Dubelaar, E.J.G., Mufson, E.J., Meulen, W.G. Ter, Heerikhuize, J.J. Van, Verwer, R.W.H., Swaab, D.F.
In this study, we examined the metabolic activity of nucleus basalis of Meynert (NBM) neurons in individuals clinically diagnosed with no cognitive impairment (NCI, n = 8), mild cognitive impairment...
Gazzaley, A H, Siegel, S J, Kordower, J H, Mufson, E J, Morrison, J H
Age-associated memory impairment occurs frequently in primates. Based on the established importance of both the perforant path and N-methyl-D-aspartate (NMDA) receptors in memory formation, we...
Kordower, J H, Winn, S R, Liu, Y T, Mufson, E J, Sladek, J R, Hammang, J P, ...
Six Rhesus monkeys between 24 and 29 years of age received unilateral transections of the fornix. Three monkeys then received intraventricular transplants of polymer-encapsulated baby hamster kidney...
Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease.
Using a monoclonal antibody directed against the primate nerve growth factor (NGF) receptor, we examined the expression of NGF receptors within neuronal perikarya of normal adult human cerebral...
Gazzaley, A H, Siegel, S J, Kordower, J H, Mufson, E J, Morrison, J H
Age-associated memory impairment occurs frequently in primates. Based on the established importance of both the perforant path and N-methyl-D-aspartate (NMDA) receptors in memory formation, we...
Kordower, J H, Winn, S R, Liu, Y T, Mufson, E J, Sladek, J R, Hammang, J P, ...
Six Rhesus monkeys between 24 and 29 years of age received unilateral transections of the fornix. Three monkeys then received intraventricular transplants of polymer-encapsulated baby hamster kidney...
Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease.
Using a monoclonal antibody directed against the primate nerve growth factor (NGF) receptor, we examined the expression of NGF receptors within neuronal perikarya of normal adult human cerebral...
Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration
Cicchetti, F., Saporta, S., Hauser, R. A., Parent, M., Saint-Pierre, M., Sanberg, P. R., ...
The clinical evaluation of neural transplantation as a potential treatment for Huntington's disease (HD) was initiated in an attempt to replace lost neurons and improve patient outcomes. Two of 3...