Duong P. Huynh

The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI (2003)

Huynh, Duong P., Scoles, Daniel R, Nguyen, Dung, Pulst, Stefan M

Inactivating mutations of the gene encoding parkin are responsible for some forms of autosomal recessive juvenile Parkinson disease. Parkin is an ubiquitin ligase that ubiquitinates misfolded...

Expansion of the polyQ repeat in ataxin-2 alters its Golgi localization, disrupts the Golgi complex and causes cell death (2003)

Huynh, Duong P., Yang, Hai-Tao, Vakharia, Hema, Nguyen, Dung, Pulst, Stefan M.

Spinocerebellar ataxia type 2 (SCA2) is caused by the expansion of a polyglutamine (polyQ) repeat in ataxin-2, the SCA2 gene product. In contrast to other polyQ diseases, intranuclear inclusions are...

The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI (2003)

Huynh, Duong P., Scoles, Daniel R., Nguyen, Dung, Pulst, Stefan M.

Inactivating mutations of the gene encoding parkin are responsible for some forms of autosomal recessive juvenile Parkinson disease. Parkin is a ubiquitin ligase that ubiquitinates misfolded proteins...

The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI (2003)

Huynh, Duong P., Scoles, Daniel R, Nguyen, Dung, Pulst, Stefan M

Inactivating mutations of the gene encoding parkin are responsible for some forms of autosomal recessive juvenile Parkinson disease. Parkin is an ubiquitin ligase that ubiquitinates misfolded...

A novel protein with RNA-binding motifs interacts with ataxin-2 (2000)

Shibata, Hiroki, Huynh, Duong P., Pulst, Stefan-M.

Spinocerebellar ataxia type 2 (SCA2) is caused by expansion of a polyglutamine tract in ataxin-2, a protein of unknown function. Using the yeast two-hybrid system, we identified a novel protein,...

Alternative transcripts in the mouse neurofibromatosis type 2 (NF2) gene are conserved and code for schwannomins with distinct C-terminal domains (1994)

Huynh, Duong P., Nechiporuk, Tamilla, Pulst, Stefan-M.

Mutations in the neurofibromatosis type 2 (NF2) gene predispose individuals to the development of nervous system tumors and ocular abnormalities. The NF2 gene product, schwannomin, is a member of a...

Mutations of the neurofibromatosis type 2 gene and lack of the gene product in vestibular schwannomas (1994)

Sainz, Jesús, Huynh, Duong P., Figueroa, Karla, Ragge, Nikola K., Baser, Michael E., Pulst, Stefan-Matthias

Schwannomas are common tumors of the nervous system and are frequently found in patients with neurofibromatosis (NF) 2. Although loss of heterozygosity in NF2 tumors suggests that the NF2 gene...

Dissociated Fear and Spatial Learning in Mice with Deficiency of Ataxin-2

Huynh, Duong P., Maalouf, Marwan, Silva, Alcino J., Schweizer, Felix E., Pulst, Stefan M.

Mouse models with physiological and behavioral differences attributable to differential plasticity of hippocampal and amygdalar neuronal networks are rare. We previously generated ataxin-2 (Atxn2)...