Didier Concordet

Comparison of Doppler ultrasonography and high-definition oscillometry for blood pressure measurements in healthy awake dogs. (2010)

Chetboul, Valérie, Tissier, Renaud, Gouni, Vassiliki, De Almeida, Virginie, Lefebvre, Hervé, Concordet, Didier, ...

OBJECTIVE: To determine the intra- and interobserver variability of systolic arterial pressure (SAP) and diastolic arterial pressure (DAP) measurements obtained with 2 indirect methods in awake dogs...

Comparison of Doppler ultrasonography and high-definition oscillometry for blood pressure measurements in healthy awake dogs. (2010)

Chetboul, Valérie, Tissier, Renaud, Gouni, Vassiliki, De Almeida, Virginie, Lefebvre, Hervé, Concordet, Didier, ...

OBJECTIVE: To determine the intra- and interobserver variability of systolic arterial pressure (SAP) and diastolic arterial pressure (DAP) measurements obtained with 2 indirect methods in awake dogs...

Comparison of Doppler ultrasonography and high-definition oscillometry for blood pressure measurements in healthy awake dogs. (2010)

Chetboul, Valérie, Tissier, Renaud, Gouni, Vassiliki, De Almeida, Virginie, Lefebvre, Hervé, Concordet, Didier, ...

OBJECTIVE: To determine the intra- and interobserver variability of systolic arterial pressure (SAP) and diastolic arterial pressure (DAP) measurements obtained with 2 indirect methods in awake dogs...

Confidence regions for the multinomial parameter with small sample size (2009)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M(n,p) where p is an unknown...

Confidence regions for the multinomial parameter with small sample size (2009)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M(n,p) where p is an unknown...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2009)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2009)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

Comparison of nonparametric methods in nonlinear mixed effects models (2009)

Antic, Julie, Laffont, Céline, Chafai, Djalil, Concordet, Didier

During the drug development, nonlinear mixed effects models are routinely used to study the drug's pharmacokinetics and pharmacodynamics. The distribution of random effects is of special interest...

Comparison of nonparametric methods in nonlinear mixed effects models (2009)

Antic, Julie, Laffont, Céline, Chafai, Djalil, Concordet, Didier

During the drug development, nonlinear mixed effects models are routinely used to study the drug's pharmacokinetics and pharmacodynamics. The distribution of random effects is of special interest...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2009)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2009)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

Comparison of nonparametric methods in nonlinear mixed effects models (2009)

Antic, Julie, Laffont, Céline, Chafai, Djalil, Concordet, Didier

During the drug development, nonlinear mixed effects models are routinely used to study the drug's pharmacokinetics and pharmacodynamics. The distribution of random effects is of special interest...

Comparison of nonparametric methods in nonlinear mixed effects models (2009)

Antic, Julie, Laffont, Céline, Chafai, Djalil, Concordet, Didier

During the drug development, nonlinear mixed effects models are routinely used to study the drug's pharmacokinetics and pharmacodynamics. The distribution of random effects is of special interest...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2009)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

Confidence regions for the multinomial parameter with small sample size (2009)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M(n,p) where p is an unknown...

Comparison of nonparametric methods in nonlinear mixed effects models (2009)

Antic, Julie, Laffont, Céline, Chafai, Djalil, Concordet, Didier

During the drug development, nonlinear mixed effects models are routinely used to study the drug's pharmacokinetics and pharmacodynamics. The distribution of random effects is of special interest...

STATISTICS IN MEDICINE (2008)

Cecile Ane, Didier Concordet, John Wiley

Population pharmacokinetics=pharmacodynamics relationships of an anticancer drug

Explicit formulas for a continuous stochastic maturation model. Application to anticancer drug pharmacokinetics/pharmacodynamics. (2008)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

Explicit formulas for a continuous stochastic maturation model. Application to anticancer drug pharmacokinetics/pharmacodynamics. (2008)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2008)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2008)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

Confidence regions for the multinomial parameter with small sample size (2008)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M_d(n,p) where p is an unknown...

Confidence regions for the multinomial parameter with small sample size (2008)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M_d(n,p) where p is an unknown...

Confidence regions for the multinomial parameter with small sample size (2008)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M(n,p) where p is an unknown...

Explicit formulas for a continuous stochastic maturation model. Application to anticancer drug pharmacokinetics/pharmacodynamics. (2008)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

Explicit formulas for a continuous stochastic maturation model. Application to anticancer drug pharmacokinetics/pharmacodynamics. (2008)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

Comparison of nonparametric methods in nonlinear mixed effects models (2008)

Antic, Julie, Laffont, Céline, Chafai, Djalil, Concordet, Didier

During the drug development, nonlinear mixed effects models are routinely used to study the drug's pharmacokinetics and pharmacodynamics. The distribution of random effects is of special interest...

Comparison of nonparametric methods in nonlinear mixed effects models (2008)

Antic, Julie, Laffont, Céline, Chafai, Djalil, Concordet, Didier

During the drug development, nonlinear mixed effects models are routinely used to study the drug's pharmacokinetics and pharmacodynamics. The distribution of random effects is of special interest...

Confidence regions for the multinomial parameter with small sample size (2008)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M(n,p) where p is an unknown...

Confidence regions for the multinomial parameter with small sample size (2008)

Chafai, Djalil, Concordet, Didier

Consider the observation of n iid realizations of an experiment with d>1 possible outcomes, which corresponds to a single observation of a multinomial distribution M(n,p) where p is an unknown...

Explicit formulas for a continuous stochastic maturation model. Application to anticancer drug pharmacokinetics/pharmacodynamics. (2008)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

A new method for the estimation of variance matrix with prescribed zeros in nonlinear mixed effects models (2007)

Chafai, Djalil, Concordet, Didier

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The...

On the strong consistency of asymptotic M-estimators (2007)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

On the strong consistency of asymptotic M-estimators (2007)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

On the strong consistency of asymptotic M-estimators (2007)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

On the strong consistency of asymptotic M-estimators (2007)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

On the strong consistency of asymptotic M-estimators (2007)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

A continuous stochastic maturation model (2006)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

A continuous stochastic maturation model (2006)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

On the strong consistency of asymptotic M-estimators (2005)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

On the strong consistency of approximated M-estimators (2005)

Chafai, Djalil, Concordet, Didier

The aim of this article is to provide a strong consistency Theorem for approximated M-estimators. It contains both Wald and Pfanzagl type results for maximum likelihood. The proof relies, in...

On the strong consistency of asymptotic M-estimators (2005)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

On the strong consistency of asymptotic M-estimators (2005)

Chafai, Djalil, Concordet, Didier

The aim of this article is to simplify Pfanzagl's proof of consistency for asymptotic maximum likelihood estimators, and to extend it to more general asymptotic M-estimators. The method relies on the...

A continuous stochastic maturation model (2004)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

A continuous stochastic maturation model (2004)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

A continuous stochastic maturation model (2004)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...

Explicit formulas for a continuous stochastic maturation model. Application to anticancer drug pharmacokinetics/pharmacodynamics (2004)

Chafai, Djalil, Concordet, Didier

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular...