources, such as compute servers, networks, memory, disk storage and other specialized resources....
Architecture of an Intelligent Resource Management (2007)
Omer F. Rana, David W. Walker, Yan Huang
Implementing scientific or commercial applications on distributed heterogeneous computing systems, generally coiled 'Metacomputing', has recently become an active reseoxch oxea within the...
Matthew S. Shields, Omer F. Rana, David W. Walker, Maozhen Li, David Golby
A Problem Solving Environment (PSE) is a complete, integrated computing environment for composing, compiling and running applications in a specific problem area or domain. Parts of the PSE are domain...
Walker, David W., Hájek, Petr, Muffat, Julien, Knoepfle, Dan, Cornelison, Stephanie, Attardi, Giuseppe, ...
Oxidative stress is implicated as a major cause of aging and age-related diseases, such as Parkinson's and Alzheimer's, as well as ischemia-reperfusion injury in stroke. The mitochondrial electron...
Stress in pregnancy activates neurosteroid production in the fetal brain (2006)
Hirst, Jonathan J., Yawno, Tamara, Nguyen, Phuong, Walker, David W.
Neurosteroids such as allopregnanolone are potent agonists at the GABAA receptor and suppress the fetal CNS activity. These steroids are synthesized in the fetal brain either from cholesterol or from...
Stress in pregnancy activates neurosteroid production in the fetal brain (2006)
Hirst, Jonathan J., Yawno, Tamara, Nguyen, Phuong, Walker, David W.
Neurosteroids such as allopregnanolone are potent agonists at the GABAA receptor and suppress the fetal CNS activity. These steroids are synthesized in the fetal brain either from cholesterol or from...
Differential patterns of apoptosis in response to aging in Drosophila (2005)
Zheng, Jie, Edelman, Scott W., Tharmarajah, Grace, Walker, David W., Pletcher, Scott D., Seroude, Laurent
Several lines of evidence suggest that programmed cell death may play a role in the aging process and the age-related functional declines of multicellular organisms. To pave the way for the use of...
Grid enabled remote visualization of medical datasets (2005)
Avis, Nick J., Grimstead, Ian J., Walker, David W.
We present an architecture for remote visualization of datasets over the Grid. This permits an implementation-agnostic approach, where different systems can be discovered, reserved and orchestrated...
The spiny mouse (Acomys cahirinus) completes nephrogenesis before birth (2005)
Dickinson, Hayley, Walker, David W., Cullen-Walker, Luise, Wintour, Marelyn, Moritz, Karen
The spiny mouse is relatively mature at birth. We hypothesized that like other organs, the kidney may be more developed in the spiny mouse at birth, than in other rodents. If nephrogenesis is...
The spiny mouse (Acomys cahirinus) completes nephrogenesis before birth (2005)
Dickinson, Hayley, Walker, David W., Cullen-Walker, Luise, Wintour, Marelyn, Moritz, Karen
The spiny mouse is relatively mature at birth. We hypothesized that like other organs, the kidney may be more developed in the spiny mouse at birth, than in other rodents. If nephrogenesis is...
D.: Resource-aware visualization using web services (2005)
Ian J. Grimstead, Nick J. Avis, David W. Walker, Roger N. Philp
Abstract — We present a status report on RAVE, our distributed, collaborative grid enabled visualization environment. We briefly review our architecture and related work, examine our collaborative...
A Performance Evaluation of Using SOAP with Attachments for e-Science (2005)
Ying Ying, Yan Huang, David W. Walker
SOAP is now commonly used as the main transport protocol in Service-Oriented Architectures (SOA), but it is debatable whether SOAP can really meet the performance needs of e-Science. This paper...
Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl (2004)
Walker, David W., Benzer, Seymour
Mitochondrial dysfunction and reactive oxygen species have been implicated in the aging process as well as a wide range of hereditary and age-related diseases. Identifying primary events that result...
Automated composition of semantic grid services (2004)
Shalil Majithia, David W. Walker, W. A. Gray
We present an architecture to facilitate automated discovery, selection, and composition of Semantic Grid services. Our framework has two main features which distinguish it from other work in this...
Analysis and Provision of QoS for Distributed Grid Applications (2004)
Kaizar Amin, Gregor Von Laszewski, Omer F, David W. Walker, Mihael Hategan, ...
Grid computing provides the infrastructure necessary to access and use distributed resources as part of virtual organizations. When used in this way, Grid computing makes it possible for users to...
Automated Web service composition using semantic Web technologies (2004)
Shalil Majithia, David W. Walker, W. A. Gray
We present an architecture to facilitate automated discovery, selection, and composition of semanticallydescribed heterogeneous services using Semantic Web technologies. Our framework has three main...
Analysis and Provision of QoS for Distributed Grid Applications (2004)
Kaizar Amin, Gregor Von Laszewski, Omer F, David W. Walker, ...
Grid computing provides the infrastructure necessary to access and use distributed resources as part of virtual organizations. When used in this way, Grid computing makes it possible for users to...
A framework for automated service composition in service-oriented architecture (2004)
Shalil Majithia, David W. Walker, W. A. Gray
Abstract. Automated service composition refers to automating the entire process of composing a workflow. This involves automating the discovery and selection of the service, ensuring semantic and...
Qos adaptation in service-oriented grids (2003)
Rashid Al-ali, Abdelhakim Hafid, Omer F. Rana, David W. Walker
Some applications utilizing Grid computing infrastructure require the simultaneous allocation of resources, such as compute servers, networks, memory, disk storage and other specialized resources....
Wrapping Legacy Codes for Grid-Based Applications (2003)
Yan Huang, Ian Taylor, David W. Walker
This paper describes a process for the semi-automatic conversion of numerical and scientific routines written in the C programming language into Triana-based computational services that can be used...
GECEM: Grid-Enabled Computational Electromagnetics (2003)
David W. Walker, Jonathan P. Giddy, Alan Gould, David Rowse, Michael Turner, Nigel P. Weatherill, ...
The GECEM project aims to use and develop Grid technology to enable large-scale and globallydistributed scientific and engineering research. The focus of the project is collaborative numerical...
G-QoSM: Grid service discovery using QoS properties (2002)
Omer F. Rana, David W. Walker, Sanjay Jha, Shaleeza Sohail
We extend the service abstraction in the Open Grid Services Architecture[12] for Quality of Service (QoS) properties. The realization of QoS often requires mechanisms such as advance or on-demand...
GuhaThakurta, Debraj, Palomar, Lisanne, Stormo, Gary D., Tedesco, Pat, Johnson, Thomas E., Walker, David W., ...
Resource Discovery for Dynamic Clusters in Computational Grids (2001)
Rana, Omer F., Bunford-Jones, Daniel, Hawick, K. A., Walker, David W., Addis, Matthew, Surridge, M
Resource Discovery for Dynamic Clusters in Computational Grids (2001)
Rana, Omer F., Bunford-Jones, Daniel, Hawick, K. A., Walker, David W., Addis, Matthew, Surridge, M
Resource Discovery for Dynamic Clusters in Computational Grids (2001)
Rana, Omer F., Bunford-Jones, Daniel, Hawick, K. A., Walker, David W., Addis, Matthew, Surridge, M
Mobile Agent on the SARA Digital Library (2000)
Yang, Yanyan, Rana, Omer F., Walker, David W., Georgousopoulos, Christ, Williams, Roy
Remote-sensing data about the Earth's environment is being created at an ever-increasing rate and distributed among heterogeneous remote sites. Traditional models of distributed computing are...
Mobile agents and the sara digital library (2000)
Christ Georgousopoulos, Yanyan Yang, Yanyan Yang, Omer F. Rana, Omer F. Rana, David W. Walker, ...
Remote-sensing data about the Earth’s environment is being created at an ever-increasing rate and distributed among heterogeneous remote sites. Traditional models of distributed computing are...
Chapter in Wiley Encyclopedia of Electrical and Electronics Engineering (1999)
Jack J. Dongarra, Graham E. Fagg, Rolf Hempel, David W. Walker
messages
Chapter in Wiley Encyclopedia of Electrical and Electronics Engineering (1999)
Jack J. Dongarra, Graham E. Fagg, Rolf Hempel, David W. Walker
ions, such as procedures, make the exploitation of modularity easier by allowing objects to be manipulated without concern for their internal structure. High-level languages, such as Fortran, Pascal,...
Bringing together Mobile Agents and Numerical Analysis in PSEs (1999)
Omer Rana And, Omer F. Rana, David W. Walker
We explore an approach based on remote evaluation, rather than the traditional TCP/IP based remote procedure calls for parallelism on a network of workstations. The remote evaluation approach is...
Walker, David W., Stout, Quentin F.
Contents; Expert systems; Alternate applications; Multi target tracking; Simulation of systems and discrete events; Path planning and navigation; Data and image processing; Computer vision; Ray...
Walker, David W., Stout, Quentin F.
Contents: Overviews; Dual ported memory computers; Shared memory; Other hardware and architectures; Distributed computing; Communication systems; Routing; Fault tolerance; Matrix decomposition and...
Mpi: A Standard Message Passing Interface (1996)
David Walker Mathematical, David W. Walker, David W. Walker, Jack J. Dongarra, Jack J. Dongarra
ion Communicators provide support for the design of safe, modular software libraries. Here "safe" means that messages intended for receipt by a particular receive call in an application...
The Design and Implementation of the ScaLAPACK LU, QR and Cholesky Factorization Routines (1996)
Scalapack Lu, Jack J. Dongarra, Factorization Routines, Jaeyoung Choi, ...
This paper discusses the core factorization routines included in the ScaLAPACK library. These routines allow the factorization and solution of a dense system of linear equations via LU, QR, and...
Key Concepts For Parallel Out-Of-Core LU Factorization (1996)
Jack Dongarra Sven, Sven Hammarling, David W. Walker
This paper considers key ideas in the design of out-of-core dense LU factorization routines. A left-looking variant of the LU factorization algorithm is shown to require less I/O to disk than the...
Key Concepts For Parallel Out-Of-Core LU Factorization (1996)
Jack J. Dongarra, Sven Hammarling, David W. Walker
This paper considers key ideas in the design of out-of-core dense LU factorization routines. A left-looking variant of the LU factorization algorithm is shown to require less I/O to disk than the...
An MPI Implementation of the BLACS (1996)
Vaibhav Deshpande, William Sawyer, David W. Walker
An MPI implementation of the Basic Linear Communication Subprograms (BLACS) is presented. A wide spectrum of MPI functionality has been used to implement BLACS as succinctly as possible, thus making...
Key Concepts for Parallel Out-of-Core LU Factorization (1996)
Jack J. Dongarra, Sven Hammarling, David W. Walker
This paper considers key ideas in the design of out-of-core dense LU factorization routines. A left-looking variant of the LU factorization algorithm is shown to require less I/O to disk than the...
Key Concepts For Parallel Out-Of-Core LU Factorization (1996)
Jack Dongarra, Jack J. Dongarra, Sven Hammarling, Sven Hammarling, David W. Walker, David W. Walker
This paper considers key ideas in the design of out-of-core dense LU factorization routines. A left-looking variant of the LU factorization algorithm is shown to require less I/O to disk than the...
Key Concepts For Parallel Out-Of-Core LU Factorization (1996)
Jack Dongarra, Sven Hammarling, David W. Walker
This paper considers key ideas in the design of out-of-core dense LU factorization routines. A left-looking variant of the LU factorization algorithm is shown to require less I/O to disk than the...
MPI: A Standard Message Passing Interface (1996)
David W. Walker, David W. Walker, Jack J. Dongarra, Jack J. Dongarra
ion Communicators provide support for the design of safe, modular software libraries. Here "safe" means that messages intended for receipt by a particular receive call in an application...
Key Concepts for Parallel Out-Of-Core LU Factorization (1996)
Jack J. Dongarra, Sven Hammarling, David W. Walker
This paper considers key ideas in the design of out-of-core dense LU factorization routines. A left-looking variant of the LU factor-ization algorithm is shown to require less I/O to disk than the...
Software libraries for linear algebra computations on high performance computers (1995)
Jack J. Dongarra, David W. Walker
This paper discusses the design of linear algebra libraries for high performance computers. Particular emphasis is placed on the development of scalable algorithms for MIMD distributed memory...
Software libraries for linear algebra computations on high performance computers (1995)
Jack J. Dongarra, David W. Walker
This paper discusses the design of linear algebra libraries for high performance computers. Particular emphasis is placed on the development of scalable algorithms for MIMD distributed memory...
J. Choi, Bidiagonal Form, Jaeyoung Choi, Jack J. Dongarra, David W. Walker
This paper discusses issues in the design of ScaLAPACK, a software library for performing dense linear algebra computations on distributed memory concurrent computers. These issues are illustrated...
Software Libraries For Linear Algebra Computations On High Performance Computers (1995)
Jack J. Dongarra, David W. Walker
This paper discusses the design of linear algebra libraries for high performance computers. Particular emphasis is placed on the development of scalable algorithms for MIMD distributed memory...
Software Libraries For Linear Algebra Computations On High Performance Computers (1995)
Jack J. Dongarra, Jack J. Dongarra, David W. Walker, David W. Walker, David W. Walker
This paper discusses the design of linear algebra libraries for high performance computers. Particular emphasis is placed on the development of scalable algorithms for MIMD distributed memory...
Software libraries for linear algebra computations on high performance computers (1995)
Jack J. Dongarra, David W. Walker
This paper discusses the design of linear algebra libraries for high performance computers. Particular emphasis is placed on the development of scalable algorithms for MIMD distributed memory...
Software libraries for linear algebra computations on high performance computers (1995)
Jack J. Dongarra, David W. Walker
This paper discusses the design of linear algebra libraries for high performance computers. Particular emphasis is placed on the development of scalable algorithms for MIMD distributed memory...
This paper presents an overview of mpi, a proposed standard message passing interface for MIMD distributed memory concurrent computers. The design of mpi has been a collective effort involving...
An MPI Version of the BLACS (1994)
In this paper, issues related to implementing an MPI version of the Basic Linear Communication Subprograms (BLACS) are investigated. A set of routines, the MPI Linear Algebra Communication...
CRPC Research into Linear Algebra Software for High Performance Computers (1994)
Jaeyoung Choi, Jack J. Dongarra, Roldan Pozo, Danny C. Sorensen, David W. Walker, David W. Walker
In this paper we look at a number of approaches being investigated in the Center for Research on Parallel Computation (CRPC) to develop linear algebra software for high-performance computers. These...
The Design and Implementation of the ScaLAPACK LU, QR and Cholesky Factorization Routines (1994)
Scalapack Lu, Factorization Routines, Jaeyoung Choi, David W. Walker, R. Clint Whaley, ...
This paper discusses the core factorization routines included in the ScaLAPACK library. These routines allow the factorization and solution of a dense system of linear equations via LU, QR, and...
Scalability Issues Affecting the Design of a Dense Linear Algebra Library (1994)
Jack J. Dongarra, David W. Walker
This paper discusses the scalability of Cholesky, LU, and QR factorization routines on MIMD distributed memory concurrent computers. These routines form part of the ScaLAPACK mathematical software...
Scalability Issues Affecting The Design Of A Dense Linear Algebra Library (1994)
Jack J. Dongarra, Jack J. Dongarra, David W. Walker, David W. Walker, ...
This paper discusses the scalability of Cholesky, LU, and QR factorization routines on MIMD distributed memory concurrent computers. These routines form part of the ScaLAPACK mathematical software...
Paradigms And Strategies For Scientific Computing On Distributed Memory Concurrent Computers (1994)
Ian T. Foster, Ian T. Foster, David W. Walker
In this work we examine recent advances in parallel languages and abstractions that have the potential for improving the programmability and maintainability of largescale, parallel, scientific...
Jaeyoung Choi, Jaeyoung Choi, Jaeyoung Choi, Jack J. Dongarra, Jack J. Dongarra, David W. Walker, ...
This paper describes the Parallel Universal Matrix Multiplication Algorithms (PUMMA) on distributed memory concurrent computers. The PUMMA package includes not only the nontransposed matrix...
Jack J. Dongarra, David W. Walker, Jaeyoung Choi
der contract DAAL03-91-G0047, administered by the Army Re-
Jaeyoung Chai, Jack J. Ngasra, David W. Walker, Jaeyoung Choi, Jack J. Dongarra, David W. Walker
der contract DAAL03-91-C-0047, administered by the Army Re-
Jack Dongarra Roldan, Jack J. Dongarra, Roldan Pozo, David W. Walker
We describe the design of ScaLAPACK++, an object oriented C++ library for implementing linear algebra computations on distributed memory multicomputers. This package, when complete, will support...
LAPACK++: A Design Overview of Object-Oriented Extensions for High Performance Linear Algebra (1993)
Jack J. Dongarra, Roldan Pozo, David W. Walker
LAPACK++ is an object-oriented C++ extension of the LAPACK ( Linear Algebra PACKage) library for solving the common problems of numerical linear algebra: linear systems, linear least squares, and...
Jack J. Dongarra, Roldan Pozo, David W. Walker
We describe the design of ScaLAPACK++, an object oriented C++ library for implementing linear algebra computations on distributed memory multicomputers. This package, when complete, will support...
Parallel Matrix Transpose Algorithms On Distributed Memory Concurrent Computers (1993)
Jaeyoung Choi, Jack J. Dongarra, David W. Walker, David W
This paper describes parallel matrix transpose algorithms on distributed memory concurrent processors. We assume that the matrix is distributed over a P \Theta Q processor template with a block...
A Proposal for a User-Level, Message-Passing Interface in a Distributed Memory Environment (1993)
Jack Dongarra, Rolf Hempel, David W. Walker
TPUT ARGUMENTS ilist an integer array DESCRIPTION MPI INFOMN returns in the array ilist a list of integers that characterize the machine that the calling process is running on. The first integer in...
Parallel Matrix Transpose Algorithms on Distributed Memory Concurrent Computers (1993)
Jack J. Dongarra, David W. Walker, Jaeyoung Choi, Jaeyoung Choi
This paper describes parallel matrix transpose algorithms on distributed memory concurrent processors. We assume that the matrix is distributed over a P \Theta Q processor template with a block...
Jaeyong Choi, Jack J. Dongarra, David W. Walker
0-5, NASA Ames Research Center, Moffet Field, CA 94035 134. William C. Skamarock, 3973 Escuela Court, Boulder, CO 80301 135. Richard Smith, Los Alamos National Laboratory, Group T-3, Mail Stop B2316,...
A Scalable Linear Algebra Library for Distributed Memory Concurrent Computers (1992)
Jaeyoung Choi, Jack J. Dongarra, Roldan Pozo, David W. Walker
This paper describes ScaLAPACK, a distributed memory version of the LAPACK software package for dense and banded matrix computations. Key design features are the use of distributed versions of the...
Concurrency:practice Experience, (1992)
Oct Parallelizing, David W. Walker, Patrick H. Worley, B. Drake
. The spectral transform method is a widely-used numerical technique for solving partial differential equations on the sphere in global climate modeling. This paper describes the parallelization and...
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Parentesco, Negocios y Política. La Familia Martínez del Río en México, 1823-1 (1991)
En esta obra, el autor elige a la familia Martínez del Rio, importantes comerciantes panameños emigrados a México, como instrumento conceptual que sirve para explorar las repercusiones de los...
Parentesco, Negocios y Política. La Familia Martínez del Río en México, 1823-1 (1991)
En esta obra, el autor elige a la familia Martínez del Rio, importantes comerciantes panameños emigrados a México, como instrumento conceptual que sirve para explorar las repercusiones de los...
Maternal pinealectomy alters the daily pattern of fetal breathing in sheep (1990)
McMillen, Isabella Caroline, Nowak, Rachel, Walker, David W, Young, I R
Maternal pinealectomy alters the daily pattern of fetal breathing in sheep (1990)
McMillen, Isabella Caroline, Nowak, Rachel, Walker, David W, Young, I R
Maternal pinealectomy alters the daily pattern of fetal breathing in sheep (1990)
McMillen, Isabella Caroline, Nowak, Rachel, Walker, David W, Young, I R
Thesis (Ph. D.)--University of Reading, 1981.
Summary: p. v-vi. Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy.
Lessons Learned from the GECEM Project (1970)
The Grid-Enabled Computational Electromagnetics project (GECEM) has developed a portal for performing electromagnetics simulations. The portal is based on the GridSphere portal framework and uses...
GuhaThakurta, Debraj, Palomar, Lisanne, Stormo, Gary D., Tedesco, Pat, Johnson, Thomas E., Walker, David W., ...
We report here the identification of a previously unknown transcription regulatory element for heat shock (HS) genes in Caenorhabditis elegans. We monitored the expression pattern of 11,917 genes...
Mitochondrial “swirls” induced by oxygen stress and in the Drosophila mutant hyperswirl
Walker, David W., Benzer, Seymour
Mitochondrial dysfunction and reactive oxygen species have been implicated in the aging process as well as a wide range of hereditary and age-related diseases. Identifying primary events that result...
Differential patterns of apoptosis in response to aging in Drosophila
Zheng, Jie, Edelman, Scott W., Tharmarajah, Grace, Walker, David W., Pletcher, Scott D., Seroude, Laurent
Several lines of evidence suggest that programmed cell death may play a role in the aging process and the age-related functional declines of multicellular organisms. To pave the way for the use of...
Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion
Nguyen, Phuong N, Yan, Edwin B, Castillo-Melendez, Margie, Walker, David W, Hirst, Jonathan J
Allopregnanolone (AP) is a potent modulator of the GABAA receptor. Brain AP concentrations increase in response to stress, which is thought to provide neuroprotection by reducing excitation in the...
GuhaThakurta, Debraj, Palomar, Lisanne, Stormo, Gary D., Tedesco, Pat, Johnson, Thomas E., Walker, David W., ...
We report here the identification of a previously unknown transcription regulatory element for heat shock (HS) genes in Caenorhabditis elegans. We monitored the expression pattern of 11,917 genes...
Mitochondrial “swirls” induced by oxygen stress and in the Drosophila mutant hyperswirl
Walker, David W., Benzer, Seymour
Mitochondrial dysfunction and reactive oxygen species have been implicated in the aging process as well as a wide range of hereditary and age-related diseases. Identifying primary events that result...
Differential patterns of apoptosis in response to aging in Drosophila
Zheng, Jie, Edelman, Scott W., Tharmarajah, Grace, Walker, David W., Pletcher, Scott D., Seroude, Laurent
Several lines of evidence suggest that programmed cell death may play a role in the aging process and the age-related functional declines of multicellular organisms. To pave the way for the use of...
Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion
Nguyen, Phuong N, Yan, Edwin B, Castillo-Melendez, Margie, Walker, David W, Hirst, Jonathan J
Allopregnanolone (AP) is a potent modulator of the GABAA receptor. Brain AP concentrations increase in response to stress, which is thought to provide neuroprotection by reducing excitation in the...
Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant
Walker, David W., Hájek, Petr, Muffat, Julien, Knoepfle, Dan, Cornelison, Stephanie, Attardi, Giuseppe, ...
Oxidative stress is implicated as a major cause of aging and age-related diseases, such as Parkinson's and Alzheimer's, as well as ischemia-reperfusion injury in stroke. The mitochondrial electron...
Intravenous infusion of probencid (79-160 mg kg−1) into unanaesthetized fetal sheep (127-143 days gestation) in utero significantly decreased the incidence and amplitude of spontaneous breathing...
Typescript.
Muffat, Julien, Walker, David W., Benzer, Seymour
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing...
General Bibliography and Further Readings for CSI
J. E. Gentle, Ian G, Geoffrey C. Fox, Jai Sam Kim, David W. Walker, Y. Dodge, ...
Barrodale, I., and F. D. K. Roberts (1974), Algorithm 478: Solution of an overdetermined system of Equations in the l 1 norm, Communications of the ACM 17, 319--320. Bates, D. M., and D. G. Watts...
Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz
Hull-Thompson, Julie, Muffat, Julien, Sanchez, Diego, Walker, David W., Benzer, Seymour, Ganfornina, Maria D., ...
Metabolic homeostasis in metazoans is regulated by endocrine control of insulin/IGF signaling (IIS) activity. Stress and inflammatory signaling pathways—such as Jun-N-terminal Kinase (JNK)...