WILLIAMS, PAUL L., SABLE, DAVID L., SORGEN, STEVEN P., PAPPAGIANIS, DEMOSTHENES, LEVINE, H. B., BRODINE, STEPHANIE K., ...
A trial of the killed Coccidioides immitis spherule vaccine was undertaken with 151 healthy skin test negative adult volunteers and controls to evaluate the safety of selected regimens, the induction...
THE PRESENT STATUS OF VACCINATION AGAINST COCCIDIOIDOMYCOSIS IN MAN (1975)
PAPPAGIANIS, DEMOSTHENES, LEVINE, H. B.
Pappagianis, D. (School of Medicine, U of California, Davis, CA 95616) and H. B. Levine. The present status of vaccination against coccidioidomycosis in man. Am J Epidemiol 102:30–41,...
Thesis (Ph. D. in Bacteriology)--University of California, Berkeley, Jan. 1956.
Factors associated with virulence of Coccidioides immitis. (1956)
Thesis (Ph. D. in Bacteriology)--Univ. of California, Berkeley, Jan. 1956.
Comparison of Fluconazole and Itraconazole in a Rabbit Model of Coccidioidal Meningitis
Sorensen, Kevin N., Sobel, Raymond A., Clemons, Karl V., Pappagianis, Demosthenes, Stevens, David A., Williams, Paul L.
Coccidioidal meningitis is a devastating disease that requires long-term therapy with little hope of cure. A rabbit model of coccidioidal meningitis was used to compare the therapeutic efficacies of...
Sorensen, Kevin N., Sobel, Raymond A., Clemons, Karl V., Calderon, Leilani, Howell, Kimberley J., Irani, Plomarz R., ...
A rabbit model of coccidioidal meningitis was used to compare the therapeutic efficacies of terbinafine (TBF) and fluconazole (FCZ). Hydrocortisone acetate-treated New Zealand White male rabbits were...
Protection against Lethal Murine Coccidioidomycosis by a Soluble Vaccine from Spherules
Zimmermann, C. Roger, Johnson, Suzanne M., Martens, Gregory W., White, Andrew G., Zimmer, Barbara L., Pappagianis, Demosthenes
The formaldehyde-killed, whole-spherule vaccine, which is protective against lethal challenge of laboratory animals with Coccidioides immitis, was fractionated. It yielded a soluble, multicomponent,...
Ampel, Neil M., Kramer, Larissa A., Li, Lijin, Carroll, Deborah S., Kerekes, Kathleen M., Johnson, Suzanne M., ...
Measurement of cellular immunity in human coccidioidomycosis has important diagnostic and prognostic implications. The coccidioidin skin test has been the standard for the measurement of this, but it...
Clemons, Karl V., Sobel, Raymond A., Williams, Paul L., Pappagianis, Demosthenes, Stevens, David A.
The efficacy of intravenously administered liposomal amphotericin B (AmBisome [AmBi]) for the treatment of experimental coccidioidal meningitis was compared with those of oral fluconazole (FLC) and...
Detecting Candida albicans in Human Milk
Morrill, Jimi Francis, Pappagianis, Demosthenes, Heinig, M. Jane, Lönnerdal, Bo, Dewey, Kathryn G.
Procedures for diagnosis of mammary candidosis, including laboratory confirmation, are not well defined. Lactoferrin present in human milk can inhibit growth of Candida albicans, thereby limiting the...
Amplification of Coccidioidal DNA in Clinical Specimens by PCR
Johnson, Suzanne M., Simmons, Keira A., Pappagianis, Demosthenes
Coccidioides DNA was amplified from serum by a PCR using coccidioid-specific primers. A 239-bp product was visualized when 10 fg of exogenous coccidioidal DNA was subjected to amplification. This...
Experimental Induction of Anergy to Coccidioidin by Antigens of Coccidioides immitis
Ibrahim, Ali Bin, Pappagianis, Demosthenes
Failure to react to coccidioidin (anergy) often occurs in patients with disseminated coccidioidomycosis. One possible reason may be desensitization by excessive amounts of antigen. This was studied...
Effects of Lysozyme and Chitinase on the Spherules of Coccidioides immitis In Vitro
Collins, Michael, Pappagianis, Demosthenes
Spherules of Coccidioides immitis strain Silveira produced in vitro were treated with chitinase and lysozyme. The walls of merthiolate-killed mature endosporulating spherules were degraded by...
Inhibition by Lysozyme of Growth of the Spherule Phase of Coccidioides immitis In Vitro
Collins, Michael S., Pappagianis, Demosthenes
Development of mature endosporulating spherules from an endospore inoculum was markedly inhibited by human or hen egg-white (HEW) lysozyme at 5 μg/ml. Mature spherules formed in medium containing 5...
Seroincidence of Coccidioidomycosis during Military Desert Training Exercises
Crum, Nancy F., Potter, Mark, Pappagianis, Demosthenes
Coccidioidomycosis is a common fungal infection acquired in the southwestern United States. This is the first study in over 2 decades to determine the seroincidence of Coccidioides immitis infections...
Lactobacillus plantarum, the Cause of “Yeast Spots” on Olives
Vaughn, Reese H., Won, William D., Spencer, Francis B., Pappagianis, Demosthenes, Foda, I. Omar, Krumperman, Paul H.
The Mannose Receptor Mediates the Cellular Immune Response in Human Coccidioidomycosis
Ampel, Neil M., Nelson, Daniel K., Li, Lijin, Dionne, Sara O., Lake, Douglas F., Simmons, Keira A., ...
Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on...
Ampel, Neil M., Nelson, Daniel K., Chavez, Suzette, Naus, Kathryn A., Herman, Amanda B., Li, Lijin, ...
Assessment of the cellular immune response in coccidioidomycosis has epidemiologic and prognostic importance. Measurement of delayed-type hypersensitivity to skin testing has been used in the past to...
Tempest From Tehachapi Takes Toll or Coccidioides Conveyed Aloft and Afar
Pappagianis, Demosthenes, Einstein, Hans
New cases of acute primary coccidioidomycosis in large numbers resulted from a windstorm that blew through Kern County, California, on December 20, 1977. In most of these cases clinically apparent...
Coccidioidomycosis in Northern California—An Outbreak among Archeology Students near Red Bluff
Werner, S. Benson, Pappagianis, Demosthenes
An outbreak of coccidioidomycosis occurred among 39 archeology students in the summer of 1972. The students excavated Indian ruins near Red Bluff in Tehama County, California, 20 miles north of the...
Endemic Coccidioidomycosis in Northern California—An Outbreak in Yolo County
Loofbourow, John C., Pappagianis, Demosthenes, Cooper, Thomas Y.
Endemicity of coccidioidomycosis in Yolo County, outside previously known endemic areas, was confirmed by occurrence of a small epidemic. Eleven cases of clinically apparent coccidioidomycosis...
Comparison of Fluconazole and Itraconazole in a Rabbit Model of Coccidioidal Meningitis
Sorensen, Kevin N., Sobel, Raymond A., Clemons, Karl V., Pappagianis, Demosthenes, Stevens, David A., Williams, Paul L.
Coccidioidal meningitis is a devastating disease that requires long-term therapy with little hope of cure. A rabbit model of coccidioidal meningitis was used to compare the therapeutic efficacies of...
Sorensen, Kevin N., Sobel, Raymond A., Clemons, Karl V., Calderon, Leilani, Howell, Kimberley J., Irani, Plomarz R., ...
A rabbit model of coccidioidal meningitis was used to compare the therapeutic efficacies of terbinafine (TBF) and fluconazole (FCZ). Hydrocortisone acetate-treated New Zealand White male rabbits were...
Protection against Lethal Murine Coccidioidomycosis by a Soluble Vaccine from Spherules
Zimmermann, C. Roger, Johnson, Suzanne M., Martens, Gregory W., White, Andrew G., Zimmer, Barbara L., Pappagianis, Demosthenes
The formaldehyde-killed, whole-spherule vaccine, which is protective against lethal challenge of laboratory animals with Coccidioides immitis, was fractionated. It yielded a soluble, multicomponent,...
Ampel, Neil M., Kramer, Larissa A., Li, Lijin, Carroll, Deborah S., Kerekes, Kathleen M., Johnson, Suzanne M., ...
Measurement of cellular immunity in human coccidioidomycosis has important diagnostic and prognostic implications. The coccidioidin skin test has been the standard for the measurement of this, but it...
Clemons, Karl V., Sobel, Raymond A., Williams, Paul L., Pappagianis, Demosthenes, Stevens, David A.
The efficacy of intravenously administered liposomal amphotericin B (AmBisome [AmBi]) for the treatment of experimental coccidioidal meningitis was compared with those of oral fluconazole (FLC) and...
Detecting Candida albicans in Human Milk
Morrill, Jimi Francis, Pappagianis, Demosthenes, Heinig, M. Jane, Lönnerdal, Bo, Dewey, Kathryn G.
Procedures for diagnosis of mammary candidosis, including laboratory confirmation, are not well defined. Lactoferrin present in human milk can inhibit growth of Candida albicans, thereby limiting the...
Amplification of Coccidioidal DNA in Clinical Specimens by PCR
Johnson, Suzanne M., Simmons, Keira A., Pappagianis, Demosthenes
Coccidioides DNA was amplified from serum by a PCR using coccidioid-specific primers. A 239-bp product was visualized when 10 fg of exogenous coccidioidal DNA was subjected to amplification. This...
Experimental Induction of Anergy to Coccidioidin by Antigens of Coccidioides immitis
Ibrahim, Ali Bin, Pappagianis, Demosthenes
Failure to react to coccidioidin (anergy) often occurs in patients with disseminated coccidioidomycosis. One possible reason may be desensitization by excessive amounts of antigen. This was studied...
Effects of Lysozyme and Chitinase on the Spherules of Coccidioides immitis In Vitro
Collins, Michael, Pappagianis, Demosthenes
Spherules of Coccidioides immitis strain Silveira produced in vitro were treated with chitinase and lysozyme. The walls of merthiolate-killed mature endosporulating spherules were degraded by...
Inhibition by Lysozyme of Growth of the Spherule Phase of Coccidioides immitis In Vitro
Collins, Michael S., Pappagianis, Demosthenes
Development of mature endosporulating spherules from an endospore inoculum was markedly inhibited by human or hen egg-white (HEW) lysozyme at 5 μg/ml. Mature spherules formed in medium containing 5...
Seroincidence of Coccidioidomycosis during Military Desert Training Exercises
Crum, Nancy F., Potter, Mark, Pappagianis, Demosthenes
Coccidioidomycosis is a common fungal infection acquired in the southwestern United States. This is the first study in over 2 decades to determine the seroincidence of Coccidioides immitis infections...
Lactobacillus plantarum, the Cause of “Yeast Spots” on Olives
Vaughn, Reese H., Won, William D., Spencer, Francis B., Pappagianis, Demosthenes, Foda, I. Omar, Krumperman, Paul H.
The Mannose Receptor Mediates the Cellular Immune Response in Human Coccidioidomycosis
Ampel, Neil M., Nelson, Daniel K., Li, Lijin, Dionne, Sara O., Lake, Douglas F., Simmons, Keira A., ...
Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on...
Ampel, Neil M., Nelson, Daniel K., Chavez, Suzette, Naus, Kathryn A., Herman, Amanda B., Li, Lijin, ...
Assessment of the cellular immune response in coccidioidomycosis has epidemiologic and prognostic importance. Measurement of delayed-type hypersensitivity to skin testing has been used in the past to...
Tempest From Tehachapi Takes Toll or Coccidioides Conveyed Aloft and Afar
Pappagianis, Demosthenes, Einstein, Hans
New cases of acute primary coccidioidomycosis in large numbers resulted from a windstorm that blew through Kern County, California, on December 20, 1977. In most of these cases clinically apparent...
Coccidioidomycosis in Northern California—An Outbreak among Archeology Students near Red Bluff
Werner, S. Benson, Pappagianis, Demosthenes
An outbreak of coccidioidomycosis occurred among 39 archeology students in the summer of 1972. The students excavated Indian ruins near Red Bluff in Tehama County, California, 20 miles north of the...
Endemic Coccidioidomycosis in Northern California—An Outbreak in Yolo County
Loofbourow, John C., Pappagianis, Demosthenes, Cooper, Thomas Y.
Endemicity of coccidioidomycosis in Yolo County, outside previously known endemic areas, was confirmed by occurrence of a small epidemic. Eleven cases of clinically apparent coccidioidomycosis...