Pathogenesis of aerosolized Eastern Equine Encephalitis virus infection in guinea pigs (2009)
Roy, Chad J, Reed, Douglas S, Wilhelmsen, Catherine L, Hartings, Justin, Norris, Sarah, Steele, Keith E
Abstract Mice and guinea pigs were experimentally exposed to aerosols containing regionally-distinct strains (NJ1959 or ArgM) of eastern equine encephalitis virus (EEEV) at two exclusive particle...
Rubins, Kathleen H, Hensley, Lisa E, Wahl-Jensen, Victoria, Daddario DiCaprio, Kathleen M, Young, Howard A, Reed, Douglas S, ...
Abstract Background Infection with Ebola virus (EBOV) causes a fulminant and often fatal hemorrhagic fever. In order to improve our understanding of EBOV pathogenesis and EBOV-host interactions, we...
Marburg and Ebola Viruses as Aerosol Threats (1998)
Leffel, Elizabeth K., Reed, Douglas S.
Ebola and Marburg viruses are the sole members of the genus Filovirus in the family Filoviridae. There has been considerable media attention and fear generated by outbreaks of filoviruses because...
Pathogenesis of Ebola Hemorrhagic Fever in Cynomolgus Macaques (1998)
Geisbert, Thomas W., Hensley, Lisa E., Larsen, Tom, Young, Howard A., Reed, Douglas S.
Ebola virus (EBOV) infection causes a severe and fatal hemorrhagic disease that in many ways appears to be similar in humans and nonhuman primates; however, little is known about the development of...
Reed, Douglas S., Lind, Cathleen M., Lackemeyer, Matthew G., Sullivan, Lawrence J., Pratt, William D., Parker, Michael D.
Two live, attenuated strains of Venezuelan equine encephalitis virus (VEE), IE1150K and V3526, were administered to macaques to determine if they could elicit protection against an aerosol challenge...
Reed, Douglas S., Smoll, Jennifer
This report covers the utility of respiratory vaccination with recombinant subunit vaccines for protection against pneumonic plague.
Reed, Douglas S., Larsen, Tom, Sullivan, Lawrence J., Lind, Cathleen M., Lackemeyer, Matthew G., Pratt, William D., ...
Cynomolgus macaques were exposed by aerosol to a virulent strain of western equine encephalitis virus (WEEV). Between 4 and 6 days after exposure, macaques had a significantly elevated temperature...
Reed, Douglas S., Martinez, Mark J.
Mice were vaccinated with a recombinant fusion protein, rF1-V, by an intramuscular prime followed by an intranasal boost, to evaluate protection against pneumonic plague. Forty-two days after the...
Reed, Douglas S., Martinez, Mark J.
Mice were vaccinated with a recombinant fusion protein, rF1-V, by an intramuscular prime followed by an intranasal boost, to evaluate protection against pneumonic plague. Forty-two days after the...
Nonhuman Primate Models of Aerosol Exposure to Alphaviruses (1998)
Equine encephalitis viruses are alphaviruses normally transmitted through mosquito bites. Both mosquito borne Venezuelan equine encephalitis virus (VEEV) and Western equine encephalitis virus (WEEV)...
A Nonhuman Primate Model for Aerosol Infection With Western Equine Encephalitis Viruses (1998)
Reed, Douglas S., Larsen, Thomas, Wilhelmsen, Catherine, Pratt, William, Lind, Cathleen, Parker, Michael
While Western Equine Encephalitis Viruses produce an incapacitating but rarely fatal illness in humans when resulting from a mosquito bite, laboratory accidents suggest a 40 % mortality rate when...
Thesis (Ph. D.)--Yale University, 1995.
UMI order number 9540607.
Democracy v. equality : legal and political struggles over school finance equalization /
Typescript.
Kim, Sung-Kwon, Reed, Douglas S., Olson, Sara, Schnell, Matthias J., Rose, John K., Morton, Phillip A., ...
We compared peripheral and mucosal primary CD8 T cell responses to inflammatory and noninflammatory forms of antigen in a T cell-adoptive transfer system. Immunization with the soluble antigen,...
Kim, Sung-Kwon, Reed, Douglas S., Olson, Sara, Schnell, Matthias J., Rose, John K., Morton, Phillip A., ...
We compared peripheral and mucosal primary CD8 T cell responses to inflammatory and noninflammatory forms of antigen in a T cell-adoptive transfer system. Immunization with the soluble antigen,...
Geisbert, Thomas W., Hensley, Lisa E., Larsen, Tom, Young, Howard A., Reed, Douglas S., Geisbert, Joan B., ...
Ebola virus (EBOV) infection causes a severe and fatal hemorrhagic disease that in many ways appears to be similar in humans and nonhuman primates; however, little is known about the development of...
Rubins, Kathleen H, Hensley, Lisa E, Wahl-Jensen, Victoria, Daddario DiCaprio, Kathleen M, Young, Howard A, Reed, Douglas S, ...
Primate blood cells were analysed for changes in global gene expression patterns at several time points following infection with Ebola virus, providing insights into potential mechanisms of viral...
Rossi, Cynthia A., Ulrich, Melanie, Norris, Sarah, Reed, Douglas S., Pitt, Louise M., Leffel, Elizabeth K.
In 2001, a bioterrorism attack involving Bacillus anthracis spore-laced letters resulted in 22 cases of inhalation anthrax, with five fatalities. This incident identified gaps in our health care...
Pathogenesis of aerosolized Eastern Equine Encephalitis virus infection in guinea pigs
Roy, Chad J, Reed, Douglas S, Wilhelmsen, Catherine L, Hartings, Justin, Norris, Sarah, Steele, Keith E
Mice and guinea pigs were experimentally exposed to aerosols containing regionally-distinct strains (NJ1959 or ArgM) of eastern equine encephalitis virus (EEEV) at two exclusive particle size...