Dinesh Gupta

A systematic classification of Plasmodium falciparumP-loop NTPases: structural and functional correlation (2009)

Gangwar, Deepti, Kalita, Mridul K, Gupta, Dinesh, Chauhan, Virander S, Mohmmed, Asif

Abstract Background The P-loop NTPases constitute one of the largest groups of globular protein domains that play highly diverse functional roles in most of the organisms. Even with the availability...

ProtVirDB: a database of protozoan virulent proteins (2009)

Ramana, Jayashree, Gupta, Dinesh

Summary: ProtVirDB is a comprehensive and user-friendly web-based knowledgebase of virulent proteins belonging to protozoan species. The database will facilitate research and provide an integrated...

VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens (2008)

Garg, Aarti, Gupta, Dinesh

Abstract Background Prediction of bacterial virulent protein sequences has implications for identification and characterization of novel virulence-associated factors, finding novel drug/vaccine...

Virtual high throughput screening (vHTS) - A perspective (2008)

Sangeetha Subramaniam, Monica Mehrotra, Dinesh Gupta

With the exponential rise in the number of viable novel drug targets, computational methods are being increasingly applied to accelerate the drug discovery process. Virtual High Throughput Screening...

ProtRepeatsDB: a database of amino acid repeats in genomes (2006)

Kalita, Mridul K, Ramasamy, Gowthaman, Duraisamy, Sekhar, Chauhan, Virander S, Gupta, Dinesh

Abstract Background Genome wide and cross species comparisons of amino acid repeats is an intriguing problem in biology mainly due to the highly polymorphic nature and diverse functions of amino acid...

A database for Plasmodium falciparum protein models (2005)

Ramasamy Gowthaman, Duraisamy Sekhar, Mridul Kumar Kalita, Dinesh Gupta

There is an urgent need for developing alternate strategies to combat Malaria caused by Plasmodium falciparum (P. falciparum) because of growing drug resistance and increased incidents of infection...

Distribution of proline-rich (PxxP) motifs in distinct proteomes: functional and therapeutic implications for malaria and tuberculosis (2004)

Ravi Chandra, Beeram, Gowthaman, Ramasamy, Raj Akhouri, Reetesh, Gupta, Dinesh, Sharma, Amit

We have conducted a survey of proline‐rich (PxxP) motifs in the proteomes of human, mouse, yeast, Mycobacterium tuberculosis and Plasmodium falciparum. Our analyses reveal a strikingly high...

Distribution of proline-rich (PxxP) motifs in distinct proteomes: functional and therapeutic implications for malaria and tuberculosis (2004)

Chandra, Beeram Ravi, Gowthaman, Ramasamy, Akhouri, Reetesh Raj, Gupta, Dinesh, Sharma, Amit

We have conducted a survey of proline-rich (PxxP) motifs in the proteomes of human, mouse, yeast, Mycobacterium tuberculosis and Plasmodium falciparum. Our analyses reveal a strikingly high...

Distribution of proline-rich (PxxP) motifs in distinct proteomes: functional and therapeutic implications for malaria and tuberculosis (2004)

Chandra, Beeram Ravi, Gowthaman, Ramasamy, Akhouri, Reetesh Raj, Gupta, Dinesh, Sharma, Amit

We have conducted a survey of proline-rich (PxxP) motifs in the proteomes of human, mouse, yeast, Mycobacterium tuberculosis and Plasmodium falciparum. Our analyses reveal a strikingly high...

PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data (2003)

Bahl, Amit, Brunk, Brian, Crabtree, Jonathan, Fraunholz, Martin J., Gajria, Bindu, Grant, Gregory R., ...

PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently completed P. falciparum genome sequence and...

PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished) (2002)

Bahl, Amit, Brunk, Brian, Coppel, Ross L., Crabtree, Jonathan, Diskin, Sharon J., Fraunholz, Martin J., ...

PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates finished and draft genome sequence data and...

PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished)

Bahl, Amit, Brunk, Brian, Coppel, Ross L., Crabtree, Jonathan, Diskin, Sharon J., Fraunholz, Martin J., ...

PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates finished and draft genome sequence data and annotation...

PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data

Bahl, Amit, Brunk, Brian, Crabtree, Jonathan, Fraunholz, Martin J., Gajria, Bindu, Grant, Gregory R., ...

PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently completed P. falciparum genome sequence and...

PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished)

Bahl, Amit, Brunk, Brian, Coppel, Ross L., Crabtree, Jonathan, Diskin, Sharon J., Fraunholz, Martin J., ...

PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates finished and draft genome sequence data and annotation...

PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data

Bahl, Amit, Brunk, Brian, Crabtree, Jonathan, Fraunholz, Martin J., Gajria, Bindu, Grant, Gregory R., ...

PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently completed P. falciparum genome sequence and...

A database for Plasmodium falciparum protein models

Gowthaman, Ramasamy, Sekhar, Duraisamy, Kalita, Mridul Kumar, Gupta, Dinesh

There is an urgent need for developing alternate strategies to combat Malaria caused by Plasmodium falciparum (P. falciparum) because of growing drug resistance and increased incidents of infection...

CyclinPred: A SVM-Based Method for Predicting Cyclin Protein Sequences

Kalita, Mridul K., Nandal, Umesh K., Pattnaik, Ansuman, Sivalingam, Anandhan, Ramasamy, Gowthaman, Kumar, Manish, ...

Functional annotation of protein sequences with low similarity to well characterized protein sequences is a major challenge of computational biology in the post genomic era. The cyclin protein family...

Virtual high throughput screening (vHTS) - A perspective

Subramaniam, Sangeetha, Mehrotra, Monica, Gupta, Dinesh

With the exponential rise in the number of viable novel drug targets, computational methods are being increasingly applied to accelerate the drug discovery process. Virtual High Throughput Screening...