Diane J. Burgess

Controlled Release of Dexamethasone from PLGA Microspheres Embedded Within Polyacid-Containing PVA Hydrogels (2008)

Izabela Galeska, Tae-kyoung Kim, Siddhesh D. Patil, Upkar Bhardwaj, Debjit Chatttopadhyay, Fotios Papadimitrakopoulos, ...

The development of zero-order release systems capable of delivering drug(s) over extended periods of time is deemed necessary for a variety of biomedical applications. We hereby describe a simple,...

Preparation of Drug Delivery Biodegradable PLGA Nanocomposites and Foams by Supercritical COsub2 Expanded Ring Opening Polymerization and by Rapid Expansion from CHCIF2 Supercritical Solutions (2005)

Asandei, Alexandru D., Erkey, Can, Burgess, Diane J., Saquing, Carl, Saha, Gobinda, Zolnik, Banu S.

The synthesis of poly(lactic-co-glycolic acid) (PLGA) by the ring opening copolymerization of D,L-lactide and glycolide was performed at 110 deg C to 130 deg C using Sn(Oct)2 as catalyst,...

Assuring quality and performance of sustained and controlled release parenterals: EUFEPS workshop report

Burgess, Diane J., Crommelin, Daan J. A., Hussain, Ajaz S., Chen, Mei-Ling

This is a summary report of the workshop, organized by the European Federation of Pharmaceutical Scientists in association with the American Association of Pharmaceutical Scientists, the European...

Anionic liposomal delivery system for DNA transfection

Patil, Siddhesh D., Rhodes, David G., Burgess, Diane J.

The present study investigates the use of novel anionic lipoplexes composed of physiological components for plasmid DNA delivery into mammalian cells in vitro. Liposomes were prepared from mixtures...

Particle size analysis: AAPS workshop report, cosponsored by the Food and Drug Administration and the United States Pharmacopeia

Burgess, Diane J., Duffy, Eric, Etzler, Frank, Hickey, Anthony J.

The concepts of particle engineering and dosage form design have become dominant themes in pharmaceutical manufacturing. This trend is not simply a reflection of the development of new, more...

Assuring quality and performance of sustained and controlled release parenterals: Workshop report

Burgess, Diane J., Hussain, Ajaz S., Ingallinera, Thomas S., Chen, Mei-Ling

This is a summary report of the American Association of Pharmaceutical Scientists, the Food and Drug Administration and the United States Pharmacopoeia cosponsored workshop on “Assuring Quality and...

Rheology and stability of water-in-oil-in-water multiple emulsions containing Span 83 and Tween 80

Jiao, Jim, Burgess, Diane J.

Multiple emulsions are often stabilized using a combination of hydrophilic and hydrophobic surfactants. The ratio of these surfactants is important in achieving stable multiple emulsions. The...

DNA-based therapeutics and DNA delivery systems: A comprehensive review

Patil, Siddhesh D., Rhodes, David G., Burgess, Diane J.

The past several years have witnessed the evolution of gene medicine from an experimental technology into a viable strategy for developing therapeutics for a wide range of human disorders. Numerous...

Controlled release of dexamethasone from PLGA microspheres embedded within polyacid-containing PVA hydrogels

Galeska, Izabela, Kim, Tae-Kyoung, Patil, Siddhesh D., Bhardwaj, Upkar, Chatttopadhyay, Debjit, Papadimitrakopoulos, Fotios, ...

The development of zero-order release systems capable of delivering drug(s) over extended periods of time is deemed necessary for a variety of biomedical applications. We hereby describe a simple,...

Mathematical modeling of surface-active and non-surface-active drug transport in emulsion systems

Chidambaram, Nachiappan, Burgess, Diane J.

Mathematical models were developed for the prediction of surface-active and non- surface-active drug transport in triphasic (oil, water, and micellar) emulsion systems as a function of micellar...

A Review of the Development of a Vehicle for Localized and Controlled Drug Delivery for Implantable Biosensors

Bhardwaj, Upkar, Papadimitrakopoulos, Fotios, Burgess, Diane J.

A major obstacle to the development of implantable biosensors is the foreign body response (FBR) that results from tissue trauma during implantation and the continuous presence of the implant in the...

A Review of the Biocompatibility of Implantable Devices: Current Challenges to Overcome Foreign Body Response

Onuki, Yoshinori, Bhardwaj, Upkar, Papadimitrakopoulos, Fotios, Burgess, Diane J.

In recent years, a variety of devices (drug-eluting stents, artificial organs, biosensors, catheters, scaffolds for tissue engineering, heart valves, etc.) have been developed for implantation into...