Deborah Ashby

Financial incentives to improve adherence to anti-psychotic maintenance medication in non-adherent patients: a cluster randomised controlled trial (FIAT) (2009)

Priebe, Stefan, Burton, Alexandra, Ashby, Deborah, Ashcroft, Richard, Burns, Tom, David, Anthony, ...

Background: Various interventions have been tested to achieve adherence to anti-psychotic maintenance medication in non-adherent patients with psychotic disorders, and there is no consistent evidence...

Financial incentives to improve adherence to anti-psychotic maintenance medication in non-adherent patients - a cluster randomised controlled trial (FIAT) (2009)

Priebe, Stefan, Burton, Alexandra, Ashby, Deborah, Ashcroft, Richard, Burns, Tom, David, Anthony, ...

Abstract Background Various interventions have been tested to achieve adherence to anti-psychotic maintenance medication in non-adherent patients with psychotic disorders, and there is no consistent...

(www.interscience.wiley.com) DOI: 10.1002/sim.2672 Paper Celebrating the 25th Anniversary of Statistics in Medicine Bayesian statistics in medicine: A 25 year review ‡ (2008)

Statist Med, Deborah Ashby, John Wiley

This review examines the state of Bayesian thinking as Statistics in Medicine was launched in 1982, reflecting particularly on its applicability and uses in medical research. It then looks at each...

European regulatory agencies should employ full time statisticians (2008)

Hughes, Sara, Keene, Oliver, Howitt, Nigel, Roes, Kit, Ashby, Deborah, Beltangady, Mohan, ...

Univ London, Queen Mary, London WC1E 7HU, England. Royal Stat Soc, Cambridge, England. MRC, Biostat Unit, Cambridge CB2 2BW, England. Hasselt Univ, Int Inst Drug Dev, Hasselt, Belgium. Roche Prod...

Managing Injuries of the Neck Trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders (2007)

Lamb, Sarah E, Gates, Simon, Underwood, Martin R, Cooke, Matthew W, Ashby, Deborah, Szczepura, Ala, ...

Abstract Background A substantial proportion of patients with whiplash injuries develop chronic symptoms. However, the best treatment of acute injuries to prevent long-term problems is uncertain. A...

Managing Injuries of the Neck Trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders (2007)

Lamb, Sarah E., Gates , Simon, Underwood, Martin R., Cooke, Matthew W., Ashby, Deborah, Szczepura, Ala, ...

Background: A substantial proportion of patients with whiplash injuries develop chronic symptoms. However, the best treatment of acute injuries to prevent long-term problems is uncertain. A stepped...

Is it exposure to cigarette smoke or to smokers which increases the risk of meningococcal disease in teenagers? (2006)

Coen, Pietro G, Tully, Joanna, Stuart, James M, Ashby, Deborah, Viner, Russell M, Booy, Robert

Background Passive smoking appears to increase the risk of meningococcal disease (MD) in adolescents. Whether this effect is attributable to exposure to cigarette smoke or contact with smokers is...

Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method (2006)

Eldridge, Sandra M, Ashby, Deborah, Kerry, Sally

Background Cluster randomized trials are increasingly popular. In many of these trials, cluster sizes are unequal. This can affect trial power, but standard sample size formulae for these trials...

Is it exposure to cigarette smoke or to smokers which increases the risk of meningococcal disease in teenagers? (2006)

Coen, Pietro G., Tully, Joanna, Stuart, James M., Ashby, Deborah, Viner, Russell M., Booy, Robert

Background Passive smoking appears to increase the risk of meningococcal disease (MD) in adolescents. Whether this effect is attributable to exposure to cigarette smoke or contact with smokers is...

Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method (2006)

Eldridge, Sandra M., Ashby, Deborah, Kerry, Sally

Background Cluster randomized trials are increasingly popular. In many of these trials, cluster sizes are unequal. This can affect trial power, but standard sample size formulae for these trials...

TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052] (2005)

Cross, Pamela L, Ashby, Deborah, Harding, Geoff, Hennessy, Enid M, Letley, Louise, Parsons, Suzanne, ...

Abstract Background Many older people have chronic knee pain. Both topical and oral non- steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat this. Oral NSAIDS are effective, at...

BMJ statistical errors (2004)

Cole, Tim J, Altman, Douglas, Ashby, Deborah, Campbell, Mike, Deeks, Johnathan, Evans, Stephen, ...

EDITOR—Abbasi in his Editor's choice discusses a study that found statistical errors in 25% of papers published by the BMJ in 2001.1 As statistical advisers to the BMJ we aim to improve the quality...

A Brief Sensitive Screening Instrument for Depression in Late Life (1994)

ALLEN, NICHOLAS, AMES, DAVID, ASHBY, DEBORAH, BENNETTS, KERRYN, TUCKWELL, VIRGINIA, WEST, CHRISTOPHER

Data collected with the depression scale (DEP) of the Brief Assessment Scale (BAS) at interviews with 811 elderly subjects were analysed to determine which of its 21 individual items could be...

Lead Exposure and Children's Intellectual Performance (1987)

POCOCK, STUART J, ASHBY, DEBORAH, SMITH, MARJORIE A

The Institute of Child Health/Southampton study is the largest cross-sectional survey of lead exposure and children's intelligence. 402 six year olds in London with tooth lead concentration in...

PSYCHIATRIC ILLNESS IN RESIDENTIAL HOMES FOR THE ELDERLY: A SURVEY IN ONE LONDON BOROUGH (1984)

MANN, ANTHONY H., GRAHAM, NORI, ASHBY, DEBORAH

The mental state, demographic details, dependency level and presence of problem behaviours have been recorded for 438 (82%) of the residents of the 12 Part III homes, managed by the London...

Selective serotonin reuptake inhibitors (SSRIs) and suicide in adults: meta-analysis of drug company data from placebo controlled, randomised controlled trials submitted to the MHRA's safety review

Gunnell, David, Saperia, Julia, Ashby, Deborah

Objective To investigate whether selective serotonin reuptake inhibitor (SSRI) antidepressants are associated with an increased risk of suicide related outcomes in adults.

Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study

Martinez, Carlos, Rietbrock, Stephan, Wise, Lesley, Ashby, Deborah, Chick, Jonathan, Moseley, Jane, ...

Objective To compare the risk of non-fatal self harm and suicide in patients taking selective serotonin reuptake inhibitors (SSRIs) with that of patients taking tricyclic antidepressants, as well as...

Oral protein energy supplements for children with cystic fibrosis: CALICO multicentre randomised controlled trial

Poustie, Vanessa J, Russell, Jayne E, Watling, Ruth M, Ashby, Deborah, Smyth, Rosalind L

Objective To determine whether oral protein energy supplements, used long term in children with cystic fibrosis who are moderately malnourished, improve nutritional and other outcomes.

Selective serotonin reuptake inhibitors (SSRIs) and suicide in adults: meta-analysis of drug company data from placebo controlled, randomised controlled trials submitted to the MHRA's safety review

Gunnell, David, Saperia, Julia, Ashby, Deborah

Objective To investigate whether selective serotonin reuptake inhibitor (SSRI) antidepressants are associated with an increased risk of suicide related outcomes in adults.

Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study

Martinez, Carlos, Rietbrock, Stephan, Wise, Lesley, Ashby, Deborah, Chick, Jonathan, Moseley, Jane, ...

Objective To compare the risk of non-fatal self harm and suicide in patients taking selective serotonin reuptake inhibitors (SSRIs) with that of patients taking tricyclic antidepressants, as well as...

Oral protein energy supplements for children with cystic fibrosis: CALICO multicentre randomised controlled trial

Poustie, Vanessa J, Russell, Jayne E, Watling, Ruth M, Ashby, Deborah, Smyth, Rosalind L

Objective To determine whether oral protein energy supplements, used long term in children with cystic fibrosis who are moderately malnourished, improve nutritional and other outcomes.

Advice to use topical or oral ibuprofen for chronic knee pain in older people: randomised controlled trial and patient preference study

Underwood, Martin, Ashby, Deborah, Cross, Pamela, Hennessy, Enid, Letley, Louise, Martin, Jeannett, ...

Objective To determine whether older patients with chronic knee pain should be advised to use topical or oral non-steroidal anti-inflammatory drugs (NSAIDs).

Internal and external validity of cluster randomised trials: systematic review of recent trials

Eldridge, Sandra, Ashby, Deborah, Bennett, Catherine, Wakelin, Melanie, Feder, Gene

Objectives To assess aspects of the internal validity of recently published cluster randomised trials and explore the reporting of information useful in assessing the external validity of these...