Cargo and Dynamin Regulate Clathrin-Coated Pit Maturation (2009)
Dinah Loerke, Marcel Mettlen, Defne Yarar, Khuloud Jaqaman, Henry Jaqaman, Gaudenz Danuser, ...
Total internal reflection fluorescence microscopy (TIR-FM) has become a powerful tool for studying clathrin-mediated endocytosis. However, due to difficulties in tracking and quantifying their...
A Dynamic Actin Cytoskeleton Functions at Multiple Stages of Clathrin-mediated Endocytosis □V (2004)
Clathrin-mediated endocytosis in mammalian cells is critical for a variety of cellular processes including nutrient uptake and cell surface receptor down-regulation. Despite the findings that...
Dissecting the mechanism of actin-based Motility mediated by WASP-family proteins / (2002)
Thesis (Ph.D. in Molecular and Cell Biology)--University of California, Berkeley, Fall 2002.
Mark Winey, Defne Yarar, Thomas H. Giddings, David N. Mastronarde
number of nuclear pore complexes (NPCs) in individual nuclei of the yeast Saccharomyces cerevisiae was determined by computer-aided reconstruction of entire nuclei from electron micrographs of...
Winey, Mark, Yarar, Defne, Giddings, Thomas H., Mastronarde, David N.
The number of nuclear pore complexes (NPCs) in individual nuclei of the yeast Saccharomyces cerevisiae was determined by computer-aided reconstruction of entire nuclei from electron micrographs of...
Motility Determinants in WASP Family ProteinsD⃞
Yarar, Defne, D'Alessio, Joseph A., Jeng, Robert L., Welch, Matthew D.
In response to upstream signals, proteins in the Wiskott-Aldrich Syndrome protein (WASP) family regulate actin nucleation via the Arp2/3 complex. Despite intensive study of the function of WASP...
Song, Byeong Doo, Yarar, Defne, Schmid, Sandra L.
Dynamin GTPase activity is required for its biological function in clathrin-mediated endocytosis; however, the role of self-assembly has not been unambiguously established. Indeed, overexpression of...
A Dynamic Actin Cytoskeleton Functions at Multiple Stages of Clathrin-mediated EndocytosisV⃞
Yarar, Defne, Waterman-Storer, Clare M., Schmid, Sandra L.
Clathrin-mediated endocytosis in mammalian cells is critical for a variety of cellular processes including nutrient uptake and cell surface receptor down-regulation. Despite the findings that...
SNX9 Regulates Dynamin Assembly and Is Required for Efficient Clathrin-mediated EndocytosisV⃞
Soulet, Fabienne, Yarar, Defne, Leonard, Marilyn, Schmid, Sandra L.
Dynamin, a central player in clathrin-mediated endocytosis, interacts with several functionally diverse SH3 domain-containing proteins. However, the role of these interactions with regard to dynamin...
Winey, Mark, Yarar, Defne, Giddings, Thomas H., Mastronarde, David N.
The number of nuclear pore complexes (NPCs) in individual nuclei of the yeast Saccharomyces cerevisiae was determined by computer-aided reconstruction of entire nuclei from electron micrographs of...
Motility Determinants in WASP Family ProteinsD⃞
Yarar, Defne, D'Alessio, Joseph A., Jeng, Robert L., Welch, Matthew D.
In response to upstream signals, proteins in the Wiskott-Aldrich Syndrome protein (WASP) family regulate actin nucleation via the Arp2/3 complex. Despite intensive study of the function of WASP...
Song, Byeong Doo, Yarar, Defne, Schmid, Sandra L.
Dynamin GTPase activity is required for its biological function in clathrin-mediated endocytosis; however, the role of self-assembly has not been unambiguously established. Indeed, overexpression of...
A Dynamic Actin Cytoskeleton Functions at Multiple Stages of Clathrin-mediated EndocytosisV⃞
Yarar, Defne, Waterman-Storer, Clare M., Schmid, Sandra L.
Clathrin-mediated endocytosis in mammalian cells is critical for a variety of cellular processes including nutrient uptake and cell surface receptor down-regulation. Despite the findings that...
SNX9 Regulates Dynamin Assembly and Is Required for Efficient Clathrin-mediated EndocytosisV⃞
Soulet, Fabienne, Yarar, Defne, Leonard, Marilyn, Schmid, Sandra L.
Dynamin, a central player in clathrin-mediated endocytosis, interacts with several functionally diverse SH3 domain-containing proteins. However, the role of these interactions with regard to dynamin...
Alto, Neal M., Weflen, Andrew W., Rardin, Matthew J., Yarar, Defne, Lazar, Cheri S., Tonikian, Raffi, ...
Bacterial toxins and effector proteins hijack eukaryotic enzymes that are spatially localized and display rapid signaling kinetics. However, the molecular mechanisms by which virulence factors engage...
Formation of filopodia-like bundles in vitro from a dendritic network
Vignjevic, Danijela, Yarar, Defne, Welch, Matthew D., Peloquin, John, Svitkina, Tatyana, Borisy, Gary G.
We report the development and characterization of an in vitro system for the formation of filopodia-like bundles. Beads coated with actin-related protein 2/3 (Arp2/3)–activating proteins can induce...
Cargo and Dynamin Regulate Clathrin-Coated Pit Maturation
Loerke, Dinah, Mettlen, Marcel, Yarar, Defne, Jaqaman, Khuloud, Jaqaman, Henry, Danuser, Gaudenz, ...
Total internal reflection fluorescence microscopy (TIR-FM) has become a powerful tool for studying clathrin-mediated endocytosis. However, due to difficulties in tracking and quantifying their...