Djamel Lebeche

In vivo gene transfer of parvalbumin improves diastolic function in aged rat hearts (2005)

Schmidt, Ulrich, Zhu, Xinsheng, Lebeche, Djamel, Huq, Fawzia, Guerrero, J. Luis, Hajjar, Roger J.

Objective: Diastolic dysfunction is a characteristic finding of the aged mammalian heart. Parvalbumin acts as a Ca2+ sink and enhances relaxation in skeletal muscle, and overexpression of parvalbumin...

Chronic treatment with Carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure (2003)

Okafor, Chukwuka C, Perreault-Micale, Cynthia, Hajjar, Roger J, Lebeche, Djamel, Skiroman, Klara, Jabbour, George, ...

Abstract Background β-blocker treatment has emerged as an effective treatment modality for heart failure. Interestingly, β-blockers can activate both pro-apoptotic and anti-apoptotic pathways....

Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling

Del Monte, Federica, Lebeche, Djamel, Guerrero, J. Luis, Tsuji, Tsuyoshi, Doye, Angelia A., Gwathmey, Judith K., ...

Abnormal intracellular Ca2+ cycling plays an important role in cardiac dysfunction and ventricular arrhythmias in the setting of heart failure and transient cardiac ischemia followed by reperfusion...

Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling

Del Monte, Federica, Lebeche, Djamel, Guerrero, J. Luis, Tsuji, Tsuyoshi, Doye, Angelia A., Gwathmey, Judith K., ...

Abnormal intracellular Ca2+ cycling plays an important role in cardiac dysfunction and ventricular arrhythmias in the setting of heart failure and transient cardiac ischemia followed by reperfusion...