Schuetz, E G, Schinkel, A H, Relling, M V, Schuetz, J D
The P-glycoprotein (Pgp) efflux pump can influence the hepatocellular concentration of xenobiotics that are modulators and substrates of cytochrome P4503A (CYP3A). We tested the hypothesis that Pgp...
Burger, H J, Schuetz, J D, Schuetz, E G, Guzelian, P S
The family 3A cytochromes P-450, among the most abundant members of this supergene family of microsomal hemoproteins expressed in animal and human liver, are inducible by glucocorticoids but also by...
Guzelian, P S, Li, D, Schuetz, E G, Thomas, P, Levin, W, Mode, A, ...
Results of studies of hypophysectomized rats suggest that growth hormone serves as a final common mediator through which gonadal steroids and other modifiers of pituitary function alter the...
Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver.
Molowa, D T, Schuetz, E G, Wrighton, S A, Watkins, P B, Kremers, P, Mendez-Picon, G, ...
HLp is a human liver cytochrome P-450 that is immunochemically related to the glucocorticoid-inducible liver cytochrome P-450p in the rat and its homologue in the rabbit, P-450 LM3c. To investigate...
Identification of an inducible form of cytochrome P-450 in human liver.
Watkins, P B, Wrighton, S A, Maurel, P, Schuetz, E G, Mendez-Picon, G, Parker, G A, ...
It has not yet been determined whether human liver contains inducible cytochromes P-450 similar to those that catalyze the oxidative metabolism of foreign substances in animals. We carried out...
Watkins, P B, Wrighton, S A, Schuetz, E G, Molowa, D T, Guzelian, P S
We used monoclonal antibodies and complementary DNAs (cDNAs) to glucocorticoid-inducible liver cytochromes P-450 in rats (P-450p) and in man (HLp) to search for related cytochromes in intestinal...
Schuetz, E G, Schinkel, A H, Relling, M V, Schuetz, J D
The P-glycoprotein (Pgp) efflux pump can influence the hepatocellular concentration of xenobiotics that are modulators and substrates of cytochrome P4503A (CYP3A). We tested the hypothesis that Pgp...
Burger, H J, Schuetz, J D, Schuetz, E G, Guzelian, P S
The family 3A cytochromes P-450, among the most abundant members of this supergene family of microsomal hemoproteins expressed in animal and human liver, are inducible by glucocorticoids but also by...
Guzelian, P S, Li, D, Schuetz, E G, Thomas, P, Levin, W, Mode, A, ...
Results of studies of hypophysectomized rats suggest that growth hormone serves as a final common mediator through which gonadal steroids and other modifiers of pituitary function alter the...
Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver.
Molowa, D T, Schuetz, E G, Wrighton, S A, Watkins, P B, Kremers, P, Mendez-Picon, G, ...
HLp is a human liver cytochrome P-450 that is immunochemically related to the glucocorticoid-inducible liver cytochrome P-450p in the rat and its homologue in the rabbit, P-450 LM3c. To investigate...
Identification of an inducible form of cytochrome P-450 in human liver.
Watkins, P B, Wrighton, S A, Maurel, P, Schuetz, E G, Mendez-Picon, G, Parker, G A, ...
It has not yet been determined whether human liver contains inducible cytochromes P-450 similar to those that catalyze the oxidative metabolism of foreign substances in animals. We carried out...
Watkins, P B, Wrighton, S A, Schuetz, E G, Molowa, D T, Guzelian, P S
We used monoclonal antibodies and complementary DNAs (cDNAs) to glucocorticoid-inducible liver cytochromes P-450 in rats (P-450p) and in man (HLp) to search for related cytochromes in intestinal...