Synapsin- and Actin-Dependent Frequency Enhancement in Mouse Hippocampal Mossy Fiber Synapses (2009)
Owe, Simen G., Jensen, Vidar, Evergren, Emma, Ruiz, Arnaud, Shupliakov, Oleg, Kullmann, Dimitri M., ...
The synapsin proteins have different roles in excitatory and inhibitory synaptic terminals. We demonstrate a differential role between types of excitatory terminals. Structural and functional aspects...
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia (2004)
Imbrici, Paola, Jaffe, Stephen L., Eunson, Louise H., Davies, Nicholas P., Herd, Colin, Robertson, Robert, ...
Summary The molecular basis of idiopathic generalized epilepsy remains poorly understood. Absence epilepsy with 3 Hz spike-wave EEG is one of the most common human epilepsies, and is associated with...
Rusakov, Dmitri A., Wuerz, Axel, Kullmann, Dimitri M.
GABA release from axonal boutons formed by cortical interneurons shows target cell-dependent sensitivity to group III metabotropic glutamate receptor (mGluR) agonists, as well as variable dependence...
Rusakov, Dmitri A., Wuerz, Axel, Kullmann, Dimitri M.
GABA release from axonal boutons formed by cortical interneurons shows target cell-dependent sensitivity to group III metabotropic glutamate receptor (mGluR) agonists, as well as variable dependence...
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia (2004)
Imbrici, Paola, Jaffe, Stephen L., Eunson, Louise H., Davies, Nicholas P., Herd, Colin, Robertson, Robert, ...
The molecular basis of idiopathic generalized epilepsy remains poorly understood. Absence epilepsy with 3 Hz spike–wave EEG is one of the most common human epilepsies, and is associated with...
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia (2004)
Imbrici, Paola, Jaffe, Stephen L., Eunson, Louise H., Davies, Nicholas P., Herd, Colin, Robertson, Robert, ...
Summary The molecular basis of idiopathic generalized epilepsy remains poorly understood. Absence epilepsy with 3 Hz spike-wave EEG is one of the most common human epilepsies, and is associated with...
Rusakov, Dmitri A., Wuerz, Axel, Kullmann, Dimitri M.
GABA release from axonal boutons formed by cortical interneurons shows target cell-dependent sensitivity to group III metabotropic glutamate receptor (mGluR) agonists, as well as variable dependence...
The neuronal channelopathies (2002)
This review addresses the molecular and cellular mechanisms of diseases caused by inherited mutations of ion channels in neurones. Among important recent advances is the elucidation of several...
Geometric and viscous components of the tortuosity of the extracellular space in the brain
Rusakov, Dmitri A., Kullmann, Dimitri M.
To understand the function of neuro-active molecules, it is necessary to know how far they can diffuse in the brain. Experimental measurements show that substances confined to the extracellular space...
Min, Ming-Yuan, Melyan, Zare, Kullmann, Dimitri M.
Exogenous application of agonists at the kainate subtype of glutamate receptors has been shown to depress evoked monosynaptic inhibition by γ-aminobutyric acid (GABA)ergic interneurons in the...
Long-term potentiation and dual-component quantal signaling in the dentate gyrus
Min, Ming-Yuan, Asztely, Fredrik, Kokaia, Merab, Kullmann, Dimitri M.
Long-term potentiation (LTP) of excitatory transmission is an important candidate cellular mechanism for the storage of memories in the mammalian brain. The subcellular phenomena that underlie the...
Complementary roles of intra- and extra-synaptic NMDA receptors in homeostatic synaptic plasticity?
Rusakov, Dmitri A, Scimemi, Annalisa, Walker, Matthew C, Kullmann, Dimitri M
Liu et al (Science, 304:1021-4) report that NMDA receptors containing NR2A and NR2B subunits are selectively coupled to long-term potentiation (LTP) and long-term depression (LTD) respectively....
Geometric and viscous components of the tortuosity of the extracellular space in the brain
Rusakov, Dmitri A., Kullmann, Dimitri M.
To understand the function of neuro-active molecules, it is necessary to know how far they can diffuse in the brain. Experimental measurements show that substances confined to the extracellular space...
Min, Ming-Yuan, Melyan, Zare, Kullmann, Dimitri M.
Exogenous application of agonists at the kainate subtype of glutamate receptors has been shown to depress evoked monosynaptic inhibition by γ-aminobutyric acid (GABA)ergic interneurons in the...
Long-term potentiation and dual-component quantal signaling in the dentate gyrus
Min, Ming-Yuan, Asztely, Fredrik, Kokaia, Merab, Kullmann, Dimitri M.
Long-term potentiation (LTP) of excitatory transmission is an important candidate cellular mechanism for the storage of memories in the mammalian brain. The subcellular phenomena that underlie the...
Silent synapses: what are they telling us about long-term potentiation?
At several cortical synapses glutamate release events can be mediated exclusively by NMDA receptors, with no detectable contribution from AMPA receptors. This observation was originally made by...
Variable K+ channel subunit dysfunction in inherited mutations of KCNA1
Rea, Ruth, Spauschus, Alexander, Eunson, Louise H, Hanna, Michael G, Kullmann, Dimitri M
Mutations of KCNA1, which codes for the K+ channel subunit hKv1.1, are associated with the human autosomal dominant disease episodic ataxia type 1 (EA1). Five recently described mutations are...
Lamsa, Karri, Irvine, Elaine E, Giese, K Peter, Kullmann, Dimitri M
Long-term potentiation (LTP) of excitatory synaptic transmission plays a major role in memory encoding in the cerebral cortex. It can be elicited at many synapses on principal cells, where it depends...
Synapsin- and Actin-Dependent Frequency Enhancement in Mouse Hippocampal Mossy Fiber Synapses
Owe, Simen G., Jensen, Vidar, Evergren, Emma, Ruiz, Arnaud, Shupliakov, Oleg, Kullmann, Dimitri M., ...
The synapsin proteins have different roles in excitatory and inhibitory synaptic terminals. We demonstrate a differential role between types of excitatory terminals. Structural and functional aspects...
Roles of distinct glutamate receptors in induction of anti-Hebbian long-term potentiation
Kullmann, Dimitri M, Lamsa, Karri
Many glutamatergic synapses on interneurons involved in feedback inhibition in the CA1 region of the hippocampus exhibit an unusual form of long-term potentiation (LTP) that is induced only if...