E. Joan Blanchette-Mackie

Publication List Details

Period

2009 - 2009

Number

16

Co-Authors

Transduction of rat pancreatic islets with pseudotyped adeno-associated virus vectors (2009)

Craig, Anthony T, Gavrilova, Oksana, Dwyer, Nancy K, Jou, William, Pack, Stephanie, Liu, Eric, ...

Abstract Background Pancreatic islet transplantation is a promising treatment for type I diabetes mellitus, but current immunosuppressive strategies do not consistently provide long-term survival of...

Niemann-Pick C1 protein: Obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization

Watari, Hidemichi, Blanchette-Mackie, E. Joan, Dwyer, Nancy K., Glick, Jane M., Patel, Shutish, Neufeld, Edward B., ...

Niemann-Pick type C (NPC) disease is an inherited lipid storage disorder that affects the viscera and central nervous system. A characteristic feature of NPC cells is the lysosomal accumulation of...

Localization of Niemann–Pick C1 protein in astrocytes: Implications for neuronal degeneration in Niemann– Pick type C disease

Patel, Shutish C., Suresh, Sundar, Kumar, Ujendra, Hu, C. Y., Cooney, Adele, Blanchette-Mackie, E. Joan, ...

Niemann–Pick type C disease (NP-C) is an inherited neurovisceral lipid storage disorder characterized by progressive neurodegeneration. Most cases of NP-C result from inactivating mutations of...

Constitutive achlorhydria in mucolipidosis type IV

Schiffmann, Raphael, Dwyer, Nancy K., Lubensky, Irina A., Tsokos, Maria, Sutliff, Vincent E., Latimer, John S., ...

Mucolipidosis type IV is an autosomal recessive lysosomal storage disease of unknown etiology that causes severe neurological and ophthalmological abnormalities. In an attempt to obtain insight into...

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann–Pick type C1 disease

Zhang, Mei, Dwyer, Nancy K., Love, Dona C., Cooney, Adele, Comly, Marcy, Neufeld, Edward, ...

Niemann–Pick type C1 (NPC1) disease results from a defect in the NPC1 protein and is characterized by a pathological accumulation of cholesterol and glycolipids in endocytic organelles. We followed...

A Sperm-Associated WD Repeat Protein Orthologous to Chlamydomonas PF20 Associates with Spag6, the Mammalian Orthologue of Chlamydomonas PF16

Zhang, Zhibing, Sapiro, Rossana, Kapfhamer, David, Bucan, Maja, Bray, Jeff, Chennathukuzhi, Vargheese, ...

cDNAs were cloned for the murine and human orthologues of Chlamydomonas PF20, a component of the alga axoneme central apparatus that is required for flagellar motility. The mammalian genes encode...

Niemann-Pick C1 protein: Obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization

Watari, Hidemichi, Blanchette-Mackie, E. Joan, Dwyer, Nancy K., Glick, Jane M., Patel, Shutish, Neufeld, Edward B., ...

Niemann-Pick type C (NPC) disease is an inherited lipid storage disorder that affects the viscera and central nervous system. A characteristic feature of NPC cells is the lysosomal accumulation of...

Localization of Niemann–Pick C1 protein in astrocytes: Implications for neuronal degeneration in Niemann– Pick type C disease

Patel, Shutish C., Suresh, Sundar, Kumar, Ujendra, Hu, C. Y., Cooney, Adele, Blanchette-Mackie, E. Joan, ...

Niemann–Pick type C disease (NP-C) is an inherited neurovisceral lipid storage disorder characterized by progressive neurodegeneration. Most cases of NP-C result from inactivating mutations of...

Constitutive achlorhydria in mucolipidosis type IV

Schiffmann, Raphael, Dwyer, Nancy K., Lubensky, Irina A., Tsokos, Maria, Sutliff, Vincent E., Latimer, John S., ...

Mucolipidosis type IV is an autosomal recessive lysosomal storage disease of unknown etiology that causes severe neurological and ophthalmological abnormalities. In an attempt to obtain insight into...

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann–Pick type C1 disease

Zhang, Mei, Dwyer, Nancy K., Love, Dona C., Cooney, Adele, Comly, Marcy, Neufeld, Edward, ...

Niemann–Pick type C1 (NPC1) disease results from a defect in the NPC1 protein and is characterized by a pathological accumulation of cholesterol and glycolipids in endocytic organelles. We followed...

A Sperm-Associated WD Repeat Protein Orthologous to Chlamydomonas PF20 Associates with Spag6, the Mammalian Orthologue of Chlamydomonas PF16

Zhang, Zhibing, Sapiro, Rossana, Kapfhamer, David, Bucan, Maja, Bray, Jeff, Chennathukuzhi, Vargheese, ...

cDNAs were cloned for the murine and human orthologues of Chlamydomonas PF20, a component of the alga axoneme central apparatus that is required for flagellar motility. The mammalian genes encode...

Characterization of Two Unique Cholesterol-Rich Lipid Particles Isolated from Human Atherosclerotic Lesions

Chao, Fei-Fei, Blanchette-Mackie, E. Joan, Chen, Ya-Jun, Dickens, Benjamin F., Berlin, Elliott, Amende, Lynn M., ...

The authors' laboratory, using histochemicalmethods, previously identified two types of cholesterol-containing lipid particles in the extracellular spaces of human atherosclerotic lesions, one...

A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors.

Sun, Mei, Ma, Lanfeng, Xu, Linda, Li, Jia, Zhang, Wei, Petrovics, Gyorgy, ...

BACKGROUND: Deletion of chromosome 16q is frequently associated with diverse tumors. Numerous studies strongly suggest the presence of one or more tumor suppressor genes on chromosome 16q22 to 16qter...

SITES OF LIPOPROTEIN LIPASE ACTIVITY IN ADIPOSE TISSUE PERFUSED WITH CHYLOMICRONS : Electron Microscope Cytochemical Study

Blanchette-Mackie, E. Joan, Scow, Robert O.

Lipoprotein lipase activity was studied in rat parametrial adipose tissue perfused with chylomicrons and in gelatin blocks containing postheparin plasma and chylomicrons. The tissues and blocks were...

EFFECTS OF LIPOPROTEIN LIPASE ON THE STRUCTURE OF CHYLOMICRONS

Blanchette-Mackie, E. Joan, Scow, Robert O.

Chylomicrons isolated from rat lymph were complexed with lipoprotein lipase of post-heparin plasma (chylomicrons-LPL) in order to study the effects of lipolysis on the structure of chylomicrons....