Estimating node degree in bait-prey graphs (2008)
Denise Scholtens, Tony Chiang, Wolfgang Huber
Motivation: Proteins work together to drive biological processes in cellular machines. Summarizing global and local properties of the set of protein interactions, the interactome, is necessary for...
Estimating node degree in bait-prey graphs (2008)
Scholtens, Denise, Chiang, Tony, Huber, Wolfgang, Gentleman, Robert
Motivation: Proteins work together to drive biological processes in cellular machines. Summarizing global and local properties of the set of protein interactions, the interactome, is necessary for...
Coverage and error models of protein-protein interaction data by directed graph analysis (2007)
Chiang, Tony, Scholtens, Denise, Sarkar, Deepayan, Gentleman, Robert, Huber, Wolfgang
Abstract Using a directed graph model for bait to prey systems and a multinomial error model, we assessed the error statistics in all published large-scale datasets for Saccharomyces cerevisiae and...
Associations of Microarray Analysis Results with Gene Ontology Annotation (2007)
In this lab we will explore the use of Gene Ontology (GO) to note particular associations with the results of microarray data analyses. In particular, we will compare and contrast the output of
Making Sense of High-Throughput Protein-Protein Interaction Data (2005)
Scholtens, Denise, Gentleman, Robert
Accurate systems biology modeling requires a complete catalog of protein complexes and their constituent proteins. We discuss a graph-theoretic/statistical algorithm for local dynamic modeling of...
Making Sense of High-Throughput Protein-Protein Interaction Data (2005)
Scholtens, Denise, Gentleman, Robert
Accurate systems biology modeling requires a complete catalog of protein complexes and their constituent proteins. We discuss a graph-theoretic/statistical algorithm for local dynamic modeling of...
Making Sense of High-Throughput Protein-Protein Interaction Data (2005)
Scholtens, Denise, Gentleman, Robert
Accurate systems biology modeling requires a complete catalog of protein complexes and their constituent proteins. We discuss a graph-theoretic/statistical algorithm for local dynamic modeling of...
Making Sense of High-Throughput Protein-Protein Interaction Data (2005)
Scholtens, Denise, Gentleman, Robert
Accurate systems biology modeling requires a complete catalog of protein complexes and their constituent proteins. We discuss a graph-theoretic/statistical algorithm for local dynamic modeling of...
BIOINFORMATICS ORIGINAL PAPER Systems biology Local modeling of global interactome networks (2005)
Denise Scholtens, Marc Vidal, Robert Gentleman
Motivation: Systems biology requires accurate models of protein complexes, including physical interactions that assemble and regulate these molecular machines. Yeast two-hybrid (Y2H) and affinity–...
Local modeling of global interactome networks (2005)
Scholtens, Denise, Vidal, Marc, Gentleman, Robert
Motivation: Systems biology requires accurate models of protein complexes, including physical interactions that assemble and regulate these molecular machines. Yeast two-hybrid (Y2H) and...
Local modeling of global interactome networks (2005)
Scholtens, Denise, Vidal, Marc, Gentleman, Robert
Motivation: Systems biology requires accurate models of protein complexes, including physical interactions that assemble and regulate these molecular machines. Yeast two-hybrid (Y2H) and...
Balasubramanian, Raji, LaFramboise, Thomas, Scholtens, Denise, Gentleman, Robert
The last few years have seen the advent of high-throughput technologies to analyze various properties of the transcriptome and proteome of several organisms. The congruency of these different data...
Balasubramanian, Raji, LaFramboise, Thomas, Scholtens, Denise, Gentleman, Robert
The last few years have seen the advent of high-throughput technologies to analyze various properties of the transcriptome and proteome of several organisms. The congruency of these different data...
Balasubramanian, Raji, LaFramboise, Thomas, Scholtens, Denise, Gentleman, Robert
The last few years have seen the advent of high-throughput technologies to analyze various properties of the transcriptome and proteome of several organisms. The congruency of these different data...
Balasubramanian, Raji, LaFramboise, Thomas, Scholtens, Denise, Gentleman, Robert
The last few years have seen the advent of high-throughput technologies to analyze various properties of the transcriptome and proteome of several organisms. The congruency of these different data...
Balasubramanian, Raji, LaFramboise, Thomas, Scholtens, Denise, Gentleman, Robert
Motivation: The last few years have seen the advent of high-throughput technologies to analyze various properties of the transcriptome and proteome of several organisms. The congruency of these...
Balasubramanian, Raji, LaFramboise, Thomas, Scholtens, Denise, Gentleman, Robert
Motivation: The last few years have seen the advent of high-throughput technologies to analyze various properties of the transcriptome and proteome of several organisms. The congruency of these...
Balasubramanian, Raji, LaFramboise, Thomas, Scholtens, Denise, Gentleman, Robert
Motivation: The last few years have seen the advent of high-throughput technologies to analyze various properties of the transcriptome and proteome of several organisms. The congruency of these...
Making Sense of High-Throughput Protein-Protein Interaction Data
Denise Scholtens, Robert Gentleman
Accurate systems biology modeling requires a complete catalog of protein complexes and their constituent proteins. We discuss a graph-theoretic/statistical algorithm for local dynamic modeling of...
Coverage and error models of protein-protein interaction data by directed graph analysis
Chiang, Tony, Scholtens, Denise, Sarkar, Deepayan, Gentleman, Robert, Huber, Wolfgang
Directed graph and multinomial error models were used to assess and characterize the error statistics in all published large-scale datasets for Saccharomyces cerevisiae
Analyzing factorial designed microarray experiments
Scholtens, Denise, Miron, Alexander, M. Merchant, Faisal, Miller, Arden, L. Miron, Penelope, Dirk Iglehart, J., ...
High-throughput quantification of gene expression using microarray technology has dramatically changed biological investigation into the roles of genes in normal cell functioning, as well as the...