Piccio, L., Rossi, B., Scarpini, E., Laudanna, C., Giagulli, C., Issekutz, A. C., ...
Lymphocyte recruitment into the brain is a critical event in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis. We developed a novel intravital microscopy model to...
Expression of chemokine receptors by lung T cells from normal and asthmatic subjects. (2001)
Campbell, J.J., Brightling, Christopher E., Symon, F.A., Qin, S., Murphy, K.E., Hodge, M., ...
Mebius, R E, Streeter, P R, Michie, S, Butcher, E C, Weissman, I L
IN adult mice, the dominant adhesion molecules involved in homing to lymph nodes are L-selectin homing receptors on lymphocytes and the peripheral lymph node addressins on specialized high...
Von Andrian, U H, Chambers, J D, McEvoy, L M, Bargatze, R F, Arfors, K E, Butcher, E C
The lectin homing receptor LECAM-1 (LAM-1, Leu8) and the beta 2 integrins, particularly Mac-1 (CD11b/CD18), participate in leukocyte-endothelial cell interactions in inflammation. LECAM-1 is rapidly...
Kishimoto, T K, Jutila, M A, Butcher, E C
Lymphocyte migration to lymphoid organs involves organ-specific homing receptors. The mouse peripheral lymph node homing receptor, defined by the MEL-14 monoclonal antibody (mAb), is a lectin-like...
Gallatin, W M, Wayner, E A, Hoffman, P A, St John, T, Butcher, E C, Carter, W G
We have identified extensive structural homology between one type of heterotypic adhesion receptor (HAR) involved in lymphocyte interactions with high endothelium in lymphoid organs and a...
Interferon-gamma regulates an antigen specific for endothelial cells involved in lymphocyte traffic.
Duijvestijn, A M, Schreiber, A B, Butcher, E C
One of the most striking examples of localized vascular differentiation is exhibited by specialized lymphoid organ venules that mediate the extravasation of circulating lymphocytes from the blood....
Quiding-Järbrink, M, Nordström, I, Granström, G, Kilander, A, Jertborn, M, Butcher, E C, ...
Expression of the adhesion molecules CD44, L-selectin (CD62L), and integrin alpha 4 beta 7 by antibody-secreting cells (ASC) was examined in human volunteers after oral, rectal, intranasal, or...
Rott, L S, Rosé, J R, Bass, D, Williams, M B, Greenberg, H B, Butcher, E C
The integrin alpha4beta7 mediates lymphocyte binding to mucosal addressin cell adhesion molecule-1, and its expression defines lymphocytes capable of trafficking through the intestines and the...
Mebius, R E, Streeter, P R, Michie, S, Butcher, E C, Weissman, I L
IN adult mice, the dominant adhesion molecules involved in homing to lymph nodes are L-selectin homing receptors on lymphocytes and the peripheral lymph node addressins on specialized high...
Von Andrian, U H, Chambers, J D, McEvoy, L M, Bargatze, R F, Arfors, K E, Butcher, E C
The lectin homing receptor LECAM-1 (LAM-1, Leu8) and the beta 2 integrins, particularly Mac-1 (CD11b/CD18), participate in leukocyte-endothelial cell interactions in inflammation. LECAM-1 is rapidly...
Kishimoto, T K, Jutila, M A, Butcher, E C
Lymphocyte migration to lymphoid organs involves organ-specific homing receptors. The mouse peripheral lymph node homing receptor, defined by the MEL-14 monoclonal antibody (mAb), is a lectin-like...
Gallatin, W M, Wayner, E A, Hoffman, P A, St John, T, Butcher, E C, Carter, W G
We have identified extensive structural homology between one type of heterotypic adhesion receptor (HAR) involved in lymphocyte interactions with high endothelium in lymphoid organs and a...
Interferon-gamma regulates an antigen specific for endothelial cells involved in lymphocyte traffic.
Duijvestijn, A M, Schreiber, A B, Butcher, E C
One of the most striking examples of localized vascular differentiation is exhibited by specialized lymphoid organ venules that mediate the extravasation of circulating lymphocytes from the blood....
Quiding-Järbrink, M, Nordström, I, Granström, G, Kilander, A, Jertborn, M, Butcher, E C, ...
Expression of the adhesion molecules CD44, L-selectin (CD62L), and integrin alpha 4 beta 7 by antibody-secreting cells (ASC) was examined in human volunteers after oral, rectal, intranasal, or...
Rott, L S, Rosé, J R, Bass, D, Williams, M B, Greenberg, H B, Butcher, E C
The integrin alpha4beta7 mediates lymphocyte binding to mucosal addressin cell adhesion molecule-1, and its expression defines lymphocytes capable of trafficking through the intestines and the...
O'Neill, J K, Butter, C, Baker, D, Gschmeissner, S E, Kraal, G, Butcher, E C, ...
The expression of adhesion molecules on central nervous system (CNS) endothelia was examined during chronic relapsing experimental allergic encephalomyelitis (CREAE) in the Biozzi AB/H mouse. Active...
Briskin, M., Winsor-Hines, D., Shyjan, A., Cochran, N., Bloom, S., Wilson, J., ...
Lymphocyte homing to normal tissues and recruitment to inflammatory tissue sites are controlled, in part, by the selective expression of chemokines, pro-inflammatory cytokines and mediators, and...
Berg, E. L., Mullowney, A. T., Andrew, D. P., Goldberg, J. E., Butcher, E. C.
Carbohydrate ligands for lymphocyte L-selectin are expressed on high endothelial venules (HEVs) in peripheral lymph nodes and sites of chronic inflammation and mediate the recruitment of lymphocytes...
Dolcetti, R., Giardini, R., Doglioni, C., Cariati, R., Pomponi, F., D'Orazi, C., ...
We have previously shown that the in vivo coordinated expression of individual alpha 4 and beta 7 integrin chains correlated with the leukemic potential displayed by cell lines derived from murine...
Steffen, B. J., Breier, G., Butcher, E. C., Schulz, M., Engelhardt, B.
The expression of cell adhesion molecules (CAMs) in the choroid plexus was studied in normal brain and during experimental autoimmune encephalomyelitis (EAE) in the SJL/J mouse during inflammation...
Michie, S. A., Streeter, P. R., Butcher, E. C., Rouse, R. V.
Before the development of thymic lymphoma, AKR mice undergo a striking lymphoid hyperplasia of the thymic medulla. We have previously shown that there is a marked increase in traffic of B and T...
Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen.
Kraal, G., Schornagel, K., Streeter, P. R., Holzmann, B., Butcher, E. C.
The MAdCAM-1 adhesion molecule is involved in lymphocyte homing into mucosal sites and is expressed on high endothelial venules of Peyer's patches and mesenteric lymph nodes. In the spleen, where...
Picker, L. J., Michie, S. A., Rott, L. S., Butcher, E. C.
It has been proposed that the skin is a functionally unique compartment of the immune system, although little direct evidence supporting this hypothesis has been presented. Here we show that...
Duijvestijn, A. M., Horst, E., Pals, S. T., Rouse, B. N., Steere, A. C., Picker, L. J., ...
Lymphocyte traffic into lymph nodes and into mucosa-associated lymphoid tissues is regulated by specialized postcapillary high endothelial venules (HEVs). The authors have produced a rat monoclonal...
Expression of lymphocyte homing receptor antigen in non-Hodgkin's lymphoma.
Picker, L. J., Medeiros, L. J., Weiss, L. M., Warnke, R. A., Butcher, E. C.
In man, lymphocyte binding to high endothelial venules (HEVs) involves specific 85-95 kd cell surface glycoprotein(s) recognized by the monoclonal antibodies Hermes-1 and Hermes-3. These putative...
Steffen, B. J., Butcher, E. C., Engelhardt, B.
We have investigated the expression of vascular adhesion molecules during the first stage of chronic inflammation in experimental autoimmune encephalomyelitis in the SJL/J mouse. Immunocytochemical...
Michie, S. A., Streeter, P. R., Bolt, P. A., Butcher, E. C., Picker, L. J.
The extravasation of blood-borne lymphocytes into organized lymphoid tissues and sites of chronic inflammation is directed in part by interactions of lymphocyte surface adhesion molecules, known as...
Warnock, R.A., Campbell, J.J., Dorf, M.E., Matsuzawa, A., McEvoy, L.M., Butcher, E.C.
Chemokines have been hypothesized to contribute to the selectivity of lymphocyte trafficking not only as chemoattractants, but also by triggering integrin-dependent sticking (arrest) of circulating...