During the course of our work, mono-, and bis-sugar oximes as well as glycosylated carbamates were synthesized, analyzed by various spectroscopic techniques and evaluated pharmacologically. We found...
Shirvan, M H, Pollard, H B, Heldman, E
Acetylcholine evokes release from cultured bovine chromaffin cells by a mechanism that is believed to be classically nicotinic. However, we found that the full muscarinic agonist oxotremorine-M...
Endothelial cells from bovine adrenal medulla develop capillary-like growth patterns in culture.
Banerjee, D K, Ornberg, R L, Youdim, M B, Heldman, E, Pollard, H B
The endocrine barrier between chromaffin cells and the blood stream in the adrenal medulla is made of capillary endothelial cells. We have now succeeded in isolating endothelial cells from adrenal...
Calcium-mediated decrease of a voltage-dependent potassium current.
Alkon, D L, Shoukimas, J J, Heldman, E
Elevated intracellular Ca++ concentration reduces the amplitude of an early, voltage-dependent K+ current (IA) in the Type B photoreceptor of Hermissenda crassicornis. Internal Ca++ is increased by...
Sakakibara, M, Alkon, D L, DeLorenzo, R, Goldenring, J R, Neary, J T, Heldman, E
Iontophoretic injection of Ca2+ causes reduction of I0A (an early rapidly activating and inactivating K+ current) and I0C (a late Ca2+-dependent K+ current) measured across the isolated type B soma...
Inositol trisphosphate regulation of photoreceptor membrane currents.
Sakakibara, M, Alkon, D L, Neary, J T, Heldman, E, Gould, R
In previous studies elevation of intracellular Ca2+ was shown to cause prolonged reduction of two voltage-dependent K+ currents (IA and ICa2+-K+) across the membrane of the isolated Hermissenda...
Shirvan, M H, Pollard, H B, Heldman, E
Acetylcholine evokes release from cultured bovine chromaffin cells by a mechanism that is believed to be classically nicotinic. However, we found that the full muscarinic agonist oxotremorine-M...
Endothelial cells from bovine adrenal medulla develop capillary-like growth patterns in culture.
Banerjee, D K, Ornberg, R L, Youdim, M B, Heldman, E, Pollard, H B
The endocrine barrier between chromaffin cells and the blood stream in the adrenal medulla is made of capillary endothelial cells. We have now succeeded in isolating endothelial cells from adrenal...
Calcium-mediated decrease of a voltage-dependent potassium current.
Alkon, D L, Shoukimas, J J, Heldman, E
Elevated intracellular Ca++ concentration reduces the amplitude of an early, voltage-dependent K+ current (IA) in the Type B photoreceptor of Hermissenda crassicornis. Internal Ca++ is increased by...
Sakakibara, M, Alkon, D L, DeLorenzo, R, Goldenring, J R, Neary, J T, Heldman, E
Iontophoretic injection of Ca2+ causes reduction of I0A (an early rapidly activating and inactivating K+ current) and I0C (a late Ca2+-dependent K+ current) measured across the isolated type B soma...
Inositol trisphosphate regulation of photoreceptor membrane currents.
Sakakibara, M, Alkon, D L, Neary, J T, Heldman, E, Gould, R
In previous studies elevation of intracellular Ca2+ was shown to cause prolonged reduction of two voltage-dependent K+ currents (IA and ICa2+-K+) across the membrane of the isolated Hermissenda...