Sarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., ...
Two forms of the activated beta(1)-adrenoceptor exist, one that is stabilized by (-)-noradrenaline and is sensitive to blockade by (-)-propranolol and another which is stabilized by partial agonists...
Sarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., ...
Two forms of the activated beta(1)-adrenoceptor exist, one that is stabilized by (-)-noradrenaline and is sensitive to blockade by (-)-propranolol and another which is stabilized by partial agonists...
Evidence for the existence of the putative [beta]4-adrenoceptor in animal and human heart (1999)
Typescript (photocopy) Includes bibliographical references.
Molenaar, Peter, Sarsero, Doreen, Arch, Jonathan R S, Kelly, John, Henson, Sian M, Kaumann, Alberto J
Chronic treatment of patients with β-blockers causes atrial inotropic hyperresponsiveness through β2-adrenoceptors, 5-HT4 receptors and H2-receptors but apparently not through β1-adrenoceptors...
Validity of (−)-[3H]-CGP 12177A as a radioligand for the ‘putative β4-adrenoceptor' in rat atrium
Sarsero, Doreen, Molenaar, Peter, Kaumann, Alberto J
We have recently suggested the existence in the heart of a ‘putative β4-adrenoceptor' based on the cardiostimulant effects of non-conventional partial agonists, compounds that cause...
Human vascular to cardiac tissue selectivity of L- and T-type calcium channel antagonists
Sarsero, Doreen, Fujiwara, Toshimasa, Molenaar, Peter, Angus, James A
Voltage-operated calcium channel (VOCC) antagonists are effective antihypertensive and antianginal agents but they also depress myocardial contractility.We compared four L-type calcium channel...
Sarsero, Doreen, Molenaar, Peter, Kaumann, Alberto J, Freestone, Nicholas S
We identified putative β4-adrenoceptors by radioligand binding, measured increases in ventricular contractile force by (−)-CGP 12177 and (±)-cyanopindolol and demonstrated increased Ca2+...