Delphine Lavens

MAPPIT (Mammalian Protein-Protein Interaction Trap) analysis of early steps in Toll-Like receptor signalling (2009)

Ulrichts, Peter, Lemmens, Irma, Lavens, Delphine, Beyaert, Rudi, Tavernier, Jan

The mammalian protein-protein interaction trap (MAPPIT) is a two-hybrid technique founded on type I cytokine signal transduction. Thereby, bait and prey proteins are linked to signalling deficient...

The many faces of the SOCS box (2008)

Piessevaux, Julie, Lavens, Delphine, Peelman, Frank, Tavernier, Jan

The suppressors of cytokine signalling (SOCS) box is a structural domain found at the C-terminus of over 70 human proteins. It is usually coupled to a protein interaction module such as an SH2 domain...

The C-terminus of CIS defines its interaction pattern

Lavens, Delphine, Ulrichts, Peter, Catteeuw, Dominiek, Gevaert, Kris, Vandekerckhove, Joël, Peelman, Frank, ...

Proteins of the SOCS (suppressors of cytokine signalling) family are characterized by a conserved modular structure with pre-SH2 (Src homology 2), SH2 and SOCS-box domains. Several members, including...