Domazet-Lošo, Tomislav, Tautz, Diethard
Abstract Background Phylostratigraphy is a method used to correlate the evolutionary origin of founder genes (that is, functional founder protein domains) of gene families with particular...
Understanding the onset of hybrid speciation (2010)
Nolte, Arne W., Tautz, Diethard
Natural hybridization between closely related taxa is a common phenomenon in both plants and animals. Hybridization has often been viewed as a destructive force that could erode established gene...
Wolf, Jochen B. W., Bayer, Till, Haubold, Bernhard, Schilhabel, Markus, Rosenstiel, Philip, Tautz, Diethard
Recent advances in sequencing technology promise to provide new strategies for studying population differentiation and speciation phenomena in their earliest phases. We focus here on the black...
Domazet-Lošo, Tomislav, Tautz, Diethard
Background: Phylostratigraphy is a method used to correlate the evolutionary origin of founder genes (that is, functional founder protein domains) of gene families with particular macroevolutionary...
Copy Number Changes of CNV Regions in Intersubspecific Crosses of the House Mouse (2010)
Scavetta, Rick J., Tautz, Diethard
Copy number variation (CNV) contributes significantly to natural genetic variation within and between populations. However, the mutational mechanisms leading to CNV, as well as the processes that...
Ulf Dieckmann, Diethard Tautz, Michael Doebeli
examined the diversity of beetles that lived on a single species of tropical trees, he found 682 different beetle species, 163 of which he classified as specialist species that lived exclusively on...
The root of the East African cichlid radiations (2009)
Schwarzer, Julia, Misof, Bernhard, Tautz, Diethard, Schliewen, Ulrich K
Abstract Background For decades cichlid fishes (Perciformes: Cichlidae) of the East African cichlid radiations (Teleostei: Cichlidae) have served as natural experimental subjects for the study of...
Johnsen, Jill M., Teschke, Meike, Pavlidis, Pavlos, McGee, Beth M., Tautz, Diethard, Ginsburg, David, ...
The RIIIS/J inbred mouse strain is a model for type 1 von Willebrand disease (VWD), a common human bleeding disorder. Low von Willebrand factor (VWF) levels in RIIIS/J are due to a regulatory...
Polycistronic peptide coding genes in eukaryotes - how widespread are they? (2009)
The classical textbook assumption for the structure of an eukaryotic gene is that it codes for a single polypeptide of more than 100 amino acids in length. This is also the implicit assumption in...
Polycistronic peptide coding genes in eukaryotes--how widespread are they? (2009)
The classical textbook assumption for the structure of an eukaryotic gene is that it codes for a single polypeptide of more than 100 amino acids in length. This is also the implicit assumption in...
Johnsen, Jill M., Teschke, Meike, Pavlidis, Pavlos, McGee, Beth M., Tautz, Diethard, Ginsburg, David, ...
The RIIIS/J inbred mouse strain is a model for type 1 von Willebrand disease (VWD), a common human bleeding disorder. Low von Willebrand factor (VWF) levels in RIIIS/J are due to a regulatory...
Emergence of a new gene from an intergenic region (2009)
Staubach, Fabian, Häming, Daniela, Tautz, Diethard
It is generally assumed that new genes would arise by gene duplication mechanisms, because the signals for regulation and transcript processing would be unlikely to evolve in parallel with a new gene...
The root of the East African cichlid radiations (2009)
Schwarzer, Julia, Misof, Bernhard, Tautz, Diethard, Schliewen, Ulrich K.
Background: For decades cichlid fishes (Perciformes: Cichlidae) of the East African cichlid radiations (Teleostei: Cichlidae) have served as natural experimental subjects for the study of speciation...
Staubach, Fabian, Teschke, Meike, Voolstra, Christian R., Wolf, Jochen B. W., Tautz, Diethard
Changes in expression of genes are thought to contribute significantly to evolutionary divergence. To study the relative role of selection and neutrality in shaping expression changes, we analyzed 24...
Julia Schwarzer, Bernhard Misof, Diethard Tautz, Ulrich K Schliewen, Diethard Tautz, Ulrich K Schliewen
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Wolf, Jochen BW, Harrod, Chris, Brunner, Sylvia, Salazar, Sandie, Trillmich, Fritz, Tautz, Diethard
Abstract Background Oceans are high gene flow environments that are traditionally believed to hamper the build-up of genetic divergence. Despite this, divergence appears to occur occasionally at...
The genome of the model beetle and pest Tribolium castaneum (2008)
Gibbs, Richard A, Weinstock, George M, Brown, Susan J, Denell, Robin, Beeman, Richard W, ...
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural...
Wolf, Jochen B. W., Harrod, Chris, Brunner, Sylvia, Salazar, Sandie, Trillmich, Fritz, Tautz, Diethard
Background: Oceans are high gene flow environments that are traditionally believed to hamper the build-up of genetic divergence. Despite this, divergence appears to occur occasionally at surprisingly...
Delimiting the conserved features of hunchback function for the trunk organization of insects (2008)
Marques-Souza, Henrique, Aranda, Manuel, Tautz, Diethard
The gap gene hunchback in Drosophila acts during syncytial blastoderm stage via a short-range gradient and concentration-dependent activation or repression of target genes. Orthologues of hunchback...
The role of the segmentation gene hairy in Tribolium (2008)
Aranda, Manuel, Marques-Souza, Henrique, Bayer, Till, Tautz, Diethard
Hairy stripes in Tribolium are generated during blastoderm and germ band extension, but a direct role for Tc-h in trunk segmentation was not found. We have studied here several aspects of hairy...
Pozhitkov, Alex E., Nies, Georg, Kleinhenz, Barbara, Tautz, Diethard, Noble, Peter A.
To date, it has been problematic to accurately quantify multiple nucleic acid sequences, representing microbial targets, in multi-target mixtures using oligonucleotide microarrays, primarily due to...
An ancient evolutionary origin of genes associated with human genetic diseases (2008)
Domazet-Lošo, Tomislav, Tautz, Diethard
Several thousand genes in the human genome have been linked to a heritable genetic disease. The majority of these appear to be non-essential genes (i.e. are not embryonically lethal when inactivated)...
Teschke, Meike, Mukabayire, Odette, Wiehe, Thomas, Tautz, Diethard
Genome scans of polymorphisms promise to provide insights into the patterns and frequencies of positive selection Under natural conditions. The use of microsatellites as markers has the potential to...
An ancient evolutionary origin of genes associated with human genetic diseases (2008)
Domazet-Lošo, Tomislav, Tautz, Diethard
Several thousand genes in the human genome have been linked to a heritable genetic disease. The majority of these appear to be nonessential genes (i.e., are not embryonically lethal when...
The genome of the model beetle and pest Tribolium castaneum (2008)
Gibbs, Richard A., Weinstock, George M., Brown, Susan J., Denell, Robin, Beeman, Richard W., ...
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural...
Delimiting the conserved features of hunchback function for the trunk organization of insects (2008)
Marques-Souza, Henrique, Aranda, Manuel, Tautz, Diethard
The gap gene hunchback in Drosophila acts during syncytial blastoderm stage via a short-range gradient and concentration-dependent activation or repression of target genes. Orthologues of hunchback...
An Ancient Evolutionary Origin of Genes Associated with Human Genetic Diseases (2008)
Domazet-Loso, Tomislav, Tautz, Diethard
Several thousand genes in the human genome have been linked to a heritable genetic disease. The majority of these appear to be nonessential genes (i.e., are not embryonically lethal when...
BMC Evolutionary Biology BioMed Central (2008)
Jochen Bw Wolf, Chris Harrod, Sylvia Brunner, Ie Salazar, Fritz Trillmich, Diethard Tautz
Research article Tracing early stages of species differentiation: Ecological, morphological and genetic divergence of Galápagos sea lion populations
oligo-nucleotide probes for species identification (2007)
Bmc Bioinformatics, Er E Pozhitkov, Diethard Tautz
An algorithm and program for finding sequence specific
Oligonucleotide microarrays: widely applied poorly understood (2007)
Pozhitkov, Alex E., Tautz, Diethard, Noble, Peter A.
Microarray technology, which has been around for almost two decades, now provides an indispensable service to the biomedical research community. Soaring demand for high-throughput screening of genes...
Wolf, Jochen BW, Tautz, Diethard, Trillmich, Fritz
Abstract Background Accurate formal taxonomic designations are thought to be of critical importance for the conservation of endangered taxa. The Galápagos sea lion (GSL), being appreciated as a key...
An evaluation of LSU rDNA D1-D2 sequences for their use in species identification (2007)
Sonnenberg, Rainer, Nolte, Arne W, Tautz, Diethard
Abstract Background Identification of species via DNA sequences is the basis for DNA taxonomy and DNA barcoding. Currently there is a strong focus on using a mitochondrial marker for this purpose, in...
Voolstra, Christian, Tautz, Diethard, Farbrother, Patrick, Eichinger, Ludwig, Harr, Bettina
Regulatory changes in genes involved in reproduction are thought to be prime targets for divergence during speciation, since they are expected to play an important role in sexual selection and sexual...
Genome-wide acceleration of protein evolution in flies (Diptera) (2006)
Savard, Joël, Tautz, Diethard, Lercher, Martin J
Abstract Background The rate of molecular evolution varies widely between proteins, both within and among lineages. To what extent is this variation influenced by genome-wide, lineage-specific...
Pozhitkov, Alex, Noble, Peter A., Domazet-Loso, Tomislav, Nolte, Arne W., Sonnenberg, Rainer, Staehler, Peer, ...
Hybridization of rRNAs to microarrays is a promising approach for prokaryotic and eukaryotic species identification. Typically, the amount of bound target is measured by fluorescent intensity and it...
Savard, Joël, Tautz, Diethard, Richards, Stephen, Weinstock, George M., Gibbs, Richard A., Werren, John H., ...
Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups...
An Analysis of Signatures of Selective Sweeps in Natural Populations of the House Mouse (2006)
Ihle, Sonja, Ravaoarimanana, Iary, Thomas, Meike, Tautz, Diethard
Population and locus-specific reduction of variability of polymorphic loci could be an indication of positive selection at a linked site (selective sweep) and therefore point toward genes that have...
Savard, Joël, Tautz, Diethard, Richards, Stephen, Weinstock, George M., Gibbs, Richard A., Werren, John H., ...
Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups...
Voolstra, Christian, Tautz, Diethard, Farbrother, Patrick, Eichinger, Ludwig, Harr, Bettina
Regulatory changes in genes involved in reproduction are thought to be prime targets for divergence during speciation, since they are expected to play an important role in sexual selection and sexual...
An Analysis of Signatures of Selective Sweeps in Natural Populations of the House Mouse (2006)
Ihle, Sonja, Ravaoarimanana, Iary, Thomas, Meike, Tautz, Diethard
Population and locus specific reduction of variability of polymorphic loci could be an indication of positive selection at a linked site (selective sweep) and therefore point towards genes that have...
Savard, Joël, Tautz, Diethard, Richards, Stephen, Weinstock, George M., Gibbs, Richard A., Werren, John H., ...
Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups...
Voolstra, Christian, Tautz, Diethard, Farbrother, Patrick, Eichinger, Ludwig, Harr, Bettina
Regulatory changes in genes involved in reproduction are thought to be prime targets for divergence during speciation, since they are expected to play an important role in sexual selection and sexual...
An Analysis of Signatures of Selective Sweeps in Natural Populations of the House Mouse (2006)
Ihle, Sonja, Ravaoarimanana, Iary, Thomas, Meike, Tautz, Diethard
Population and locus specific reduction of variability of polymorphic loci could be an indication of positive selection at a linked site (selective sweep) and therefore point towards genes that have...
Pozhitkov, Alexander, Stemshorn, Kathryn, Tautz, Diethard
Abstract Background Determination and quantification of nucleic acid components in a mixture is usually accomplished by microarray approaches, where the mixtures are hybridized against specific...
WHAT WE HAVE ALSO LEARNED: ADAPTIVE SPECIATION IS THEORETICALLY PLAUSIBLE (2005)
Michael Doebeli, Ulf Dieckmann, Diethard Tautz
A recent Perspectives article by Gavrilets (2003) on the theory of speciation ignored advances in understanding processes of adaptive speciation, in which the splitting of lineages is an adaptation...
Joël Savard, Diethard Tautz, Martin J Lercher, Open Access
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Introducing "Frontiers in Zoology" (2004)
Heinze, Jürgen, Tautz, Diethard
Abstract As a biological discipline, zoology has one of the longest histories. Today it occasionally appears as though, due to the rapid expansion of life sciences, zoology has been replaced by more...
Characterization of spotted hyena, Crocuta crocuta microsatellite loci (2003)
Wilhelm, Kerstin, Dawson, Deborah A., Gentle, Louise K., Horsfield, Giles F., Schlötterer, Christian, Greig, Carolyn, ...
An Evolutionary Analysis of Orphan Genes in Drosophila (2003)
Domazet-Loso, Tomislav, Tautz, Diethard
Orphan genes are protein-coding regions that have no recognizable homolog in distantly related species. A substantial fraction of coding regions in any genome sequenced consists of orphan genes, but...
DNA points the way ahead in taxonomy (2002)
Diethard Tautz, Peter Arctander, Alessandro Minelli, Richard H. Thomas, Alfried P. Vogler
Pozhitkov, Alexander E, Tautz, Diethard
Abstract Background The identification of species or species groups with specific oligo-nucleotides as molecular signatures is becoming increasingly popular for bacterial samples. However, it shows...
Molecular technologies for biodiversity evaluation: Opportunities and challenges (1997)
Angela Karp, Keith J. Edwards, Mike Bruford, Stephan Funk, Ben Vosman, Michele Morgante, ...
Friedrich, Markus, Tautz, Diethard
Portions of the large ribosomal subunit RNA gene (28S rDNA) encompassing the Dl and the D7 region were obtained from 16 dipteran species and families to reconstruct early phylogenetic events in the...
Slippage synthesis of simple sequence DNA (1992)
Schlötterer, Christian, Tautz, Diethard
The analysis of slippage synthesis of simple sequence DNA in vitro sheds some light on the question of how simple sequences arise in vivo. We show that it is possible to synthesize all types of...
Hypervariabflity of simple sequences as a general source for polymorphic DNA markers (1989)
Short simple sequence stretches occur as highly repetitive elements in all eukaryotic genomes and partially also in prokaryotes and eubacteria (1–6). They are thought to arise by slippage like...
Cross-regulatory interactions among the gap genes of Drosophila (1986)
Herbert Jäckle, Diethard Tautz, Reinhard Schuh, Eveline Seifert, Ruth Lehmann
Simple sequences are ubiquitous repetitive components of eukaryotic genomes (1984)
Tautz, Diethard, Renz, Manfred
Simple sequences are stretches of DNA which consist of only one, or a few tandemly repeated nucleotides, for example poly (dA).poly (dT) or poly (dG-dT).poly (dC-dA). These two types of simple...
Damen, Wim G. M., Weller, Mathias, Tautz, Diethard
There is an ongoing discussion on whether segmentation in different phyla has a common origin sharing a common genetic program. However, before comparing segmentation between phyla, it is necessary...
Conserved and divergent aspects of terminal patterning in the beetle Tribolium castaneum
Schröder, Reinhard, Eckert, Christoph, Wolff, Christian, Tautz, Diethard
To infer similarities and differences in terminal pattern formation in insects, we analyzed several of the key genes of this process in the beetle Tribolium castaneum. We cloned two genes of the...
Mitochondrial sequences show diverse evolutionary histories of African hominoids
Gagneux, Pascal, Wills, Christopher, Gerloff, Ulrike, Tautz, Diethard, Morin, Phillip A., Boesch, Christophe, ...
Phylogenetic trees for the four extant species of African hominoids are presented, based on mtDNA control region-1 sequences from 1,158 unique haplotypes. We include 83 new haplotypes of western...
A screen for fast evolving genes from Drosophila
Schmid, Karl J., Tautz, Diethard
In an attempt to quantify the rates of protein sequence divergence in Drosophila, we have devised a screen to differentiate between slow and fast evolving genes. We find that over one-third of...
Damen, Wim G. M., Hausdorf, Monika, Seyfarth, Ernst-August, Tautz, Diethard
Chelicerates constitute a basic arthropod group with fossil representatives from as early as the Cambrian period. Embryonic development and the subdivision of the segmented body region into a prosoma...
An Evolutionary Analysis of Orphan Genes in Drosophila
Domazet-Loso, Tomislav, Tautz, Diethard
Orphan genes are protein-coding regions that have no recognizable homolog in distantly related species. A substantial fraction of coding regions in any genome sequenced consists of orphan genes, but...
Introducing "Frontiers in Zoology"
Heinze, Jürgen, Tautz, Diethard
As a biological discipline, zoology has one of the longest histories. Today it occasionally appears as though, due to the rapid expansion of life sciences, zoology has been replaced by more or less...
Tautz, Diethard, Dover, Gabriel A.
Transcription termination of the polymerase I transcribed rRNA genes is thought to occur at or closely behind the end of the 28S gene coding region. We show here that this is not the case for...
Separable stripe enhancer elements for the pair-rule gene hairy in the beetle Tribolium
Eckert, Christoph, Aranda, Manuel, Wolff, Christian, Tautz, Diethard
Pair-rule genes in Drosophila integrate the positional information provided by the transcription factor gradients of gap genes and set the framework for the expression of the segment polarity genes....
Pozhitkov, Alex, Noble, Peter A., Domazet-Lošo, Tomislav, Nolte, Arne W., Sonnenberg, Rainer, Staehler, Peer, ...
Hybridization of rRNAs to microarrays is a promising approach for prokaryotic and eukaryotic species identification. Typically, the amount of bound target is measured by fluorescent intensity and it...
Damen, Wim G. M., Weller, Mathias, Tautz, Diethard
There is an ongoing discussion on whether segmentation in different phyla has a common origin sharing a common genetic program. However, before comparing segmentation between phyla, it is necessary...
Conserved and divergent aspects of terminal patterning in the beetle Tribolium castaneum
Schröder, Reinhard, Eckert, Christoph, Wolff, Christian, Tautz, Diethard
To infer similarities and differences in terminal pattern formation in insects, we analyzed several of the key genes of this process in the beetle Tribolium castaneum. We cloned two genes of the...
Mitochondrial sequences show diverse evolutionary histories of African hominoids
Gagneux, Pascal, Wills, Christopher, Gerloff, Ulrike, Tautz, Diethard, Morin, Phillip A., Boesch, Christophe, ...
Phylogenetic trees for the four extant species of African hominoids are presented, based on mtDNA control region-1 sequences from 1,158 unique haplotypes. We include 83 new haplotypes of western...
A screen for fast evolving genes from Drosophila
Schmid, Karl J., Tautz, Diethard
In an attempt to quantify the rates of protein sequence divergence in Drosophila, we have devised a screen to differentiate between slow and fast evolving genes. We find that over one-third of...
Damen, Wim G. M., Hausdorf, Monika, Seyfarth, Ernst-August, Tautz, Diethard
Chelicerates constitute a basic arthropod group with fossil representatives from as early as the Cambrian period. Embryonic development and the subdivision of the segmented body region into a prosoma...
An Evolutionary Analysis of Orphan Genes in Drosophila
Domazet-Loso, Tomislav, Tautz, Diethard
Orphan genes are protein-coding regions that have no recognizable homolog in distantly related species. A substantial fraction of coding regions in any genome sequenced consists of orphan genes, but...
Introducing "Frontiers in Zoology"
Heinze, Jürgen, Tautz, Diethard
As a biological discipline, zoology has one of the longest histories. Today it occasionally appears as though, due to the rapid expansion of life sciences, zoology has been replaced by more or less...
Tautz, Diethard, Dover, Gabriel A.
Transcription termination of the polymerase I transcribed rRNA genes is thought to occur at or closely behind the end of the 28S gene coding region. We show here that this is not the case for...
Separable stripe enhancer elements for the pair-rule gene hairy in the beetle Tribolium
Eckert, Christoph, Aranda, Manuel, Wolff, Christian, Tautz, Diethard
Pair-rule genes in Drosophila integrate the positional information provided by the transcription factor gradients of gap genes and set the framework for the expression of the segment polarity genes....
Pozhitkov, Alex, Noble, Peter A., Domazet-Lošo, Tomislav, Nolte, Arne W., Sonnenberg, Rainer, Staehler, Peer, ...
Hybridization of rRNAs to microarrays is a promising approach for prokaryotic and eukaryotic species identification. Typically, the amount of bound target is measured by fluorescent intensity and it...
The hidden matrilineal structure of a solitary lemur: implications for primate social evolution.
Kappeler, Peter M, Wimmer, Barbara, Zinner, Dietmar, Tautz, Diethard
Kin selection affects many aspects of social behaviour, especially in gregarious animals in which relatives are permanently associated. In most group-living primates with complex social behaviour,...
Savard, Joël, Tautz, Diethard, Richards, Stephen, Weinstock, George M., Gibbs, Richard A., Werren, John H., ...
Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups...
Voolstra, Christian, Tautz, Diethard, Farbrother, Patrick, Eichinger, Ludwig, Harr, Bettina
Regulatory changes in genes involved in reproduction are thought to be prime targets for divergence during speciation, since they are expected to play an important role in sexual selection and sexual...
Nolte, Arne W, Freyhof, Jörg, Stemshorn, Kathryn C, Tautz, Diethard
Fish abundance surveys in the Rhine system have shown in the past two decades that there is a rapid upriver invasion of a freshwater sculpin of the genus Cottus. These fish are found in habitats that...
Markmann, Melanie, Tautz, Diethard
Organisms living in or on the sediment layer of water bodies constitute the benthos fauna, which is known to harbour a large number of species of diverse taxonomic groups. The benthos plays a...
The role of the segmentation gene hairy in Tribolium
Aranda, Manuel, Marques-Souza, Henrique, Bayer, Till, Tautz, Diethard
Hairy stripes in Tribolium are generated during blastoderm and germ band extension, but a direct role for Tc-h in trunk segmentation was not found. We have studied here several aspects of hairy...
An Ancient Evolutionary Origin of Genes Associated with Human Genetic Diseases
Domazet-Lošo, Tomislav, Tautz, Diethard
Several thousand genes in the human genome have been linked to a heritable genetic disease. The majority of these appear to be nonessential genes (i.e., are not embryonically lethal when...
Teschke, Meike, Mukabayire, Odette, Wiehe, Thomas, Tautz, Diethard
Genome scans of polymorphisms promise to provide insights into the patterns and frequencies of positive selection under natural conditions. The use of microsatellites as markers has the potential to...
Johnsen, Jill M., Teschke, Meike, Pavlidis, Pavlos, McGee, Beth M., Tautz, Diethard, Ginsburg, David, ...
The RIIIS/J inbred mouse strain is a model for type 1 von Willebrand disease (VWD), a common human bleeding disorder. Low von Willebrand factor (VWF) levels in RIIIS/J are due to a regulatory...