Strain fidelity of chronic wasting disease upon murine adaptation. (2006)
Sigurdson, C J, Manco, G J, Schwarz, P, Liberski, P, Hoover, E A, Hornemann, S, ...
Chronic wasting disease (CWD), a prion disease of deer and elk, is highly prevalent in some regions of North America. The establishment of mouse-adapted CWD prions has proven difficult due to the...
PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer (2002)
Sigurdson, C.J., Barillas-Mury, C., Miller, M.W., Oesch, B., Langeveld, J.P.M., ...
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic...
Brojatsch, J, Kristal, B S, Viglianti, G A, Khiroya, R, Hoover, E A, Mullins, J I
Feline leukemia viruses (FeLVs) belonging to the C subgroup induce aplastic anemia in domestic cats and have the ability, unique among FeLV strains, to proliferate in guinea pig fibroblasts in tissue...
Zeidner, N S, Myles, M H, Mathiason-DuBard, C K, Dreitz, M J, Mullins, J I, Hoover, E A
The therapeutic efficacies of human recombinant alpha interferon (IFN-alpha), IFN-alpha plus zidovudine (AZT), and AZT alone were evaluated in presymptomatic cats with established feline leukemia...
Diehl, L J, Mathiason-DuBard, C K, O'Neil, L L, Hoover, E A
Cats infected with feline immunodeficiency virus (FIV) develop a disease syndrome similar to that caused by human immunodeficiency virus type 1 (HIV-1) infection in humans. HIV-1 replication has been...
Induction of accelerated feline immunodeficiency virus disease by acute-phase virus passage.
Diehl, L J, Mathiason-Dubard, C K, O'Neil, L L, Obert, L A, Hoover, E A
Development of feline immunodeficiency virus (FIV) infection in cats as a small animal model for lentiviral immunodeficiency disease has been hampered by the prolonged and variable disease course...
Mossman, S P, Bex, F, Berglund, P, Arthos, J, O'Neil, S P, Riley, D, ...
Infection of pigtail macaques with SIVsmmPBj14, biological clone 3 (SIV-PBj14-bc13), produces an acute and usually fatal shock-like syndrome 7 to 14 days after infection. We used this simian...
Diehl, L J, Mathiason-Dubard, C K, O'Neil, L L, Hoover, E A
Viral RNA load has been shown to indicate disease stage and predict the rapidity of disease progression in human immunodeficiency virus type 1 (HIV-1)-infected individuals. We had previously...
Frequent perinatal transmission of feline immunodeficiency virus by chronically infected cats.
O'Neil, L L, Burkhard, M J, Hoover, E A
Vertical transmission of feline immunodeficiency virus (FIV) was studied in cats infected with either of two FIV clinical isolates (FIV-B-2542 or FIV-AB-2771) prior to breeding and conception. Queens...
Bachmann, M H, Mathiason-Dubard, C, Learn, G H, Rodrigo, A G, Sodora, D L, Mazzetti, P, ...
For the rapid genetic analysis of feline immunodeficiency virus (FIV), we developed a heteroduplex mobility assay (HMA) that utilizes a PCR-amplified fragment of the FIV envelope gene spanning the...
Sodora, D L, Shpaer, E G, Kitchell, B E, Dow, S W, Hoover, E A, Mullins, J I
Feline immunodeficiency virus (FIV) is a lentivirus associated with AIDS-like illnesses in cats. As such, FIV appears to be a feline analog of human immunodeficiency virus (HIV). A hallmark of HIV...
Rohn, J L, Linenberger, M L, Hoover, E A, Overbaugh, J
In order to study retroviral variation, selection, and viral correlates of in vivo pathogenicity, we documented the evolution of feline leukemia virus (FeLV) variants in cats that died with thymic...
Kristal, B S, Reinhart, T A, Hoover, E A, Mullins, J I
The functions of the surface glycoproteins (SU) of feline leukemia viruses (FeLVs) are of interest since these proteins mediate virus infection and interference and are critical determinants of...
Reinhart, T A, Ghosh, A K, Hoover, E A, Mullins, J I
Cell killing by cytopathic retroviruses is often associated with a delay or failure in the establishment of superinfection interference. Superinfection has been observed during T-cell killing and...
Identification of a putative receptor for subgroup A feline leukemia virus on feline T cells.
Ghosh, A K, Bachmann, M H, Hoover, E A, Mullins, J I
Retrovirus infection is initiated by the binding of virus envelope glycoprotein to a receptor molecule present on cell membranes. To characterize a receptor for feline leukemia virus (FeLV), we...
Poss, M L, Mullins, J I, Hoover, E A
The envelope glycoprotein (gp70) of a molecularly cloned, replication-defective feline leukemia virus (FeLV-FAIDS clone 61C) carries determinants for induction of fatal immunodeficiency disease,...
Poss, M L, Quackenbush, S L, Mullins, J I, Hoover, E A
FeLV-FAIDS, an immunodeficiency-inducing isolate of feline leukemia virus, is composed of a pathogenic but replication-defective genome (molecular clone 61C) and a replication-competent but...
Quackenbush, S L, Donahue, P R, Dean, G A, Myles, M H, Ackley, C D, Cooper, M D, ...
The FeLV-FAIDS strain of feline leukemia virus consistently induces fatal immunodeficiency. To investigate the immunopathogenesis and viral genetic determinants responsible for the induction of...
Donahue, P R, Quackenbush, S L, Gallo, M V, DeNoronha, C M, Overbaugh, J, Hoover, E A, ...
Within the fatal immunodeficiency disease-inducing strain of feline leukemia virus, FeLV-FAIDS, are viruses which range in pathogenicity from minimally (clone 61E is the prototype) to acutely...
Donahue, P R, Hoover, E A, Beltz, G A, Riedel, N, Hirsch, V M, Overbaugh, J, ...
We report the first complete nucleotide sequence (8,440 base pairs) of a biologically active feline leukemia virus (FeLV), designated FeLV-61E (or F6A), and the molecular cloning, biological...
Riedel, N, Hoover, E A, Gasper, P W, Nicolson, M O, Mullins, J I
We describe the molecular cloning of an anemogenic feline leukemia virus (FeLV), FeLV-C-Sarma, from the productively infected human rhabdomyosarcoma cell line RD(FeLV-C-S). Molecularly cloned...
Fontenot, J D, Hoover, E A, Elder, J H, Montelaro, R C
The general model for retrovirus transmembrane (TM) proteins proposed by Gallaher et al. (W. R. Gallaher, J. M. Ball, R. F. Garry, M. C. Griffin, and R. C. Montelaro, AIDS Res. Hum. Retroviruses...
Pathogenic and host range determinants of the feline aplastic anemia retrovirus.
Riedel, N, Hoover, E A, Dornsife, R E, Mullins, J I
Feline leukemia virus (FeLV) C-Sarma (or FSC) is a prototype of subgroup C FeLVs, which induce fatal aplastic anemia in outbred specific-pathogen-free (SPF) cats. FeLV C isolates also possess an...
Dean, G A, Groshek, P M, Mullins, J I, Hoover, E A
Feline leukemia viruses (FeLVs) belonging to interference subgroup C induce fatal anemia resembling human pure red cell aplasia (PRCA). Subgroup A FeLVs, although closely related genetically to FeLVs...
Induction of immunity to feline caliciviral disease.
Kahn, D E, Hoover, E A, Bittle, J L
Six specific-pathogen-free cats were exposed by aerosol to a feline calicivirus of low virulence (F-9 virus). Homotypic (anti-F-9) seroconversion occurred in all cats by postexposure day 14. The...
Hoover, E A, Schaller, J P, Mathes, L E, Olsen, R G
Antibodies against feline leukemia virus (FeLV) and the feline oncornavirus-associated cell membrane antigen (FOCMA) were transferred from pregnant cats to their suckling kittens. All of these...
In vitro interaction of alveolar macrophages and pneumocytes with feline respiratory viruses.
Langloss, J M, Hoover, E A, Kahn, D E, Kniazeef, A J
Feline alveolar macrophages and feline pneumocytes were inoculated in vitro with low multiplicities of either feline calicivirus or feline viral rhinotracheitis virus. Pneumocytes were permissive for...
Brojatsch, J, Kristal, B S, Viglianti, G A, Khiroya, R, Hoover, E A, Mullins, J I
Feline leukemia viruses (FeLVs) belonging to the C subgroup induce aplastic anemia in domestic cats and have the ability, unique among FeLV strains, to proliferate in guinea pig fibroblasts in tissue...
Zeidner, N S, Myles, M H, Mathiason-DuBard, C K, Dreitz, M J, Mullins, J I, Hoover, E A
The therapeutic efficacies of human recombinant alpha interferon (IFN-alpha), IFN-alpha plus zidovudine (AZT), and AZT alone were evaluated in presymptomatic cats with established feline leukemia...
Diehl, L J, Mathiason-DuBard, C K, O'Neil, L L, Hoover, E A
Cats infected with feline immunodeficiency virus (FIV) develop a disease syndrome similar to that caused by human immunodeficiency virus type 1 (HIV-1) infection in humans. HIV-1 replication has been...
Induction of accelerated feline immunodeficiency virus disease by acute-phase virus passage.
Diehl, L J, Mathiason-Dubard, C K, O'Neil, L L, Obert, L A, Hoover, E A
Development of feline immunodeficiency virus (FIV) infection in cats as a small animal model for lentiviral immunodeficiency disease has been hampered by the prolonged and variable disease course...
Mossman, S P, Bex, F, Berglund, P, Arthos, J, O'Neil, S P, Riley, D, ...
Infection of pigtail macaques with SIVsmmPBj14, biological clone 3 (SIV-PBj14-bc13), produces an acute and usually fatal shock-like syndrome 7 to 14 days after infection. We used this simian...
Diehl, L J, Mathiason-Dubard, C K, O'Neil, L L, Hoover, E A
Viral RNA load has been shown to indicate disease stage and predict the rapidity of disease progression in human immunodeficiency virus type 1 (HIV-1)-infected individuals. We had previously...
Frequent perinatal transmission of feline immunodeficiency virus by chronically infected cats.
O'Neil, L L, Burkhard, M J, Hoover, E A
Vertical transmission of feline immunodeficiency virus (FIV) was studied in cats infected with either of two FIV clinical isolates (FIV-B-2542 or FIV-AB-2771) prior to breeding and conception. Queens...
Bachmann, M H, Mathiason-Dubard, C, Learn, G H, Rodrigo, A G, Sodora, D L, Mazzetti, P, ...
For the rapid genetic analysis of feline immunodeficiency virus (FIV), we developed a heteroduplex mobility assay (HMA) that utilizes a PCR-amplified fragment of the FIV envelope gene spanning the...
Sodora, D L, Shpaer, E G, Kitchell, B E, Dow, S W, Hoover, E A, Mullins, J I
Feline immunodeficiency virus (FIV) is a lentivirus associated with AIDS-like illnesses in cats. As such, FIV appears to be a feline analog of human immunodeficiency virus (HIV). A hallmark of HIV...
Rohn, J L, Linenberger, M L, Hoover, E A, Overbaugh, J
In order to study retroviral variation, selection, and viral correlates of in vivo pathogenicity, we documented the evolution of feline leukemia virus (FeLV) variants in cats that died with thymic...
Kristal, B S, Reinhart, T A, Hoover, E A, Mullins, J I
The functions of the surface glycoproteins (SU) of feline leukemia viruses (FeLVs) are of interest since these proteins mediate virus infection and interference and are critical determinants of...
Reinhart, T A, Ghosh, A K, Hoover, E A, Mullins, J I
Cell killing by cytopathic retroviruses is often associated with a delay or failure in the establishment of superinfection interference. Superinfection has been observed during T-cell killing and...
Identification of a putative receptor for subgroup A feline leukemia virus on feline T cells.
Ghosh, A K, Bachmann, M H, Hoover, E A, Mullins, J I
Retrovirus infection is initiated by the binding of virus envelope glycoprotein to a receptor molecule present on cell membranes. To characterize a receptor for feline leukemia virus (FeLV), we...
Poss, M L, Mullins, J I, Hoover, E A
The envelope glycoprotein (gp70) of a molecularly cloned, replication-defective feline leukemia virus (FeLV-FAIDS clone 61C) carries determinants for induction of fatal immunodeficiency disease,...
Poss, M L, Quackenbush, S L, Mullins, J I, Hoover, E A
FeLV-FAIDS, an immunodeficiency-inducing isolate of feline leukemia virus, is composed of a pathogenic but replication-defective genome (molecular clone 61C) and a replication-competent but...
Quackenbush, S L, Donahue, P R, Dean, G A, Myles, M H, Ackley, C D, Cooper, M D, ...
The FeLV-FAIDS strain of feline leukemia virus consistently induces fatal immunodeficiency. To investigate the immunopathogenesis and viral genetic determinants responsible for the induction of...
Donahue, P R, Quackenbush, S L, Gallo, M V, DeNoronha, C M, Overbaugh, J, Hoover, E A, ...
Within the fatal immunodeficiency disease-inducing strain of feline leukemia virus, FeLV-FAIDS, are viruses which range in pathogenicity from minimally (clone 61E is the prototype) to acutely...
Donahue, P R, Hoover, E A, Beltz, G A, Riedel, N, Hirsch, V M, Overbaugh, J, ...
We report the first complete nucleotide sequence (8,440 base pairs) of a biologically active feline leukemia virus (FeLV), designated FeLV-61E (or F6A), and the molecular cloning, biological...
Riedel, N, Hoover, E A, Gasper, P W, Nicolson, M O, Mullins, J I
We describe the molecular cloning of an anemogenic feline leukemia virus (FeLV), FeLV-C-Sarma, from the productively infected human rhabdomyosarcoma cell line RD(FeLV-C-S). Molecularly cloned...
Fontenot, J D, Hoover, E A, Elder, J H, Montelaro, R C
The general model for retrovirus transmembrane (TM) proteins proposed by Gallaher et al. (W. R. Gallaher, J. M. Ball, R. F. Garry, M. C. Griffin, and R. C. Montelaro, AIDS Res. Hum. Retroviruses...
Pathogenic and host range determinants of the feline aplastic anemia retrovirus.
Riedel, N, Hoover, E A, Dornsife, R E, Mullins, J I
Feline leukemia virus (FeLV) C-Sarma (or FSC) is a prototype of subgroup C FeLVs, which induce fatal aplastic anemia in outbred specific-pathogen-free (SPF) cats. FeLV C isolates also possess an...
Dean, G A, Groshek, P M, Mullins, J I, Hoover, E A
Feline leukemia viruses (FeLVs) belonging to interference subgroup C induce fatal anemia resembling human pure red cell aplasia (PRCA). Subgroup A FeLVs, although closely related genetically to FeLVs...
Induction of immunity to feline caliciviral disease.
Kahn, D E, Hoover, E A, Bittle, J L
Six specific-pathogen-free cats were exposed by aerosol to a feline calicivirus of low virulence (F-9 virus). Homotypic (anti-F-9) seroconversion occurred in all cats by postexposure day 14. The...
Hoover, E A, Schaller, J P, Mathes, L E, Olsen, R G
Antibodies against feline leukemia virus (FeLV) and the feline oncornavirus-associated cell membrane antigen (FOCMA) were transferred from pregnant cats to their suckling kittens. All of these...
In vitro interaction of alveolar macrophages and pneumocytes with feline respiratory viruses.
Langloss, J M, Hoover, E A, Kahn, D E, Kniazeef, A J
Feline alveolar macrophages and feline pneumocytes were inoculated in vitro with low multiplicities of either feline calicivirus or feline viral rhinotracheitis virus. Pneumocytes were permissive for...
Animal model of human disease: leukemic lymphoma.
Olsen, R. G., Mathes, L. E., Hebebrand, L. C., Hoover, E. A., Nichols, W. S.
Diffuse alveolar damage in cats induced by nitrogen dioxide or feline calicivirus.
Langloss, J. M., Hoover, E. A., Kahn, D. E.
The ultrastructural morphogenesis of pulmonary lesions was studied in cats exposed to either aerosols of feline calicivirus (FCV) or high concentrations of NO2. Both directly injured alveolar lining...