Cancer chemoprevention by the antioxidant tempol acts partially via the p53 tumor suppressor (2005)
Erker, Laura, Schubert, Ralf, Yakushiji, Hiroyuki, Barlow, Carrolee, Larson, Denise, Mitchell, James B., ...
We previously demonstrated that the nitroxide antioxidant tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl) increased latency to tumorigenesis and doubled (100%) the lifespan of...
Cancer chemoprevention by the antioxidant Tempol in Atm-deficient mice (2004)
Schubert, Ralf, Erker, Laura, Barlow, Carrolee, Yakushiji, Hiroyuki, Larson, Denise, Russo, Angelo, ...
Reactive oxygen species (ROS) are important endogenous etiological agents for DNA damage, and ROS perform critical signaling functions in apoptosis, stress responses and proliferation. The...
Cancer chemoprevention by the antioxidant tempol in Atm-deficient mice (2004)
Schubert, Ralf, Erker, Laura, Barlow, Carrolee, Yakushiji, Hiroyuki, Larson, Denise, Russo, Angelo, ...
Reactive oxygen species (ROS) are important endogenous etiological agents for DNA damage, and ROS perform critical signaling functions in apoptosis, stress responses and proliferation. The...
Cancer chemoprevention by the antioxidant Tempol in Atm-deficient mice (2004)
Schubert, Ralf, Erker, Laura, Barlow, Carrolee, Yakushiji, Hiroyuki, Larson, Denise, Russo, Angelo, ...
Reactive oxygen species (ROS) are important endogenous etiological agents for DNA damage, and ROS perform critical signaling functions in apoptosis, stress responses and proliferation. The...
Karabinis, Melissa E., Larson, Denise, Barlow, Carrolee, Wynshaw-Boris, Anthony, Moser, Amy Rapaich
The proteins encoded by BRCA1 and ATM may be important in DNA repair and maintenance of genomic integrity. Women heterozygous for a mutation in BRCA1 have an increased incidence of breast cancer....
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. (2000)
Barlow, Carrolee, Ribaut-Barassin, Catherine, Zwingman, Theresa A., Pope, Amber J., Brown, Kevin D., Owens, Jennie W., ...
We previously generated a mouse model with a mutation in the murine Atm gene that recapitulates many aspects of the childhood neurodegenerative disease ataxia-telangiectasia. Atm-deficient (Atm-/-)...
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation
Barlow, Carrolee, Ribaut-Barassin, Catherine, Zwingman, Theresa A., Pope, Amber J., Brown, Kevin D., Owens, Jennie W., ...
We previously generated a mouse model with a mutation in the murine Atm gene that recapitulates many aspects of the childhood neurodegenerative disease ataxia-telangiectasia. Atm-deficient...
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation
Barlow, Carrolee, Ribaut-Barassin, Catherine, Zwingman, Theresa A., Pope, Amber J., Brown, Kevin D., Owens, Jennie W., ...
We previously generated a mouse model with a mutation in the murine Atm gene that recapitulates many aspects of the childhood neurodegenerative disease ataxia-telangiectasia. Atm-deficient...