E. Gradelski

In vitro activity of BMS-181139, a new carbapenem with potent antipseudomonal activity.

Kessler, R E, Fung-Tomc, J, Kolek, B, Minassian, B, Huczko, E, Gradelski, E, ...

The in vitro activities of the carbapenem BMS-181139 were determined in comparison with those of imipenem, meropenem, ciprofloxacin, ceftriaxone, and vancomycin. BMS-181139 was the most active...

Activity of carbapenem BMS-181139 against Pseudomonas aeruginosa is not dependent on porin protein D2.

Fung-Tomc, J C, Gradelski, E, Kolek, B, Minassian, B, Pucci, M, Kessler, R E, ...

The broad antipseudomonal spectrum of the carbapenem BMS-181139 includes clinical strains and laboratory mutants of Pseudomonas aeruginosa that are resistant to imipenem. Unlike other known...

Structure-activity relationships of carbapenems that determine their dependence on porin protein D2 for activity against Pseudomonas aeruginosa.

Fung-Tomc, J C, Huczko, E, Banville, J, Ménard, M, Kolek, B, Gradelski, E, ...

A number of carbapenem derivatives were examined to determine the structure-activity relationships required for dependence on porin protein D2 for activity against Pseudomonas aeruginosa. As...

Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins.

Fung-Tomc, J C, Gradelski, E, Huczko, E, Dougherty, T J, Kessler, R E, Bonner, D P

The rates of development of resistance to ceftriaxone, ceftazidime, cefepime, and cefpirome in 10 strains of Enterobacter cloacae were determined by daily transfer for 7 days to fresh medium...

Antibacterial activity of BMS-180680, a new catechol-containing monobactam.

Fung-Tomc, J, Bush, K, Minassian, B, Kolek, B, Flamm, R, Gradelski, E, ...

The in vitro activities of a new catechol-containing monobactam, BMS-180680 (SQ 84,100), were compared to those of aztreonam, ceftazidime, imipenem, piperacillin-tazobactam, ciprofloxacin, amikacin,...

Emergence of homogeneously methicillin-resistant Staphylococcus aureus.

Fung-Tomc, J, Huczko, E, Gradelski, E, Denbleyker, K, Bonner, D P, Kessler, R E

Forty-seven clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA), collected between 1986 and 1990 from 29 institutions, were analyzed for susceptibility to various antibiotics....

In vitro activity of BMS-181139, a new carbapenem with potent antipseudomonal activity.

Kessler, R E, Fung-Tomc, J, Kolek, B, Minassian, B, Huczko, E, Gradelski, E, ...

The in vitro activities of the carbapenem BMS-181139 were determined in comparison with those of imipenem, meropenem, ciprofloxacin, ceftriaxone, and vancomycin. BMS-181139 was the most active...

Activity of carbapenem BMS-181139 against Pseudomonas aeruginosa is not dependent on porin protein D2.

Fung-Tomc, J C, Gradelski, E, Kolek, B, Minassian, B, Pucci, M, Kessler, R E, ...

The broad antipseudomonal spectrum of the carbapenem BMS-181139 includes clinical strains and laboratory mutants of Pseudomonas aeruginosa that are resistant to imipenem. Unlike other known...

Structure-activity relationships of carbapenems that determine their dependence on porin protein D2 for activity against Pseudomonas aeruginosa.

Fung-Tomc, J C, Huczko, E, Banville, J, Ménard, M, Kolek, B, Gradelski, E, ...

A number of carbapenem derivatives were examined to determine the structure-activity relationships required for dependence on porin protein D2 for activity against Pseudomonas aeruginosa. As...

Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins.

Fung-Tomc, J C, Gradelski, E, Huczko, E, Dougherty, T J, Kessler, R E, Bonner, D P

The rates of development of resistance to ceftriaxone, ceftazidime, cefepime, and cefpirome in 10 strains of Enterobacter cloacae were determined by daily transfer for 7 days to fresh medium...

Antibacterial activity of BMS-180680, a new catechol-containing monobactam.

Fung-Tomc, J, Bush, K, Minassian, B, Kolek, B, Flamm, R, Gradelski, E, ...

The in vitro activities of a new catechol-containing monobactam, BMS-180680 (SQ 84,100), were compared to those of aztreonam, ceftazidime, imipenem, piperacillin-tazobactam, ciprofloxacin, amikacin,...

Emergence of homogeneously methicillin-resistant Staphylococcus aureus.

Fung-Tomc, J, Huczko, E, Gradelski, E, Denbleyker, K, Bonner, D P, Kessler, R E

Forty-seven clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA), collected between 1986 and 1990 from 29 institutions, were analyzed for susceptibility to various antibiotics....