Femtosecond molecular dynamics of complex reactions (2008)
The exploring of complex reactions within femtosecond resolution provides new challenges because the reactions evolve along multiple pathways. New techniques are needed to dissect these complex...
MAPPING HYDRATION DYNAMICS AND COUPLED WATER-PROTEIN FLUCTUATIONS AROUND A PROTEIN SURFACE (2008)
Zhang, Luyuan, Wang, Lijuan, Kao, Ya-Ting, Qiu, Weihong, Yang, Yi, Okobiah, Oghaghare, ...
Author Institution: Departments of Physics, Chemistry, and Biochemistry, Programs of Biophysics, Chemical Physics, and Biochemistry, 191 West Woodruff Avenue, The Ohio State University, Columbus, OH...
ULTRAFAST SHORT-RANGE ELECTRON TRANSFER DYNAMICS IN BIOLOGY (2008)
He, Ting-Fang, Guo, Lijun, Zhong, Dongping
Author Institution: Programs of Ohio State Biochemistry, Biophysics, and Chemical Physics, and Departments of Physics, Chemistry, and Biochemistry, The Ohio State University, Columbus, OH 43210
Kao, Ya-Ting, Tan, Chuang, Li, Jiang, Wang, Lijuan, Zhong, Dongping
Author Institution: Chemistry, and Biochemistry, Programs of Biophysics, Chemical Physics, and Biochemistry, The Ohio State University, Columbus, Ohio, 43210
Zang, Chen, Stevens, Jeffrey A., Link, Justin J., Guo, Lijun, Zhong, Dongping
Author Institution: Department of Physics, The Ohio State University, Columbus, Ohio, 43210
Protein surface hydration mapped by site-specific mutations (2006)
Qiu, Weihong, Kao, Ya-Ting, Zhang, Luyuan, Yang, Yi, Wang, Lijuan, Stites, Wesley E., ...
Water motion at protein surfaces is fundamental to protein structure, stability, dynamics, and function. By using intrinsic tryptophans as local optical probes, and with femtosecond resolution, it is...
Qiu, Weihong, Zhang, Luyuan, Okobiah, Oghaghare, Yang, Yi, Wang, Lijuan, Zhong, Dongping, ...
Author Institution: Departments of Physics, Chemistry, and Biochemistry, Programs of Biophysics, Chemical Physics, and Biochemistry, The Ohio State University, Columbus, OH 43210; Laboratory of...
ULTRAFAST DYNAMICS OF RESONANCE ENERGY TRANSFER IN MYOGLOBIN (2006)
Link, Justin J., Stevens, Jeffrey A., Kao, Ya-Ting, Zhong, Dongping
Author Institution: Department of Physics, The Ohio State University, Columbus, OH 43210
Hassanali, Ali A., Li, Tanping, Zhong, Dongping, Singer, Sherwin J.
Author Institution: Biophysics Program, Department of Physics and Department; of Chemistry, The Ohio State University, Columbus, OH 43210
ULTRAFAST HYDRATION DYNAMICS OF MELITTIN: HELIX FORMATION AND TETRAMER SELF-ASSEMBLY (2005)
Zhang, Luyuan, Qiu, Weihong, Zhong, Dongping
Author Institution: Departments of Physics, Chemistry, and Biochemistry, OSU Chemical Physics and Biophysics Programs, The Ohio State University, Columbus, OH 43210
DIRECT OBSERVATION OF DNA REPAIR IN PHOTOLYASE (2005)
Kao, Ya-Ting, Saxena, Chaitanya, Wang, Lijuan, Zhong, Dongping
Author Institution: Department of Physics, Chemistry and Biochemistry, OSU Biophysics, Chemical Physics and Biochemistry Programs, The Ohio State University, Columbus, Ohio 43210
FEMTOSECOND HYDRATION DYNAMICS OF APOMYOGLOBIN: NATIVE AND MOLTEN GLOBULE STATES (2004)
Kim, Jongjoo, Qiu, Weihong, Lu, Wenyun, Zhong, Dongping
Author Institution: Department of Physics, The Ohio-State University
FEMTOSECOND STUDIES OF HUMAN THIOREDOXIN: DISSECTION OF COMPLEX DYNAMICS IN PROTEIN (2004)
Qiu, Weihong, Zhong, Dongping, Lu, Wenyun
Author Institution: OSU Biophysics Program, The Ohio-State University; Department of Physics, The Ohio-State University
FEMTOSECOND DYNAMICS OF RESONANCE ENERGY AND ELECTRON TRANSFER IN DNA-PHOTOLYASE ENZYME (2004)
Saxena, Chaitanya, Zhong, Dongping
Author Institution: OSU Biophysics Program, The Ohio-State University
FEMTOSECOND CORRELATION SPECTROSCOPY (2003)
Zhong, Dongping, Zewail, Ahmed H.
Author Institution: Departments of Physics, Chemistry and Biochemistry, The Ohio State University; Laboratory for Molecular Sciences, Arthur Amos Noyes Laboratory of Chemical Physics, California...
Zhong, Dongping, Pal, Sumir Kumar, Zhang, Deqiang, Chan, Sunney I., Zewail, Ahmed H.
We report here studies of tryptophan (Trp) solvation dynamics in water and in the Pyrococcus furiosus rubredoxin protein, including the native and its apo and denatured forms. We also report results...
Qu, Xiaogang, Wan, Chaozhi, Becker, Hans-Christian, Zhong, Dongping, Zewail, Ahmed H.
The anthracycline-DNA complex, which is a potent agent for cancer chemotherapy, has a unique intercalating molecular structure with preference to the GC bases of DNA, as shown by Rich's group in...
Zhong, Dongping, Pal, Samir Kumar, Wan, Chaozhi, Zewail, Ahmed H.
In this contribution, we report studies of the primary dynamics of the drug-protein complexes of daunomycin with apo riboflavin-binding protein. With femtosecond resolution, we observed the ultrafast...
Zhong, Dongping, Zewail, Ahmed H.
Flavoproteins can function as hydrophobic sites for vitamin B2 (riboflavin) or, in other structures, with cofactors for catalytic reactions such as glucose oxidation. In this contribution, we report...
Femtosecond studies of protein-ligand hydrophobic binding and dynamics: Human serum albumin (2000)
Zhong, Dongping, Douhal, Abderrazzak, Zewail, Ahmed H.
In this contribution, we report studies of the nature of the dynamics and hydrophobic binding in protein-ligand complexes of human serum albumin with 2-(2'-hydroxyphenyl)-4-methyloxazole. With...
Femtosecond molecular dynamics of complex reactions (1999)
The exploring of complex reactions within femtosecond resolution provides new challenges because the reactions evolve along multiple pathways. New techniques are needed to dissect these complex...
Zhong, Dongping, Zewail, Ahmed H.
With fs time, speed, and angular resolution of the elementary steps in electron transfer reactions, we report direct observation of reversible and dissociative processes for dative bonding involving...
Reactions of metastable Rg(³P₀, ³P₂) atoms (Rg=Kr, Xe) with halogen-containing molecules / (1995)
Thesis (M.S.)--Kansas State University, 1995.
Zhong, Dongping, Zewail, Ahmed H.
With fs time, speed, and angular resolution of the elementary steps in electron transfer reactions, we report direct observation of reversible and dissociative processes for dative bonding involving...
Femtosecond studies of protein–ligand hydrophobic binding and dynamics: Human serum albumin
Zhong, Dongping, Douhal, Abderrazzak, Zewail, Ahmed H.
In this contribution, we report studies of the nature of the dynamics and hydrophobic binding in protein–ligand complexes of human serum albumin with 2-(2′-hydroxyphenyl)-4-methyloxazole. With...
Zhong, Dongping, Zewail, Ahmed H.
Flavoproteins can function as hydrophobic sites for vitamin B2 (riboflavin) or, in other structures, with cofactors for catalytic reactions such as glucose oxidation. In this contribution, we report...
Femtosecond dynamics of a drug–protein complex: Daunomycin with Apo riboflavin-binding protein
Zhong, Dongping, Pal, Samir Kumar, Wan, Chaozhi, Zewail, Ahmed H.
In this contribution, we report studies of the primary dynamics of the drug–protein complexes of daunomycin with apo riboflavin-binding protein. With femtosecond resolution, we observed the...
The anticancer drug–DNA complex: Femtosecond primary dynamics for anthracycline antibiotics function
Qu, Xiaogang, Wan, Chaozhi, Becker, Hans-Christian, Zhong, Dongping, Zewail, Ahmed H.
The anthracycline–DNA complex, which is a potent agent for cancer chemotherapy, has a unique intercalating molecular structure with preference to the GC bases of DNA, as shown by Rich's group in...
Zhong, Dongping, Pal, Samir Kumar, Zhang, Deqiang, Chan, Sunney I., Zewail, Ahmed H.
We report here studies of tryptophan (Trp) solvation dynamics in water and in the Pyrococcus furiosus rubredoxin protein, including the native and its apo and denatured forms. We also report results...
Direct observation of thymine dimer repair in DNA by photolyase
Kao, Ya-Ting, Saxena, Chaitanya, Wang, Lijuan, Sancar, Aziz, Zhong, Dongping
Photolyase uses light energy to split UV-induced cyclobutane dimers in damaged DNA, but its molecular mechanism has never been directly revealed. Here, we report the direct mapping of catalytic...
Zhong, Dongping, Zewail, Ahmed H.
With fs time, speed, and angular resolution of the elementary steps in electron transfer reactions, we report direct observation of reversible and dissociative processes for dative bonding involving...
Femtosecond studies of protein–ligand hydrophobic binding and dynamics: Human serum albumin
Zhong, Dongping, Douhal, Abderrazzak, Zewail, Ahmed H.
In this contribution, we report studies of the nature of the dynamics and hydrophobic binding in protein–ligand complexes of human serum albumin with 2-(2′-hydroxyphenyl)-4-methyloxazole. With...
Zhong, Dongping, Zewail, Ahmed H.
Flavoproteins can function as hydrophobic sites for vitamin B2 (riboflavin) or, in other structures, with cofactors for catalytic reactions such as glucose oxidation. In this contribution, we report...
Femtosecond dynamics of a drug–protein complex: Daunomycin with Apo riboflavin-binding protein
Zhong, Dongping, Pal, Samir Kumar, Wan, Chaozhi, Zewail, Ahmed H.
In this contribution, we report studies of the primary dynamics of the drug–protein complexes of daunomycin with apo riboflavin-binding protein. With femtosecond resolution, we observed the...
The anticancer drug–DNA complex: Femtosecond primary dynamics for anthracycline antibiotics function
Qu, Xiaogang, Wan, Chaozhi, Becker, Hans-Christian, Zhong, Dongping, Zewail, Ahmed H.
The anthracycline–DNA complex, which is a potent agent for cancer chemotherapy, has a unique intercalating molecular structure with preference to the GC bases of DNA, as shown by Rich's group in...
Zhong, Dongping, Pal, Samir Kumar, Zhang, Deqiang, Chan, Sunney I., Zewail, Ahmed H.
We report here studies of tryptophan (Trp) solvation dynamics in water and in the Pyrococcus furiosus rubredoxin protein, including the native and its apo and denatured forms. We also report results...
Direct observation of thymine dimer repair in DNA by photolyase
Kao, Ya-Ting, Saxena, Chaitanya, Wang, Lijuan, Sancar, Aziz, Zhong, Dongping
Photolyase uses light energy to split UV-induced cyclobutane dimers in damaged DNA, but its molecular mechanism has never been directly revealed. Here, we report the direct mapping of catalytic...
Protein surface hydration mapped by site-specific mutations
Qiu, Weihong, Kao, Ya-Ting, Zhang, Luyuan, Yang, Yi, Wang, Lijuan, Stites, Wesley E., ...
Water motion at protein surfaces is fundamental to protein structure, stability, dynamics, and function. By using intrinsic tryptophans as local optical probes, and with femtosecond resolution, it is...
Dissection of complex protein dynamics in human thioredoxin
Qiu, Weihong, Wang, Lijuan, Lu, Wenyun, Boechler, Amanda, Sanders, David A. R., Zhong, Dongping
We report our direct study of complex protein dynamics in human thioredoxin by dissecting into elementary processes and determining their relevant time scales. By combining site-directed mutagenesis...
Mapping hydration dynamics around a protein surface
Zhang, Luyuan, Wang, Lijuan, Kao, Ya-Ting, Qiu, Weihong, Yang, Yi, Okobiah, Oghaghare, ...
Protein surface hydration is fundamental to its structure and activity. We report here the direct mapping of global hydration dynamics around a protein in its native and molten globular states, using...