E. A. Cohen

Publication List Details

Period

1966 - 2008

Number

107

Co-Authors

MILLIMETERWAVE AND FOURIER-TRANSFORM EMISSION SPECTRA OF THE BiS RADICAL (2008)

Izumi, K., Kawaguchi, K., Cohen, E. A., Setzer, K. D., Fink, E. H.

E. A. Cohen, D. M. Goodridge, K. Kawaguchi, E. H. Fink, and K. D. Setzer, J. Mol. Spectrosc. 239 (2006) 16-23.H. M. Pickett, J. Mol. Spectrosc. 148 (1991) 271-377.

( Submillimeter, Millimeter, and Microwave Spectral Line Catalog (2007)

H. Hfl Piciwtt, R. L. I’oynter, E. A. Cohen, Hfl L. Delitsky, J. C. Pearson

This paper clescribes a computer-accessible catalog of sutxnillimcter, millimeter, and microwave spectral lines in the frequency range between O alld 10,000 GHz (i.e., wavelengths longer than 30 jm)....

C. I. Frum (2007)

Oh Cohen And, Rotational Spectra, C. I. Frum, J. J. Oh, E. A. Cohen

The rotational spectra of the ground states of calcium and have been recorded in absorption between 250 and 700 The gas phase free radicals have been produced in a ceramic furnace by the reaction of...

Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum. (2007)

Binette, J., Dube, M., Mercier, J., Cohen, E. A.

BACKGROUND: HIV-1 Vpu targets newly synthesized CD4 receptor for rapid degradation by a process reminiscent of endoplasmic reticulum (ER)-associated protein degradation (ERAD). Vpu is thought to act...

Rotational Spectra of the X states of CaH and CaD (2004)

Frum, C.I., Oh, J.J., Cohen, E.A., Pickett, H.M.

The molecular constants including the rotaional constant, centrifugal distortion constants, spin-rotation constants, and magnetic hyperfine interaction constants have been extrcted from the spectra.

The Isotope Effect of the O2a1g Rotational Constant (2004)

Cohen, E. A., Okunishi, M., Oh, J. J.

The pure rotational spectrum of a1g oxygen in its first excited vibrational state as well as the ground vibrational state rotational spectra of 16O18O and 18O2 in their a states have been observed.

The Rotational Spectra, Hyperfine Interactions, and 17o Magnetic Shieldings of 17O16O16O,16O17O16OO, and 17OS16O (2004)

Cohen, E. A., Hillig, K. W. II, Pickett, H. M.

Measurements of the rotational spectra of 17O16O16O and 16O17O16O have been extended to allow determination of a complete set of sextic centrifugal distortion constants for both molecules.

The Rotational Spectrum and Molecular Structure of Chlorine Chlorate (2004)

Friedl, R. R., Birk, M., Oh, J. J., Cohen, E. A.

Cl2O3 has been indentified as a product of the ClO+OClO+M reaction at 220K using submillimeter spectroscopy of the reaction products in a flowing gas mixture. The spectra of all four Ci isotopic...

Pressure Broadening of ClO by N2 and O2 Near 204 and 649 GHz and New Frequency Measurements Between 632 and 725 GHz (2004)

Oh, J. J., Cohen, E. A.

The N2 and O2 pressure broadenings of the CIO transitions near 204 and 649 GHz have been measured between 200 and 300 K. Oxygen broadening has been measured for the transitions near 278 GHz.

The Nu-Sub-One Band of HOBr (2004)

Cohen, E.A., McRae, G.A., Tan, A.T.L., Friedl, R.R., Johns, J.W.C.

The Nu-Sub-One Band of HOBr centered at 3614.903 cm-1 has been observed at 0.006 cm-1 resolution. (abstract only)

The n11 Band of HOBr (2004)

Cohen, E. A.

The n1 band of HOBr centered at 3614.903 cm-1 has been observed at 0.006 cm-1 resolution. The band is a hybrid type with The spectra of both bromine isotopes have been simultaneously fitted with a...

(abstract) BrO and HOBr: New Results for Familiar Molecules (2004)

Cohen, E. A., Müller, H. S. P., Tan, T. L., McRae, G. A., Johns, J. W. C.

As part of a program at our laboratory to extend the spectroscopic database of the halogen oxides and oxo-acids which participate in atmospheric ozone chemistry, we have continued the investigations...

Millimeter and submillimeter spectroscopy in support of upper atmospheric research (2004)

Cohen, E. A.

This paper describes the laboratory program in millimeter and submillimeter spectroscopy at the Jet Propulsion Laboratory.

Microwave, millimeter, submillimeter and far infrared spectral databases (2004)

Pearson, J. C., Pickett, H. M., Drouin, B. J., Chen, P., Cohen, E. A.

The JPL Submillimeter, Millimeter and Microwave Spectral Line Catalog is an attempt to compile a complete and consistent set of spectroscopic data to support observations and observation planning.

FAR INFRARED AND MILLIMETER WAVE SPECTRA OF THE TORSIONALLY EXCITED STATES OF PERCHLORIC ACID, $HClO_{4}$. (2003)

Cohen, E. A., Drouin, Brian J., Oh, J. J., Johnson, Matthew S., Nelander, B.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology; Department of Chemistry, SookMyung Women's University; Department of Chemistry, University of Copenhagen; Department...

THE SUB-MILLIMETERWAVE ROTATIONAL SPECTRUM OF SULFURIC ACID (2003)

Drouin, Brian J., Cohen, E. A.

$^{a}$R. L. Kuczkowski, R. D. Suenram, F. J. Lovas J. Am. Chem. Soc. 103(10), 2561-2566, 1981 $^{b}$D. L. Fiacco, S. W. Hunt, K. R. Leopold J. Am. Chem. Soc. 124(16), 4504-4511, 2002

ATMOSPHERIC TRACE GAS ROTATIONAL LINESHAPE PARAMETERS NEAR 600 GHz (2001)

Drouin, Brian J., Cohen, E. A.

Author Institution: California Institute of Technology; Jet Propulsion Laboratory, California Institute of Technology

FURTHER STUDIES OF THE PERCHLORIC ACID ROTATIONAL SPECTRUM (2001)

Cohen, E. A., Oh, J. J., Drouin, Brian J.

$^{a}$Present address: Department of Chemistry, SookMyung Women's University, Seoul, Korea

RNA trafficking signals in human immunodeficiency virus type 1 (2001)

Mouland, A. J., Xu, H. B., Cui, H. Y., Krueger, W., Munro, T. P., Prasol, M., ...

Intracellular trafficking of retroviral RNAs is a potential mechanism to target viral gene expression to specific regions of infected cells. Here we show that the human immunodeficiency virus type 1...

RNA trafficking signals in human immunodeficiency virus type 1 (2001)

Mouland, A. J., Xu, H. B., Cui, H. Y., Krueger, W., Munro, T. P., Prasol, M., ...

Intracellular trafficking of retroviral RNAs is a potential mechanism to target viral gene expression to specific regions of infected cells. Here we show that the human immunodeficiency virus type 1...

NEW RESULTS FROM THE ROTATIONAL SPECTRA OF THE HALOGEN MONOXIDES. INTERATOMIC POTENTIALS, FINE AND HYPERFINE INTERACTIONS. (2000)

Drouin, Brian J., Cohen, E. A., Miller, Charles E., Müller, Holger S. P.

$^{a}$J. M. Brown and J. K. G. Watson, J. Mol. Spec. 148, 371(1991). $^{b}$P. Pyykk\""o, M. Seth, Theor. Chem. Acc. 96, 92-104(1997) $^{c}$I. Lindgren and A. Ros\'en. Case Studies in Atomic Physics,...

THE ROTATIONAL SPECTRA OF THE $X_{1}{^{2}}\Pi_{1/2}$ and $X_{2}{^{2}} \Pi_{3/2}$ STATES OF BiO (2000)

Cohen, E. A., Goodridge, Damian M., Kawaguchi, K.

$^{a}$Present address: Okayama University, Faculty of Science, Tsushimanaka 3-1-1, Okayama, 700-8530, Japan. $^{b}$O. Shestakov, R. Breidohr, H. Demes, K. D. Setzer and E. H. Fink J. Mol. Spectrosc....

SPECTROSCOPY OF CHLOROSYL FLUORIDE, FClO (1999)

Müller, Holger S. P., Cohen, E. A.

$^{a}$ H.S.P. M\""{u}ller, paper MF04, presented at The 53rd Ohio State University International Symposium on Molecular Spectroscopy, Columbus, OH, June 1998

THE ROTATIONAL SPECTRA OF IO $X ^{2}\Pi_{3/2}$ IN VIBRATIONAL LEVELS $v = 0$ TO $v = 12$ (1998)

Miller, Charles E., Cohen, E. A.

Author Institution: Department of Chemistry, Haverford College; Jet Propulsion Laboratory, California Institute of Technology

THE ROTATIONAL SPECTRUM AND MOLECULAR PROPERTIES OF CHLORYL CHLORIDE, C1C1$O_{2}$ (1997)

Müller, Holger S. P., Cohen, E. A.

$^{a}$T.J. Lee, C. McMichael Rohlfing, and J.E. Rice, J. Chem, Phys., \textbf{97}, 6593, (1992) $^{b}$C.J. Pursell. J. conyers, and C. Denison, J. Phys. Chem., \textbf{100}, 15450, (1996) $^{c}$J.D....

FURTHER INVESTIGATIONS OF THE BrO ROTATIONAL SPECTRUM (1996)

Cohen, E. A., Müller, Holger S. P.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

THE $\nu_{1}$ and $\nu_{2}$ BANDS OF DOBr AND THE ROTATIONAL SPECTRA OF THE $\nu_{2} = 1$ AND $\nu_{3} = 1$ STATES (1996)

Cohen, E. A., Müller, Holger S. P., Tan, T. L., McRae, G. A., Johns, J. W. C., Noel, M.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology; Department of Physics, Faculty of Science; Atomic Energy of Canada Limited, Chalk River Laboratories; Steacie...

SPECTROSCOPY OF BROMINE DIOXIDE, OBrO (1996)

Müller, Holger S. P., Miller, Charles E., Cohen, E. A.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

THE $\nu_{1}$ BAND OF HOBr (1995)

Cohen, E. A., McRae, G. A., Tan, T. L., Friedl, R. R., Johns, J. W. C., Noel, M.

Author Institution: California Institute of Technology, Pasadena, California 91109.; Chalk River Laboratories, Chalk River, Ontario KOJ IJO, Canada.; "Faculty of Science, National University of...

THE SUBMILLIMETER SPECTRUM OF $Br_{2}O$ (1995)

Müller, Holger S. P., Cohen, E. A.

Author Institution: California Institute of Technology, Pasadena, California 91109.

PRESSURE BROADENING OF ClO AND OZONE LINES BY NITROGEN AND OXYGEN - APPLICATION TO UPPER ATMOSPHERIC MEASUREMENTS (1993)

Oh, J. J., Read, W. G., Cohen, E. A.

$^{1}$ J. W. Waters, Proc. IEEE, 80, 1679-1701 (1992) $^{2}$ J. J. Oh and E. A. Cohen, JQSRT, 48, 405-408(1992)

THE ROTATIONAL SPECTRUM OF PERCHLORIC ACID, $HCIO_{4}$ (1992)

Oh, J. J., Cohen, E. A.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

MOLECULAR PARAMETERS FOR THE $COF_{2}$ BANDS NEAR 16.6$\mu$ AND 5.2$\mu$ (1992)

Cohen, E. A., Oh, J. J., Brown, L. R., Peterson, D. B., May, R. D.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

THE ROTATIONAL SPECTRUM AND STRUCTURE OF $Cl_{2}0_{3}$ (1990)

Birk, M., Friedl, R. R., Cohen, E. A.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

Quantitative Analysis of the Products of the ClO Self Reaction at Low Temperature (1990)

Birk, Manfred, Friedl, R. R., Cohen, E. A.

The relative intensities of individual rotational absorption lines of ClOCl, ClO, ClOOCl and OClO have been measured in the submillimeter wave region around 400 GHz. Stark measurements were taken to...

ASSIGNMENT OF THE $\nu_{1}$ AND $2\nu_{2}$ BANDS OF $COF_{2}$ AT $5.2 \mu M$ (1989)

Brown, L. R., Cohen, E. A.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

THE MICROWAVE SPECTRUM OF AlO (1989)

Yamada, Chikashi, Fujitake, Masaharu, Hirota, Eizi, Cohen, E. A.

Author Institution: Institute for Molecular Science; Jet Propulsion Laboratory, California Institute of Technology

THE VIBRATIONAL AND ROTATIONAL SPECTRA OF OZONE FOR THE (0,1,0) AND (0,2,0) STATES (1987)

Pickett, H. M., Cohen, E. A., Brown, L. R., Rinsland, C. P., Smith, M. A. H., Devi, V. Malathy, ...

Author Institution: Jet Propulsion Laboratory, California Institute of Technology; Atmospheric Sciences Division, NASA Langley Research Center; Department of Physics, College of William and Mary;...

THE ROTATIONAL SPECTRUM, STRUCTURE AND DIPOLE MOMENT OF ETHYNYLPHOSPHINE. $H_{2}PC\equiv CH$ (1987)

Cohen, E. A., McRae, G. A., Stefano, S. Di, Beaudet, R. A., Goldwhite, H.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive; Center for the Study of Fast Transient Processes, Department of Chemistry, University of...

THE $\nu_{2}$ BAND OF HOBr (1986)

Cohen, E. A., McRae, G. A.

Address of Cohen and McRae: Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, California 91109, USA

GENERATION OF TUNABLE LASER SIDEBANDS IN THE FAR-INFRARED REGION (1985)

Pickett, H. M., Farhoomand, J., Blake, Geoffrey A., Frerking, M. A., Cohen, E. A.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology; Jet Propulsion Laboratory, California Institute of Technology; Department of Chemistry, California Institute of...

MEASUREMENT OF ABSOLUTE ABSORPTION AND LINESHAPE OF CO AT 115 GHz (1985)

Read, W. G., Cohen, E. A., Pickett, H. M.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology; Department of Chemistry, University of Michigan; Jet Propulsion Laboratory, California Institute of Technology; Jet...

PURE ROTATION AND ROTATION-VIBRATION SPECTRA OF OZONE (1984)

Cohen, E. A., Pickett, H. M., Margolis, J. S., Chiu, C.

The research described in this paper was performed by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

ROTATION-INVERSION SPECTRUM OF CYANAMIDE (1984)

Read, W. G., Cohen, E. A., Pickett, H. M.

The research described in this paper was performed by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

ROTATIONAL SPECTRA OF 16-17-16 AND $17-16-16$ $0_{3}$ (1983)

Cohen, E. A., Pickett, H. M.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

ROTATIONAL SPECTRA OF VIBRATIONALLY EXCITED OZONE (1983)

Pickett, H. M., Cohen, E. A.

Author Institution: Jet Propulsion Laboratory, California Institute of Technology

APPLICATIONS OF A CONVOLUTION TECHNIQUE FOR MEASURING LINEWIDTHS AND SHIFTS (1981)

Pickett, H. M., Brinza, D. E., Cohen, E. A.

Work described in this abstract was carried out by JPL, Caltech contract with NASA.

THE ROTATION-INVERSION SPECTRUM OF $NH_{2}O$ (1981)

Cohen, E. A., Pickett, H. M.

Work described in this abstract was carried out by JPL, Caltech under contract with NASA.

THE ROTATIONAL SPECTRUM OF NO (1979)

Pickett, H. M., Cohen, E. A., Waters, J. W., Phillips, T. G.

This work was performed and presents the results of one phase of research carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract NAS 7-100, sponsored by the...

THE MILLIMETER SPECTRUM AND MOLECULAR PARAMETERS OF ClO IN THE v = 0 AND v = 1 VIBRATIONAL STATES (1977)

Cohen, E. A., Kakar, Ramesh K.

$^{1}$W. Meerts, Chem. Phys. 14, 421 (1976). $^{2}$T. Amano, S. Saito, E. Hirota, Y. Morino, D. R. Johnston, and F. X. Powell, J. Mol. Spectrosc. 30, 275 (1969). $^{3}$R. Menzies, J. S. Margolis, E....

THE STARK EFFECT OF THE $\nu_{4} = 1$ LEVEL OF $NH_{3}$ -- AN INDICATION OF CORIOLIS INTERACTION BETWEEN THE $\nu_{4}$ AND $2\nu_{2}$ VIBRATIONS (1974)

Cohen, E. A., Kwan, Y. Y.

This paper presents the results of one phase of research carried out at the Jet Propulsion Laboratory, California Institute of Technology, under Contract Number MAS 7-100, sponsored by the National...

THE INVERSION SPECTRUM OF $NH_{3}$ IN THE ${000}^{0}1^{1}$ STATE (1972)

Cohen, E. A., Poynter, R. L.

This research was supported under NASA Contract No. NAS 7-100. The authors also wish to thank the Pomona Operation, Electrodynamics Division, General Dynamics Corporation for use of its spectrometer....

THE MICROWAVE SPECTRUM OF 1-METHYLPENTABORANE (9) (1966)

Cohen, E. A., Beaudet, R. A.

This work was supported by Air Force Office of Scientific Research Grant \# AS-AFOSR-849-65, and the Research Corporation.

Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses.

Göttlinger, H G, Dorfman, T, Cohen, E A, Haseltine, W A

The Vpu protein of human immunodeficiency virus type 1 facilitates the release of virus particles from the surface of infected cells. The ability of the Vpu protein to facilitate release of Gag...

The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles.

Kondo, E, Mammano, F, Cohen, E A, Göttlinger, H G

The vpr gene of human immunodeficiency virus type 1 (HIV-1) encodes a virion-associated regulatory protein. Mutagenesis has shown that the virion association of Vpr requires sequences near the C...

Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.

Yao, X J, Subbramanian, R A, Rougeau, N, Boisvert, F, Bergeron, D, Cohen, E A

The Vpr gene product of human immunodeficiency virus type 1 is a virion-associated protein that is important for efficient viral replication in nondividing cells such as macrophages. At the cellular...

Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule.

Tiganos, E, Yao, X J, Friborg, J, Daniel, N, Cohen, E A

The human immunodeficiency virus type 1 (HIV-1) vpu gene encodes a 16-kDa class I integral membrane phosphoprotein with an N-terminal membrane-spanning region and a C-terminal cytoplasmic domain. In...

Two distinct oncornaviruses harbor an intracytoplasmic tyrosine-based basolateral targeting signal in their viral envelope glycoprotein.

Lodge, R, Delamarre, L, Lalonde, J P, Alvarado, J, Sanders, D A, Dokhélar, M C, ...

It has been clearly established that the budding of the human immunodeficiency virus (HIV-1), a lentivirus, occurs specifically through the basolateral membrane in polarized epithelial cells. More...

The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells.

Lodge, R, Göttlinger, H, Gabuzda, D, Cohen, E A, Lemay, G

Human immunodeficiency virus type 1 (HIV-1) has been shown to exhibit a specific basolateral release in polarized epithelial cells. Previous investigators have used vaccinia virus recombinants...

Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles.

Lavallée, C, Yao, X J, Ladha, A, Göttlinger, H, Haseltine, W A, Cohen, E A

The human immunodeficiency virus type 1 (HIV-1) particles consists of two molecules of genomic RNA as well as molecules originating from gag, pol, and env products, all synthesized as precursor...

Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export.

Yao, X J, Göttlinger, H, Haseltine, W A, Cohen, E A

The effect of vpu on the release of human immunodeficiency type 1 capsid proteins was examined in the presence or absence of virus-encoded envelope glycoproteins as well as in cells which...

Human immunodeficiency virus vpr product is a virion-associated regulatory protein.

Cohen, E A, Dehni, G, Sodroski, J G, Haseltine, W A

The vpr product of the human immunodeficiency virus type 1 (HIV-1) acts in trans to accelerate virus replication and cytopathic effect in T cells. Here it is shown that the HIV-1 viral particle...

Neutralization of herpes simplex virus ribonucleotide reductase activity by an oligopeptide-induced antiserum directed against subunit H2.

Cohen, E A, Gaudreau, P, Brazeau, P, Langelier, Y

Herpes simplex virus type 1 ribonucleotide reductase is associated with two polypeptides of apparent molecular weights 136,000 and 38,000. The two polypeptides form a tight complex and, therefore,...

Identification of viral polypeptides involved in pseudorabies virus ribonucleotide reductase activity.

Cohen, E A, Paradis, H, Gaudreau, P, Brazeau, P, Langelier, Y

We studied pseudorabies virus-induced ribonucleotide reductase and found that it exhibited biochemical properties very similar to those of herpes simplex virus reductase. A polyclonal rabbit...

Functional role of human immunodeficiency virus type 1 vpu.

Terwilliger, E F, Cohen, E A, Lu, Y C, Sodroski, J G, Haseltine, W A

To investigate the role of vpu in the replication and cytopathicity of human immunodeficiency virus type 1 (HIV-1), infectious proviruses were constructed that were isogenic except for the ability to...

Mutational analysis of the 5' non-coding region of human immunodeficiency virus type 1: effects of secondary structure on translation.

Parkin, N T, Cohen, E A, Darveau, A, Rosen, C, Haseltine, W, Sonenberg, N

The first 111 nt from the 5' end of human immunodeficiency virus type 1 (HIV-1) mRNAs are shown to have a strong inhibitory effect on the translation of mRNA in in vitro translation extracts as well...

The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells.

Lodge, R, Lalonde, J P, Lemay, G, Cohen, E A

Budding of retroviruses from polarized epithelial Madin-Darby canine kidney cells (MDCK) takes place specifically at the basolateral membrane surface. This sorting event is suspected to require a...

Fairness in the coronary angiography queue

Alter, D A, Basinski, A S, Cohen, E A, Naylor, C D

BACKGROUND: Since waiting lists for coronary angiography are generally managed without explicit queuing criteria, patients may not receive priority on the basis of clinical acuity. The objective of...

Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses.

Göttlinger, H G, Dorfman, T, Cohen, E A, Haseltine, W A

The Vpu protein of human immunodeficiency virus type 1 facilitates the release of virus particles from the surface of infected cells. The ability of the Vpu protein to facilitate release of Gag...

The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles.

Kondo, E, Mammano, F, Cohen, E A, Göttlinger, H G

The vpr gene of human immunodeficiency virus type 1 (HIV-1) encodes a virion-associated regulatory protein. Mutagenesis has shown that the virion association of Vpr requires sequences near the C...

Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.

Yao, X J, Subbramanian, R A, Rougeau, N, Boisvert, F, Bergeron, D, Cohen, E A

The Vpr gene product of human immunodeficiency virus type 1 is a virion-associated protein that is important for efficient viral replication in nondividing cells such as macrophages. At the cellular...

Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule.

Tiganos, E, Yao, X J, Friborg, J, Daniel, N, Cohen, E A

The human immunodeficiency virus type 1 (HIV-1) vpu gene encodes a 16-kDa class I integral membrane phosphoprotein with an N-terminal membrane-spanning region and a C-terminal cytoplasmic domain. In...

Two distinct oncornaviruses harbor an intracytoplasmic tyrosine-based basolateral targeting signal in their viral envelope glycoprotein.

Lodge, R, Delamarre, L, Lalonde, J P, Alvarado, J, Sanders, D A, Dokhélar, M C, ...

It has been clearly established that the budding of the human immunodeficiency virus (HIV-1), a lentivirus, occurs specifically through the basolateral membrane in polarized epithelial cells. More...

The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells.

Lodge, R, Göttlinger, H, Gabuzda, D, Cohen, E A, Lemay, G

Human immunodeficiency virus type 1 (HIV-1) has been shown to exhibit a specific basolateral release in polarized epithelial cells. Previous investigators have used vaccinia virus recombinants...

Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles.

Lavallée, C, Yao, X J, Ladha, A, Göttlinger, H, Haseltine, W A, Cohen, E A

The human immunodeficiency virus type 1 (HIV-1) particles consists of two molecules of genomic RNA as well as molecules originating from gag, pol, and env products, all synthesized as precursor...

Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export.

Yao, X J, Göttlinger, H, Haseltine, W A, Cohen, E A

The effect of vpu on the release of human immunodeficiency type 1 capsid proteins was examined in the presence or absence of virus-encoded envelope glycoproteins as well as in cells which...

Human immunodeficiency virus vpr product is a virion-associated regulatory protein.

Cohen, E A, Dehni, G, Sodroski, J G, Haseltine, W A

The vpr product of the human immunodeficiency virus type 1 (HIV-1) acts in trans to accelerate virus replication and cytopathic effect in T cells. Here it is shown that the HIV-1 viral particle...

Neutralization of herpes simplex virus ribonucleotide reductase activity by an oligopeptide-induced antiserum directed against subunit H2.

Cohen, E A, Gaudreau, P, Brazeau, P, Langelier, Y

Herpes simplex virus type 1 ribonucleotide reductase is associated with two polypeptides of apparent molecular weights 136,000 and 38,000. The two polypeptides form a tight complex and, therefore,...

Identification of viral polypeptides involved in pseudorabies virus ribonucleotide reductase activity.

Cohen, E A, Paradis, H, Gaudreau, P, Brazeau, P, Langelier, Y

We studied pseudorabies virus-induced ribonucleotide reductase and found that it exhibited biochemical properties very similar to those of herpes simplex virus reductase. A polyclonal rabbit...

Functional role of human immunodeficiency virus type 1 vpu.

Terwilliger, E F, Cohen, E A, Lu, Y C, Sodroski, J G, Haseltine, W A

To investigate the role of vpu in the replication and cytopathicity of human immunodeficiency virus type 1 (HIV-1), infectious proviruses were constructed that were isogenic except for the ability to...

Mutational analysis of the 5' non-coding region of human immunodeficiency virus type 1: effects of secondary structure on translation.

Parkin, N T, Cohen, E A, Darveau, A, Rosen, C, Haseltine, W, Sonenberg, N

The first 111 nt from the 5' end of human immunodeficiency virus type 1 (HIV-1) mRNAs are shown to have a strong inhibitory effect on the translation of mRNA in in vitro translation extracts as well...

The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells.

Lodge, R, Lalonde, J P, Lemay, G, Cohen, E A

Budding of retroviruses from polarized epithelial Madin-Darby canine kidney cells (MDCK) takes place specifically at the basolateral membrane surface. This sorting event is suspected to require a...

Fairness in the coronary angiography queue

Alter, D A, Basinski, A S, Cohen, E A, Naylor, C D

BACKGROUND: Since waiting lists for coronary angiography are generally managed without explicit queuing criteria, patients may not receive priority on the basis of clinical acuity. The objective of...