Mspl polymorphism at the human Complement component C6 gene (C6) (1991)
Coto, E., Domínguez, O., Martínez-Naves, E., Setién, F., Gutiérrez, V., López-Larrea, C.
MspI polymorphism at the human complement component C6 gene (C6) (1991)
Coto, E, Dominguez, O, Martinez-Naves, E, Setien, F, Gutierrez, V, Lopez-Larrea, C
Sacl polymorphism at the human TCR delta chain constant region (TCRD) (1991)
Martinez-Naves, E., Coto, E., Urra, J.M., Setién, F., Lopez-Larrea, C.
TaqI polymorphism at the human complement component C9 gene (1990)
Coto, E, Dominguez, O, Martinez-Naves, E, Urra, JM, Gutierrez, V, Lopez-Larrea, C
TaqI polymorphism in the complement component C7 gene (1990)
Coto, E, Martinez-Naves, E, Dominguez, O, Urra, JM, Rodriguez, V, Lopez-Larrea, C
MspI polymorphism at the human Complement component C6 gene (C6)
Coto, E., Domínguez, O., Martínez-Naves, E., Setién, F., Gutiérrez, V., López-Larrea, C.
SacI polymorphism at the human TCR delta chain constant region (TCRD)
Martínez-Naves, E., Coto, E., Urra, J.M., Setién, F., Lopez-Larrea, C.
González, M V, Artímez, M L, Rodrigo, L, López-Larrea, C, Menéndez, M J, Alvarez, V, ...
AIMS: To study the loss of heterozygosity and the presence of mutations at the p53, p16/CDKN2, and APC genes in Barrett's oesophagus, low grade dysplastic oesophageal epithelium, and adenocarcinoma...
González, M V, Pello, M F, López-Larrea, C, Suárez, C, Menéndez, M J, Coto, E
AIMS: To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to...
González, M V, Alvarez, V, Pello, M F, Menéndez, M J, Suárez, C, Coto, E
AIMS: To analyse the allele frequencies of DNA polymorphisms at the genes for cytochromes P450IIE1 and P450IID6, N-acetyltransferase-2, and glutathione S-transferase-M1 in patients with head and neck...
González, M V, Pello, M F, Ablanedo, P, Suárez, C, Alvarez, V, Coto, E
AIMS: To study the loss of heterozygosity at the short arm of chromosome 3 in primary tumours from patients with squamous cell carcinoma of the head and neck; to determine whether the FHIT gene,...
A spectrum of mutations in the second gene for autosomal dominant polycystic kidney disease (PKD2).
Veldhuisen, B, Saris, J J, De Haij, S, Hayashi, T, Reynolds, D M, Mochizuki, T, ...
Recently the second gene for autosomal dominant polycystic kidney disease (ADPKD), located on chromosome 4q21-q22, has been cloned and characterized. The gene encodes an integral membrane protein,...
MspI polymorphism at the human Complement component C6 gene (C6)
Coto, E., Domínguez, O., Martínez-Naves, E., Setién, F., Gutiérrez, V., López-Larrea, C.
SacI polymorphism at the human TCR delta chain constant region (TCRD)
Martínez-Naves, E., Coto, E., Urra, J.M., Setién, F., Lopez-Larrea, C.
González, M V, Artímez, M L, Rodrigo, L, López-Larrea, C, Menéndez, M J, Alvarez, V, ...
AIMS: To study the loss of heterozygosity and the presence of mutations at the p53, p16/CDKN2, and APC genes in Barrett's oesophagus, low grade dysplastic oesophageal epithelium, and adenocarcinoma...
González, M V, Pello, M F, López-Larrea, C, Suárez, C, Menéndez, M J, Coto, E
AIMS: To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to...
González, M V, Alvarez, V, Pello, M F, Menéndez, M J, Suárez, C, Coto, E
AIMS: To analyse the allele frequencies of DNA polymorphisms at the genes for cytochromes P450IIE1 and P450IID6, N-acetyltransferase-2, and glutathione S-transferase-M1 in patients with head and neck...
González, M V, Pello, M F, Ablanedo, P, Suárez, C, Alvarez, V, Coto, E
AIMS: To study the loss of heterozygosity at the short arm of chromosome 3 in primary tumours from patients with squamous cell carcinoma of the head and neck; to determine whether the FHIT gene,...
A spectrum of mutations in the second gene for autosomal dominant polycystic kidney disease (PKD2).
Veldhuisen, B, Saris, J J, De Haij, S, Hayashi, T, Reynolds, D M, Mochizuki, T, ...
Recently the second gene for autosomal dominant polycystic kidney disease (ADPKD), located on chromosome 4q21-q22, has been cloned and characterized. The gene encodes an integral membrane protein,...
HLA antigens in psoriatic arthritis subtypes of a Spanish population.
López-Larrea, C, Torre Alonso, J C, Rodriguez Perez, A, Coto, E
HLA-A, B, and C antigens were studied in 104 Spanish patients with psoriatic arthritis. Different clinical features were evaluated and the patients divided into disease subsets. HLA-B17, B27, B16,...
HLA antigens in multiple sclerosis of northern Spanish population.
López-Larrea, C, Uría, D F, Coto, E
HLA-A, -B, -C, -DR, -DQ antigens were studied in 43 multiple sclerosis (MS) patients with clinically definite remittent sclerosis from Asturias (North Spain). The prevalence of HLA-B7, B7 and B27...
Genetic and clinical studies in autosomal dominant polycystic kidney disease type 1 (ADPKD1).
Coto, E, Aguado, S, Alvarez, J, Menéndez Díaz, M J, López-Larrea, C
Thirteen Spanish families with autosomal dominant polycystic kidney disease were studied. In one family the disease did not segregate with polymorphic markers around the PKD1 locus. All subjects over...
Coto, E, Aguado, S, Alvarez, J, Arias, M, Menéndez, M J, ...
We studied 17 large families affected by adult dominant polycystic kidney disease (ADPKD). Ultrasonographic analysis was performed on all the family members. DNA microsatellite markers closely linked...
Ariza, M, Alvarez, V, Marín, R, Aguado, S, López-Larrea, C, Alvarez, J, ...
Autosomal dominant polycystic kidney disease (ADPKD) is a genetically heterogeneous disease. Most families show positive linkage to polymorphic markers around the PKD1 (16p13.3) or PKD2 (4q21-23)...
Alvarez, R., Alvarez, V., Lahoz, C., Martinez, C., Pena, J., Sanchez, J., ...
OBJECTIVES—Several lines of evidence suggest that the endothelial constitutive nitric oxide synthase (ecNOS) and angiotensin converting enzyme (ACE) may have a role in Alzheimer's disease. ACE is...