E. J. C. Goldstein

Two decades of imipenem therapy (2006)

Rodloff, A. C., Goldstein, E. J. C., Torres, A.

Imipenem, the first carbapenem discovered, was developed more than two decades ago in response to an unmet need for a highly potent, broad-spectrum antimicrobial agent with a strong safety profile....

Two decades of imipenem therapy (2006)

Rodloff, A. C., Goldstein, E. J. C., Torres, A.

Imipenem, the first carbapenem discovered, was developed more than two decades ago in response to an unmet need for a highly potent, broad-spectrum antimicrobial agent with a strong safety profile....

Characterization of a {beta}-lactamase from Clostridium clostridioforme (1994)

Appelbaum, P. C., Spangler, S. K., Pankuch, G. A., Philippon, A., Jacobs, M. R., Shiman, R., ...

A β-lactamase-producing strain of Clostridium clostridioforme isolated from human peritoneal fluid was examined by MIC testing and enzyme characterization. MICs of penicillins (64–512 mg/L)...

Characterization of Bacteroides forsythus Strains from Cat and Dog Bite Wounds in Humans and Comparison with Monkey and Human Oral Strains

Hudspeth, M. K., Gerardo, S. Hunt, Maiden, M. F. J., Citron, D. M., Goldstein, E. J. C.

Bacteroides forsythus strains recovered from cat and dog bite wound infections in humans (n = 3), monkey oral strains (n = 3), and the human oral ATCC 43037 type strain were characterized by using...

Characterization of Bacteroides forsythus Strains from Cat and Dog Bite Wounds in Humans and Comparison with Monkey and Human Oral Strains

Hudspeth, M. K., Gerardo, S. Hunt, Maiden, M. F. J., Citron, D. M., Goldstein, E. J. C.

In Vitro Activities of Ramoplanin, Teicoplanin, Vancomycin, Linezolid, Bacitracin, and Four Other Antimicrobials against Intestinal Anaerobic Bacteria

Citron, D. M., Merriam, C. V., Tyrrell, K. L., Warren, Y. A., Fernandez, H., Goldstein, E. J. C.

By using an agar dilution method, the in vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, and five other agents were determined against 300 gram-positive and 54 gram-negative...

Characterization of Bacteroides forsythus Strains from Cat and Dog Bite Wounds in Humans and Comparison with Monkey and Human Oral Strains

Hudspeth, M. K., Gerardo, S. Hunt, Maiden, M. F. J., Citron, D. M., Goldstein, E. J. C.

Bacteroides forsythus strains recovered from cat and dog bite wound infections in humans (n = 3), monkey oral strains (n = 3), and the human oral ATCC 43037 type strain were characterized by using...

Characterization of Bacteroides forsythus Strains from Cat and Dog Bite Wounds in Humans and Comparison with Monkey and Human Oral Strains

Hudspeth, M. K., Gerardo, S. Hunt, Maiden, M. F. J., Citron, D. M., Goldstein, E. J. C.

In Vitro Activities of Ramoplanin, Teicoplanin, Vancomycin, Linezolid, Bacitracin, and Four Other Antimicrobials against Intestinal Anaerobic Bacteria

Citron, D. M., Merriam, C. V., Tyrrell, K. L., Warren, Y. A., Fernandez, H., Goldstein, E. J. C.

By using an agar dilution method, the in vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, and five other agents were determined against 300 gram-positive and 54 gram-negative...

National Survey on the Susceptibility of Bacteroides fragilis Group: Report and Analysis of Trends in the United States from 1997 to 2004▿

Snydman, D. R., Jacobus, N. V., McDermott, L. A., Ruthazer, R., Golan, Y., Goldstein, E. J. C., ...

The susceptibility trends for the species of the Bacteroides fragilis group against various antibiotics from 1997 to 2004 were determined by using data for 5,225 isolates referred by 10 medical...

Clinical Outcomes, Safety, and Pharmacokinetics of OPT-80 in a Phase 2 Trial with Patients with Clostridium difficile Infection▿

Louie, T., Miller, M., Donskey, C., Mullane, K., Goldstein, E. J. C.

OPT-80, a novel, minimally absorbed macrocycle, is a candidate treatment option for Clostridium difficile infection (CDI) based on cure without recurrence of CDI in the hamster challenge model, good...