Diane G. Newell

Publication List Details

Period

2000 - 2006

Number

33

Co-Authors

The galE gene of Campylobacter jejuni is involved in LPS synthesis and virulence: (2000)

Fry, Ben, Feng, Shi, Chen, Yuen-Yuen, Newell, Diane G., Coloe, Peter, Korolik, Victoria

Lipopolysaccharide (LPS) is one of the main virulence factors of gram-negative bacteria. The LPS from Campylobacter spp. has endotoxic properties and has been shown to play a role in adhesion. We...

The galE gene of Campylobacter jejuni is involved in LPS synthesis and virulence: (2000)

Fry, Ben, Feng, Shi, Chen, Yuen-Yuen, Newell, Diane G., Coloe, Peter, Korolik, Victoria

Lipopolysaccharide (LPS) is one of the main virulence factors of gram-negative bacteria. The LPS from Campylobacter spp. has endotoxic properties and has been shown to play a role in adhesion. We...

The galE gene of Campylobacter jejuni is involved in LPS synthesis and virulence: (2000)

Fry, Ben, Feng, Shi, Chen, Yuen-Yuen, Newell, Diane G., Coloe, Peter, Korolik, Victoria

Lipopolysaccharide (LPS) is one of the main virulence factors of gram-negative bacteria. The LPS from Campylobacter spp. has endotoxic properties and has been shown to play a role in adhesion. We...

The galE gene of Campylobacter jejuni is involved in LPS synthesis and virulence: (2000)

Fry, Ben, Feng, Shi, Chen, Yuen-Yuen, Newell, Diane G., Coloe, Peter, Korolik, Victoria

Lipopolysaccharide (LPS) is one of the main virulence factors of gram-negative bacteria. The LPS from Campylobacter spp. has endotoxic properties and has been shown to play a role in adhesion. We...

Comparative Study Using Amplified Fragment Length Polymorphism Fingerprinting, PCR Genotyping, and Phenotyping To Differentiate Campylobacter fetus Strains Isolated from Animals

Wagenaar, Jaap A., Newell, Diane G., Grogono-Thomas, Rose, Duim, Birgitta

A collection of Campylobacter fetus strains, including both C. fetus subsp. fetus and C. fetus subsp. venerealis, were phenotypically identified to the subspecies level and genotypically typed by PCR...

Generation of a Superoxide Dismutase (SOD)-Deficient Mutant of Campylobacter coli: Evidence for the Significance of SOD in Campylobacter Survival and Colonization

Purdy, Desmond, Cawthraw, Sean, Dickinson, Joanne H., Newell, Diane G., Park, Simon F.

The microaerophilic nature of Campylobacter species implies an inherent sensitivity towards oxygen and its reduction products, particularly the superoxide anion. The deleterious effects of exposure...

A Novel Campylobacter jejuni Two-Component Regulatory System Important for Temperature-Dependent Growth and Colonization

Brás, Ana M., Chatterjee, Shimonti, Wren, Brendan W., Newell, Diane G., Ketley, Julian M.

Campylobacter jejuni colonizes the intestines of domestic and wild animals and is a common cause of human diarrheal disease. We identified a two-component regulatory system, designated the RacR-RacS...

The galE Gene of Campylobacter jejuni Is Involved in Lipopolysaccharide Synthesis and Virulence

Fry, Benjamin N., Feng, Shi, Chen, Yuen-Yuen, Newell, Diane G., Coloe, Peter J., Korolik, Victoria

Lipopolysaccharide (LPS) is one of the main virulence factors of gram-negative bacteria. The LPS from Campylobacter spp. has endotoxic properties and has been shown to play a role in adhesion. We...

Campylobacter fetus sap Inversion Occurs in the Absence of RecA Function

Ray, Kevin C., Tu, Zheng-Chao, Grogono-Thomas, Rosemary, Newell, Diane G., Thompson, Stuart A., Blaser, Martin J.

Phase variation of Campylobacter fetus surface layer proteins (SLPs) occurs by inversion of a 6.2-kb DNA segment containing the unique sap promoter, permitting expression of a single SLP-encoding...

Evidence of Genomic Instability in Campylobacter jejuni Isolated from Poultry

Wassenaar, Trudy M., Geilhausen, Barbara, Newell, Diane G.

Poultry isolates of Campylobacter jejuni derived from a survey of meat processing batches were genotyped by pulsed-field gel electrophoresis (PFGE) of chromosomal DNA to establish the clonal...

Multilocus Sequence Typing for Comparison of Veterinary and Human Isolates of Campylobacter jejuni

Manning, Georgina, Dowson, Christopher G., Bagnall, Mary C., Ahmed, If H., West, Malcolm, Newell, Diane G.

Multilocus sequence typing (MLST) has been applied to 266 Campylobacter jejuni isolates, mainly from veterinary sources, including cattle, sheep, poultry, pigs, pets, and the environment, as well as...

The Genome-Sequenced Variant of Campylobacter jejuni NCTC 11168 and the Original Clonal Clinical Isolate Differ Markedly in Colonization, Gene Expression, and Virulence-Associated Phenotypes

Gaynor, Erin C., Cawthraw, Shaun, Manning, Georgina, MacKichan, Joanna K., Falkow, Stanley, Newell, Diane G.

The genome sequence of the enteric bacterial pathogen Campylobacter jejuni NCTC 11168 (11168-GS) was published in 2000, providing a valuable resource for the identification of C. jejuni-specific...

Cytolethal Distending Toxin (CDT)-Negative Campylobacter jejuni Strains and Anti-CDT Neutralizing Antibodies Are Induced during Human Infection but Not during Colonization in Chickens

AbuOun, Manal, Manning, Georgina, Cawthraw, Shaun A., Ridley, Anne, Ahmed, If H., Wassenaar, Trudy M., ...

The cytolethal distending toxin (CDT) of Campylobacter jejuni was detectable, using an in vitro assay, in most but not all of 24 strains tested. The reason for the absence of toxin activity in these...

Application of Fluorescent Amplified Fragment Length Polymorphism for Comparison of Human and Animal Isolates of Yersinia enterocolitica

Fearnley, Catherine, On, Stephen L. W., Kokotovic, Branko, Manning, Georgina, Cheasty, Tom, Newell, Diane G.

An amplified fragment length polymorphism (AFLP) method, developed to genotype Yersinia enterocolitica, has been used to investigate 70 representative strains isolated from humans, pigs, sheep, and...

Clonal Nature of Campylobacter fetus as Defined by Multilocus Sequence Typing

Dingle, Kate E., Maiden, Martin C. J., Newell, Diane G., ...

Campylobacter fetus can be divided into the subspecies C. fetus subsp. fetus and C. fetus subsp. venerealis. C. fetus subsp. fetus causes sporadic infections in humans and abortion in cattle and...

Comparative Study Using Amplified Fragment Length Polymorphism Fingerprinting, PCR Genotyping, and Phenotyping To Differentiate Campylobacter fetus Strains Isolated from Animals

Wagenaar, Jaap A., Newell, Diane G., Grogono-Thomas, Rose, Duim, Birgitta

A collection of Campylobacter fetus strains, including both C. fetus subsp. fetus and C. fetus subsp. venerealis, were phenotypically identified to the subspecies level and genotypically typed by PCR...

Generation of a Superoxide Dismutase (SOD)-Deficient Mutant of Campylobacter coli: Evidence for the Significance of SOD in Campylobacter Survival and Colonization

Purdy, Desmond, Cawthraw, Sean, Dickinson, Joanne H., Newell, Diane G., Park, Simon F.

The microaerophilic nature of Campylobacter species implies an inherent sensitivity towards oxygen and its reduction products, particularly the superoxide anion. The deleterious effects of exposure...

A Novel Campylobacter jejuni Two-Component Regulatory System Important for Temperature-Dependent Growth and Colonization

Brás, Ana M., Chatterjee, Shimonti, Wren, Brendan W., Newell, Diane G., Ketley, Julian M.

Campylobacter jejuni colonizes the intestines of domestic and wild animals and is a common cause of human diarrheal disease. We identified a two-component regulatory system, designated the RacR-RacS...

The galE Gene of Campylobacter jejuni Is Involved in Lipopolysaccharide Synthesis and Virulence

Fry, Benjamin N., Feng, Shi, Chen, Yuen-Yuen, Newell, Diane G., Coloe, Peter J., Korolik, Victoria

Lipopolysaccharide (LPS) is one of the main virulence factors of gram-negative bacteria. The LPS from Campylobacter spp. has endotoxic properties and has been shown to play a role in adhesion. We...

Campylobacter fetus sap Inversion Occurs in the Absence of RecA Function

Ray, Kevin C., Tu, Zheng-Chao, Grogono-Thomas, Rosemary, Newell, Diane G., Thompson, Stuart A., Blaser, Martin J.

Phase variation of Campylobacter fetus surface layer proteins (SLPs) occurs by inversion of a 6.2-kb DNA segment containing the unique sap promoter, permitting expression of a single SLP-encoding...

Evidence of Genomic Instability in Campylobacter jejuni Isolated from Poultry

Wassenaar, Trudy M., Geilhausen, Barbara, Newell, Diane G.

Poultry isolates of Campylobacter jejuni derived from a survey of meat processing batches were genotyped by pulsed-field gel electrophoresis (PFGE) of chromosomal DNA to establish the clonal...

Multilocus Sequence Typing for Comparison of Veterinary and Human Isolates of Campylobacter jejuni

Manning, Georgina, Dowson, Christopher G., Bagnall, Mary C., Ahmed, If H., West, Malcolm, Newell, Diane G.

Multilocus sequence typing (MLST) has been applied to 266 Campylobacter jejuni isolates, mainly from veterinary sources, including cattle, sheep, poultry, pigs, pets, and the environment, as well as...

The Genome-Sequenced Variant of Campylobacter jejuni NCTC 11168 and the Original Clonal Clinical Isolate Differ Markedly in Colonization, Gene Expression, and Virulence-Associated Phenotypes

Gaynor, Erin C., Cawthraw, Shaun, Manning, Georgina, MacKichan, Joanna K., Falkow, Stanley, Newell, Diane G.

The genome sequence of the enteric bacterial pathogen Campylobacter jejuni NCTC 11168 (11168-GS) was published in 2000, providing a valuable resource for the identification of C. jejuni-specific...

Cytolethal Distending Toxin (CDT)-Negative Campylobacter jejuni Strains and Anti-CDT Neutralizing Antibodies Are Induced during Human Infection but Not during Colonization in Chickens

AbuOun, Manal, Manning, Georgina, Cawthraw, Shaun A., Ridley, Anne, Ahmed, If H., Wassenaar, Trudy M., ...

The cytolethal distending toxin (CDT) of Campylobacter jejuni was detectable, using an in vitro assay, in most but not all of 24 strains tested. The reason for the absence of toxin activity in these...

Application of Fluorescent Amplified Fragment Length Polymorphism for Comparison of Human and Animal Isolates of Yersinia enterocolitica

Fearnley, Catherine, On, Stephen L. W., Kokotovic, Branko, Manning, Georgina, Cheasty, Tom, Newell, Diane G.

An amplified fragment length polymorphism (AFLP) method, developed to genotype Yersinia enterocolitica, has been used to investigate 70 representative strains isolated from humans, pigs, sheep, and...

Clonal Nature of Campylobacter fetus as Defined by Multilocus Sequence Typing

Dingle, Kate E., Maiden, Martin C. J., Newell, Diane G., ...

Campylobacter fetus can be divided into the subspecies C. fetus subsp. fetus and C. fetus subsp. venerealis. C. fetus subsp. fetus causes sporadic infections in humans and abortion in cattle and...

Development of a Strain-Specific Molecular Method for Quantitating Individual Campylobacter Strains in Mixed Populations▿

Elvers, Karen T., Helps, Christopher R., Wassenaar, Trudy M., Allen, Vivien M., Newell, Diane G.

The identification of sites resulting in cross-contamination of poultry flocks in the abattoir and determination of the survival and persistence of campylobacters at these sites are essential for the...

Real-Time PCR Approach for Detection of Environmental Sources of Campylobacter Strains Colonizing Broiler Flocks▿

Ridley, Anne M., Allen, Vivien M., Sharma, Meenaxi, Harris, Jill A., Newell, Diane G.

Reducing colonization of poultry flocks by Campylobacter spp. is a key strategy in the control and prevention human campylobacteriosis. Horizontal transmission of campylobacters, from in and around...