Donald H. Atha

Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopy (2007)

Reipa, Vytas, Niaura, Gediminas, Atha, Donald H.

We have measured the temperature-dependent Raman spectra of two 30-mer ribonucleotides that represent the wild-type (WT) and dyskeratosis congenita (DKC) mutant (MT) GC (107–108) → AG structures...

Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopy (2006)

Reipa, Vytas, Niaura, Gediminas, Atha, Donald H.

We have measured the temperature-dependent Raman spectra of two 30-mer ribonucleotides that represent the wild-type (WT) and dyskeratosis congenita (DKC) mutant (MT) GC (107–108) → AG...

Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopy (2006)

Reipa, Vytas, Niaura, Gediminas, Atha, Donald H.

We have measured the temperature-dependent Raman spectra of two 30-mer ribonucleotides that represent the wild-type (WT) and dyskeratosis congenita (DKC) mutant (MT) GC (107–108) → AG...

Prediction of DNA single-strand conformation polymorphism: analysis by capillary electrophoresis and computerized DNA modeling (2001)

Atha, Donald H., Kasprzak, Wojciech, O’Connell, Catherine D., Shapiro, Bruce A.

We have analyzed previously three representative p53 single-point mutations by capillary-electrophoresis single-strand conformation polymorphism (CE-SSCP). In the current study, we compared our...

Prediction of DNA single-strand conformation polymorphism: analysis by capillary electrophoresis and computerized DNA modeling

Atha, Donald H., Kasprzak, Wojciech, O’Connell, Catherine D., Shapiro, Bruce A.

We have analyzed previously three representative p53 single-point mutations by capillary-electrophoresis single-strand conformation polymorphism (CE-SSCP). In the current study, we compared our...

Prediction of DNA single-strand conformation polymorphism: analysis by capillary electrophoresis and computerized DNA modeling

Atha, Donald H., Kasprzak, Wojciech, O’Connell, Catherine D., Shapiro, Bruce A.

We have analyzed previously three representative p53 single-point mutations by capillary-electrophoresis single-strand conformation polymorphism (CE-SSCP). In the current study, we compared our...

Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopy

Reipa, Vytas, Niaura, Gediminas, Atha, Donald H.

We have measured the temperature-dependent Raman spectra of two 30-mer ribonucleotides that represent the wild-type (WT) and dyskeratosis congenita (DKC) mutant (MT) GC (107–108) → AG structures...

Analytical Validation of Telomerase Activity for Cancer Early Detection : TRAP/PCR-CE and hTERT mRNA Quantification Assay for High-Throughput Screening of Tumor Cells

Jakupciak, John P., Wang, Wendy, Barker, Peter E., Srivastava, Sudhir, Atha, Donald H.

Activation of telomerase plays a critical role in unlimited proliferation and immortalization of cells. Telomerase activity has been shown to correlate with tumor progression, indicating that tumors...