Dmitry M. Korzhnev

NMR detection of multiple transitions to low-populated states in azurin (2003)

Korzhnev, Dmitry M., Karlsson, B. Göran, Orekhov, Vladislav Yu., Billeter, Martin

Transitions to conformational states with very low populations were detected for the reduced blue copper protein azurin from Pseudomonas aeruginosa by applying constant relaxation time CPMG...

Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation

Di Nardo, Ariel A., Korzhnev, Dmitry M., Stogios, Peter J., Zarrine-Afsar, Arash, Kay, Lewis E., Davidson, Alan R.

Through a mutagenic investigation of Gly-48, a highly conserved position in the Src homology 3 domain, we have discovered a series of amino acid substitutions that are highly destabilizing, yet...

Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation

Di Nardo, Ariel A., Korzhnev, Dmitry M., Stogios, Peter J., Zarrine-Afsar, Arash, Kay, Lewis E., Davidson, Alan R.

Through a mutagenic investigation of Gly-48, a highly conserved position in the Src homology 3 domain, we have discovered a series of amino acid substitutions that are highly destabilizing, yet...

Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain

Murphy, James M., Korzhnev, Dmitry M., Ceccarelli, Derek F., Briant, Douglas J., Zarrine-Afsar, Arash, Sicheri, Frank, ...

The Par-1/MARK protein kinases play a pivotal role in establishing cellular polarity. This family of kinases contains a unique domain architecture, in which a ubiquitin-associated (UBA) domain is...

NMR detection of multiple transitions to low-populated states in azurin

Korzhnev, Dmitry M., Karlsson, B. Göran, Orekhov, Vladislav Yu., Billeter, Martin

Transitions to conformational states with very low populations were detected for the reduced blue copper protein azurin from Pseudomonas aeruginosa by applying constant relaxation time CPMG...