E. L. Vitters

Species-specific expression of type II TGF-beta receptor isoforms by articular chondrocytes: effect of proteoglycan depletion and aging (1997)

Berg, W.B., Van Den, Vitters, E.L., Lafeber, F.P.J.G., Kraan, P.M., Van Der, Glansbeek, H.L.

Bone morphogenetic protein 2 stimulates articular cartilage proteoglycan synthesis in vivo but does not counteract Interleukin-1alpha effects on proteoglycan synthesis and content (1997)

Berg, W.B. Van Den, Kraan, P.M. Van Der, Morris, E.A., Vitters, E.L., Beuningen, H.M. Van, Glansbeek, H.L.

Early elevation of Transforming Growth Factor-Beta, decorin and biglycan mRNA levels during cartilage matrix restoration after mild proteoglycan depletion (1997)

Berg, W.B. Van Den, Vitters, E.L., Glansbeek, H.L., Kraan, P.M. Van Der

Maintenance of the synthesis of large proteoglycans in anatomically intact murine articular cartilage by steroids and insulin-like growth factor I.

Van Der Kraan, P M, Vitters, E L, Postma, N S, Verbunt, J, Van Den Berg, W B

OBJECTIVES--The exact regulation of the synthesis of cartilage specific molecules, such as collagen type II and aggrecan, by articular chondrocytes is unknown, but growth factors and hormones...

Correlation of the size of type II transforming growth factor beta (TGF-beta) receptor with TGF-beta responses of isolated bovine articular chondrocytes.

Glansbeek, H L, Van Der Kraan, P M, Vitters, E L, Van Den Berg, W B

OBJECTIVES--Transforming growth factor beta (TGF-beta) is a multipotent regulator of cell proliferation and extracellular matrix production. The effect of TGF-beta on chondrocyte matrix production...

Inhibition of proteoglycan synthesis by transforming growth factor beta in anatomically intact articular cartilage of murine patellae.

Van Der Kraan, P M, Vitters, E L, Van Den Berg, W B

The effect of transforming growth factor beta (TGF beta) on proteoglycan synthesis and degradation in anatomically intact articular cartilage of murine patellae was studied. Exogenously added TGF...

Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints.

Van Der Kraan, P. M., Vitters, E. L., Van De Putte, L. B., Van Den Berg, W. B.

Male, 10-week-old C57B1 10 mice received a single intraarticular injection in the knee joints with papain, iodoacetate, or collagenase. This led to osteoarthritic lesions, such as matrix depletion,...

Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage.

Lafeber, F. P., Van Der Kraan, P. M., Van Roy, H. L., Vitters, E. L., Huber-Bruning, O., Van Den Berg, W. B., ...

Proteoglycan synthesis of mild-to-moderate osteoarthritic human knee cartilage was compared with that of normal cartilage of the same donor. Immediately after cartilage was obtained, the synthesis...