Kashef, Jubin, Köhler, Almut, Kuriyama, Sei, Alfandari, Dominique, Mayor, Roberto, Wedlich, Doris
Xenopus Cadherin-11 (Xcad-11) is expressed when cranial neural crest cells (CNC) acquire motility. However, its function in stimulating cell migration is poorly understood. Here, we demonstrate that...
Van Venrooy, Stephanie, Fichtner, Dagmar, Kunz, Martin, Wedlich, Doris, Gradl, Dietmar
Abstract Background As nuclear mediators of wnt/β-catenin signaling, Lef/Tcf transcription factors play important roles in development and disease. Although it is well established, that the four...
Winkler, Christoph, Eggert, Christian, Gradl, Dietmar, Meister, Gunter, Giegerich, Marieke, Wedlich, Doris, ...
Spinal muscular atrophy (SMA) is a motoneuron disease caused by reduced levels of survival motoneuron (SMN) protein. Previous studies have assigned SMN to uridine-rich small nuclear ribonucleoprotein...
Groten, Tanja, Kreienberg, Rolf, Fialka, Irene, Huber, Lukas, Wedlich, Doris
The main clinical features of pre-eclampsia are oedema and vascular leakage. Cadherin-5 mediates endothelial cell–cell contact in the vascular endothelium and may regulate permeability as a...
Münster (Westfalen), Univ., Diss., 1981.
The Wnt/Wg Signal Transducer β-Catenin Controls Fibronectin Expression
Gradl, Dietmar, Kühl, Michael, Wedlich, Doris
β-Catenin stabilizes the cadherin cell adhesion complex but, as a component of the Wnt/Wg signaling pathway, also controls gene expression by forming a heterodimer with a transcription factor of the...
Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK
Unterseher, Frank, Hefele, Joerg A, Giehl, Klaudia, De Robertis, Eddy M, Wedlich, Doris, Schambony, Alexandra
Convergent extension movements occur ubiquitously in animal development. This special type of cell movement is controlled by the Wnt/planar cell polarity (PCP) pathway. Here we show that Xenopus...
Winkler, Christoph, Eggert, Christian, Gradl, Dietmar, Meister, Gunter, Giegerich, Marieke, Wedlich, Doris, ...
Spinal muscular atrophy (SMA) is a motoneuron disease caused by reduced levels of survival motoneuron (SMN) protein. Previous studies have assigned SMN to uridine-rich small nuclear ribonucleoprotein...
The Wnt/Wg Signal Transducer β-Catenin Controls Fibronectin Expression
Gradl, Dietmar, Kühl, Michael, Wedlich, Doris
β-Catenin stabilizes the cadherin cell adhesion complex but, as a component of the Wnt/Wg signaling pathway, also controls gene expression by forming a heterodimer with a transcription factor of the...
Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK
Unterseher, Frank, Hefele, Joerg A, Giehl, Klaudia, De Robertis, Eddy M, Wedlich, Doris, Schambony, Alexandra
Convergent extension movements occur ubiquitously in animal development. This special type of cell movement is controlled by the Wnt/planar cell polarity (PCP) pathway. Here we show that Xenopus...
Winkler, Christoph, Eggert, Christian, Gradl, Dietmar, Meister, Gunter, Giegerich, Marieke, Wedlich, Doris, ...
Spinal muscular atrophy (SMA) is a motoneuron disease caused by reduced levels of survival motoneuron (SMN) protein. Previous studies have assigned SMN to uridine-rich small nuclear ribonucleoprotein...
LI-Cadherin–mediated Cell–Cell Adhesion Does Not Require Cytoplasmic Interactions
Kreft, Bertolt, Berndorff, Dietmar, Böttinger, Anja, Finnemann, Silvia, Wedlich, Doris, Hortsch, Michael, ...
The adhesive function of classical cadherins depends on the association with cytoplasmic proteins, termed catenins, which serve as a link between cadherins and the actin cytoskeleton. LI-cadherin, a...