Deenadayalan Bakthavatsalam

A Dictyosteliumchalone uses G proteins to regulate proliferation (2009)

Bakthavatsalam, Deenadayalan, Choe, Jonathan M, Hanson, Nana E, Gomer, Richard H

Abstract Background Several studies have shown that organ size, and the proliferation of tumor metastases, may be regulated by negative feedback loops in which autocrine secreted factors called...

Dictyosteliumcells bind a secreted autocrine factor that represses cell proliferation (2009)

Choe, Jonathan M, Bakthavatsalam, Deenadayalan, Phillips, Jonathan E, Gomer, Richard H

Abstract Background Dictyostelium cells secrete the proteins AprA and CfaD. Cells lacking either AprA or CfaD proliferate faster than wild type, while AprA or CfaD overexpressor cells proliferate...

BMC Biochemistry BioMed Central (2009)

Jonathan M Choe, Deenadayalan Bakthavatsalam, Jonathan E Phillips, Richard H Gomer

Research article Dictyostelium cells bind a secreted autocrine factor that represses cell proliferation

The Dictyosteliumgenome encodes numerous RasGEFs with multiple biological roles (2005)

Wilkins, Andrew, Szafranski, Karol, Fraser, Derek J, Bakthavatsalam, Deenadayalan, Müller, Rolf, Fisher, Paul R, ...

Abstract Background Dictyostelium discoideum is a eukaryote with a simple lifestyle and a relatively small genome whose sequence has been fully determined. It is widely used for studies on cell...

A frizzled like protein in dictyostelium discoideum / (2004)

Bakthavatsalam, Deenadayalan.

Köln, University, Diss., 2005 (Nicht für den Austausch).

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles

Wilkins, Andrew, Szafranski, Karol, Fraser, Derek J, Bakthavatsalam, Deenadayalan, Müller, Rolf, Fisher, Paul R, ...

A survey of the Dictyostelium genome reveals at least 25 RasGEFs, all of which appear to be expressed at some point in development. Disruption of several of these novel RasGEFs reveals that many have...

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles

Wilkins, Andrew, Szafranski, Karol, Fraser, Derek J, Bakthavatsalam, Deenadayalan, Müller, Rolf, Fisher, Paul R, ...

A survey of the Dictyostelium genome reveals at least 25 RasGEFs, all of which appear to be expressed at some point in development. Disruption of several of these novel RasGEFs reveals that many have...

A Cell Number-Counting Factor Regulates Levels of a Novel Protein, SslA, as Part of a Group Size Regulation Mechanism in Dictyostelium▿

Gao, Tong, Roisin-Bouffay, Celine, Hatton, R. Diane, Tang, Lei, Brock, Debra A., DeShazo, Tiffany, ...

Developing Dictyostelium cells form aggregation streams that break into groups of ∼2 × 104 cells. The breakup and subsequent group size are regulated by a secreted multisubunit counting factor...

Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions

Mondal, Subhanjan, Bakthavatsalam, Deenadayalan, Steimle, Paul, Gassen, Berthold, Rivero, Francisco, Noegel, Angelika A.

Ras guanine nucleotide exchange factor (GEF) Q, a nucleotide exchange factor from Dictyostelium discoideum, is a 143-kD protein containing RasGEF domains and a DEP domain. We show that RasGEF Q can...