Douglas J. Schwartzentruber

Treatment of Patients With Metastatic Melanoma With Autologous Tumor-Infiltrating Lymphocytes and Interleukin 2 (1994)

Rosenberg, Steven A., Yannelli, John R., Yang, James C., Topalian, Suzanne L., Schwartzentruber, Douglas J., Weber, Jeffrey S., ...

Background: Studies of human tumor-infiltrating lymphocytes (TILs) derived from patients with a variety of histologic types of cancer have demonstrated that cellular immune reactions against...

Prospective Randomized Trial of High-Dose Interleukin-2 Alone or in Conjunction With Lymphokine-Activated Killer Cells for the Treatment of Patients With Advanced Cancer (1993)

Rosenberg, Steven A., Lotze, Michael T., Yang, James C., Topalian, Suzanne L., Chang, Alfred E., Schwartzentruber, Douglas J., ...

Background: Treatment using interleukin-2 (IL-2) alone or in conjunction with lymphokine-activated killer (LAK) cells has been shown to mediate disease regression in selected patients with advanced...

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

Phan, Giao Q., Yang, James C., Sherry, Richard M., Hwu, Patrick, Topalian, Suzanne L., Schwartzentruber, Douglas J., ...

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a critical immunoregulatory molecule (expressed on activated T cells and a subset of regulatory T cells) capable of down-regulating T cell...

Hepatic Abscess in Patients With Chronic Granulomatous Disease

Lublin, Matthew, Bartlett, David L., Danforth, David N., Kauffman, Howard, Gallin, John I., Malech, Harry L., ...

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

Phan, Giao Q., Yang, James C., Sherry, Richard M., Hwu, Patrick, Topalian, Suzanne L., Schwartzentruber, Douglas J., ...

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a critical immunoregulatory molecule (expressed on activated T cells and a subset of regulatory T cells) capable of down-regulating T cell...

Hepatic Abscess in Patients With Chronic Granulomatous Disease

Lublin, Matthew, Bartlett, David L., Danforth, David N., Kauffman, Howard, Gallin, John I., Malech, Harry L., ...

Identification of Dynamically Distinct Subpopulations of T Lymphocytes That Are Differentially Affected by HIV

Kovacs, Joseph A., Lempicki, Richard A., Sidorov, Igor A., Adelsberger, Joseph W., Herpin, Betsey, Metcalf, Julia A., ...

We examined the effects of human immunodeficiency virus infection on the turnover of CD4 and CD8 T lymphocytes in 17 HIV-infected patients by 30 min in vivo pulse labeling with bromodeoxyuridine...