Donna Walther

Publication List Details

Period

2005 - 2008

Number

13

Co-Authors

Genome wide association for substance dependence: convergent results from epidemiologic and research volunteer samples (2008)

Johnson, Catherine, Drgon, Tomas, Liu, Qing-Rong, Zhang, Ping-Wu, Walther, Donna, Li, Chuan-Yun, ...

Abstract Background Dependences on addictive substances are substantially-heritable complex disorders whose molecular genetic bases have been partially elucidated by studies that have largely focused...

Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms (2007)

Hishimoto, Akitoyo, Liu, Qing-Rong, Drgon, Tomas, Pletnikova, Olga, Walther, Donna, Zhu, Xu-Guang, ...

Neurexins are cell adhesion molecules that help to specify and stabilize synapses and provide receptors for neuroligins, neurexophilins, dystroglycans and α-latrotoxins. We previously reported...

Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs (2007)

Uhl, George R, Liu, Qing-Rong, Drgon, Tomas, Johnson, Catherine, Walther, Donna, Rose, Jed E

Abstract Background Classical genetic studies indicate that nicotine dependence is a substantially heritable complex disorder. Genetic vulnerabilities to nicotine dependence largely overlap with...

SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism (2005)

Lin, Zhicheng, Walther, Donna, Yu, Xiao-Ying, Li, Suxia, Drgon, Tomas, Uhl, George R.

The vesicular monoamine transporter 2 (VMAT2, SLC18A2) takes up cytosolic monoamines into intracellular secretory vesicles, preventing their neurotoxicity in the cytosol and discharging them into...

SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism (2005)

Lin, Zhicheng, Walther, Donna, Yu, Xiao-Ying, Li, Suxia, Drgon, Tomas, Uhl, George R.

The vesicular monoamine transporter 2 (VMAT2, SLC18A2) takes up cytosolic monoamines into intracellular secretory vesicles, preventing their neurotoxicity in the cytosol and discharging them into...

Pooled association genome scanning: Validation and use to identify addiction vulnerability loci in two samples

Liu, Qing-Rong, Drgon, Tomas, Walther, Donna, Johnson, Catherine, Poleskaya, Oxanna, Hess, Judith, ...

Association genome scanning is of increasing interest for identifying the chromosomal regions that contain gene variants that contribute to vulnerability to complex disorders, including addictions....

Polysubstance Abuse–Vulnerability Genes: Genome Scans for Association, Using 1,004 Subjects and 1,494 Single-Nucleotide Polymorphisms

Uhl, George R., Liu, Qing-Rong, Walther, Donna, Hess, Judith, Naiman, Daniel

Strong genetic contributions to drug abuse vulnerability are well documented, but few chromosomal locations for human drug-abuse vulnerability alleles have been confirmed. We now identify chromosomal...

Pooled association genome scanning: Validation and use to identify addiction vulnerability loci in two samples

Liu, Qing-Rong, Drgon, Tomas, Walther, Donna, Johnson, Catherine, Poleskaya, Oxanna, Hess, Judith, ...

Association genome scanning is of increasing interest for identifying the chromosomal regions that contain gene variants that contribute to vulnerability to complex disorders, including addictions....

Polysubstance Abuse–Vulnerability Genes: Genome Scans for Association, Using 1,004 Subjects and 1,494 Single-Nucleotide Polymorphisms

Uhl, George R., Liu, Qing-Rong, Walther, Donna, Hess, Judith, Naiman, Daniel

Strong genetic contributions to drug abuse vulnerability are well documented, but few chromosomal locations for human drug-abuse vulnerability alleles have been confirmed. We now identify chromosomal...

Genome-Wide Association for Nicotine Dependence and Smoking Cessation Success in NIH Research Volunteers

Drgon, Tomas, Montoya, Ivan, Johnson, Catherine, Liu, Qing-Rong, Walther, Donna, Hamer, Dean, ...

Phenotypes related to both nicotine dependence and ability to successfully quit smoking display substantial heritabilities in classical and molecular genetic studies. Twin studies suggest that some...

Genome-Wide Association for Smoking Cessation Success: Participants in a Trial with Adjunctive Denicotinized Cigarettes

Drgon, Tomas, Johnson, Catherine, Walther, Donna, Albino, Anthony P, Rose, Jed E, Uhl, George R

The ability to quit smoking successfully displays substantial heritability in classical and molecular genetic studies. Twin studies suggest that some of the genetics for the ability to quit overlap...