Rahman, A., Reed, E., Underwood, M., Shipley, M. E., Omar, R. Z.
Objective. Chronic musculoskeletal pain is a very common and costly health problem. Patients presenting to rheumatology clinics with chronic pain can be difficult to manage. We studied 354 patients...
Assured Selection--- A Relaxed Concurrency Control Mechanism (2007)
Supervisor Esa Falkenroth, Nancy E. Reed, Examiner Nancy, E. Reed, Anders Trne, Anders Trne, ...
Le tecniche di mutua esclusione sono tradizionalmente applicate in ambienti a dati condivisi per evitare inconsistenze quando processi in esecuzione concorrente accedono simultaneamente alle risorse...
Moon, J.C.C., Reed, E., Sheppard, M.N., Elkington, A.G., Ho, S.Y., Burke, M., ...
Abstract: Objectives: We sought to identify the histologic basis of myocardial late gadolinium enhancement cardiovascular magnetic resonance (CMR) in hypertrophic cardiomyopathy (HCM). Background:...
Sandor, V., Reed, E., Sarosy, G., Middleton, L. P., Davis, P., Kohn, E.
Despite the known association of these malignancies, the incidence of a synchronous presentation of breast and ovarian cancer is low, and the current literature does not address an approach to this...
A phase I study of pentosan polysulfate sodium in patients with advanced malignancies (1996)
Lush, R. M., Figg, W. D., Pluda, J. M., Bitton, R., Headlee, D., Kohler, D., ...
Background: Pentosan polysulfate (xylanopolyhydrogensulfate) is a semi-synthetic sulfated heparinoid polysaccharide which has been used as an anticoagulant for nearly thirty years in Europe. It...
Gill, I., Muggia, F.M., Michael, C., Parker, R. J., Kortes, V., ...
Carboplatin and cisplatin have similar antitumor activities but different toxicities. Combining these two analogs may be expected to balance the toxicities and allow higher doses of platinum...
Kurane, I, Dai, L C, Livingston, P G, Reed, E, Ennis, F A
We previously reported that the clone JK34 was cross-reactive for dengue virus types 1, 2, 3, and 4 and recognized NS3 (I. Kurane, M. A. Brinton, A. L. Samson, and F. A. Ennis, J. Virol....
Dabholkar, M, Vionnet, J, Bostick-Bruton, F, Yu, J J, Reed, E
Nucleotide excision repair is a DNA repair pathway that is highly conserved in nature, with analogous repair systems described in Escherichia coli, yeast, and mammalian cells. The rate-limiting step,...
Reed, E, Ozols, R F, Tarone, R, Yuspa, S H, Poirier, M C
Fifty-five ovarian cancer patients receiving platinum drug-based chemotherapy have been studied prospectively to determine the extent of formation of the bidentate intrastrand adducts of...
Parker, R J, Eastman, A, Bostick-Bruton, F, Reed, E
Studies were undertaken to investigate acquired resistance to cisplatin in human ovarian cancer cells. The cell lines A2780 and A2780/CP70 were studied to assess their respective characteristics of...
Zhen, W, Link, C J, O'Connor, P M, Reed, E, Parker, R, Howell, S B, ...
We have studied several aspects of DNA damage formation and repair in human ovarian cancer cell lines which have become resistant to cisplatin through continued exposure to the anticancer drug. The...
Anti-idiotypic antibodies to anti-HLA receptors induced by pregnancy
Suciu-Foca, N., Reed, E., Rohowsky, C., Kung, P., King, D. W.
We have previously shown that lymphoblasts alloactivated in vitro acquire the capacity of stimulating the autologous mixed lymphocyte response. This response is anti-idiotypic in nature because...
Reed, E, Yuspa, S H, Zwelling, L A, Ozols, R F, Poirier, M C
The antitumor activity of cis-diamminedichloroplatinum II (cisplatin) is believed to be related to its covalent interaction with DNA where a major DNA binding product is an intrastrand N7-bidentate...
The docking protein p130(cas) (Crk-associated substrate) forms a stable complex with the adaptor protein CrkII in a tyrosine-phosphorylation-dependent manner. Insulin-induced tyrosine phosphorylation...
Immunomodulation of kidney and heart transplants by anti-idiotypic antibodies.
Hardy, M A, Suciu-Foca, N, Reed, E, Benvenisty, A I, Smith, C, Rose, E, ...
To explore the possibility that circulating HLA antigens from the graft and anti-anti-HLA (anti-idiotypic) antibodies influence the long-term survival of renal and cardiac allografts, analysis of 330...
Cisplatin-DNA damage and repair in peripheral blood leukocytes in vivo and in vitro.
Dabholkar, M, Bradshaw, L, Parker, R J, Gill, I, Bostick-Bruton, F, Muggia, F M, ...
We have extended our studies on the relationship between cisplatin/carboplatin-induced DNA damage in readily accessible tissue(s) and clinical response to therapy. Such an approach may assist in the...
Poirier, M C, Reed, E, Shamkhani, H, Tarone, R E, Gupta-Burt, S
Studies of platinum drug-DNA adduct formation in tissues of cancer patients have involved both atomic absorbance spectroscopy (AAS), which measures total DNA-bound platinum, and anti-cisplatin-DNA...
Poirier, M C, Reed, E, Zwelling, L A, Ozols, R F, Litterst, C L, Yuspa, S H
cis-Diamminedichloroplatinum (II) (cis-DDP), the antitumor drug, is cytotoxic in vitro primarily by binding to DNA and disrupting its normal functions. We have studied cis-DDP modification of DNA in...
Kurane, I, Dai, L C, Livingston, P G, Reed, E, Ennis, F A
We previously reported that the clone JK34 was cross-reactive for dengue virus types 1, 2, 3, and 4 and recognized NS3 (I. Kurane, M. A. Brinton, A. L. Samson, and F. A. Ennis, J. Virol....
Dabholkar, M, Vionnet, J, Bostick-Bruton, F, Yu, J J, Reed, E
Nucleotide excision repair is a DNA repair pathway that is highly conserved in nature, with analogous repair systems described in Escherichia coli, yeast, and mammalian cells. The rate-limiting step,...
Reed, E, Ozols, R F, Tarone, R, Yuspa, S H, Poirier, M C
Fifty-five ovarian cancer patients receiving platinum drug-based chemotherapy have been studied prospectively to determine the extent of formation of the bidentate intrastrand adducts of...
Parker, R J, Eastman, A, Bostick-Bruton, F, Reed, E
Studies were undertaken to investigate acquired resistance to cisplatin in human ovarian cancer cells. The cell lines A2780 and A2780/CP70 were studied to assess their respective characteristics of...
Zhen, W, Link, C J, O'Connor, P M, Reed, E, Parker, R, Howell, S B, ...
We have studied several aspects of DNA damage formation and repair in human ovarian cancer cell lines which have become resistant to cisplatin through continued exposure to the anticancer drug. The...
Anti-idiotypic antibodies to anti-HLA receptors induced by pregnancy
Suciu-Foca, N., Reed, E., Rohowsky, C., Kung, P., King, D. W.
We have previously shown that lymphoblasts alloactivated in vitro acquire the capacity of stimulating the autologous mixed lymphocyte response. This response is anti-idiotypic in nature because...
Reed, E, Yuspa, S H, Zwelling, L A, Ozols, R F, Poirier, M C
The antitumor activity of cis-diamminedichloroplatinum II (cisplatin) is believed to be related to its covalent interaction with DNA where a major DNA binding product is an intrastrand N7-bidentate...
The docking protein p130(cas) (Crk-associated substrate) forms a stable complex with the adaptor protein CrkII in a tyrosine-phosphorylation-dependent manner. Insulin-induced tyrosine phosphorylation...
Immunomodulation of kidney and heart transplants by anti-idiotypic antibodies.
Hardy, M A, Suciu-Foca, N, Reed, E, Benvenisty, A I, Smith, C, Rose, E, ...
To explore the possibility that circulating HLA antigens from the graft and anti-anti-HLA (anti-idiotypic) antibodies influence the long-term survival of renal and cardiac allografts, analysis of 330...
Cisplatin-DNA damage and repair in peripheral blood leukocytes in vivo and in vitro.
Dabholkar, M, Bradshaw, L, Parker, R J, Gill, I, Bostick-Bruton, F, Muggia, F M, ...
We have extended our studies on the relationship between cisplatin/carboplatin-induced DNA damage in readily accessible tissue(s) and clinical response to therapy. Such an approach may assist in the...
Poirier, M C, Reed, E, Shamkhani, H, Tarone, R E, Gupta-Burt, S
Studies of platinum drug-DNA adduct formation in tissues of cancer patients have involved both atomic absorbance spectroscopy (AAS), which measures total DNA-bound platinum, and anti-cisplatin-DNA...
Poirier, M C, Reed, E, Zwelling, L A, Ozols, R F, Litterst, C L, Yuspa, S H
cis-Diamminedichloroplatinum (II) (cis-DDP), the antitumor drug, is cytotoxic in vitro primarily by binding to DNA and disrupting its normal functions. We have studied cis-DDP modification of DNA in...
Chadburn, A., Suciu-Foca, N., Cesarman, E., Reed, E., Michler, R. E., Knowles, D. M.
Recent clinical, pathological, and molecular studies have increased our understanding of posttransplantation lymphoproliferative disorders (PT-LPDs). Studies have shown that the majority of PT-LPDs...
Measures of renal function in patients with cisplatin-related chronic renal disease.
Reed, E., Jacob, J., Brawley, O.
Twenty-seven patients with advanced stage refractory ovarian cancer were studied to determine if chronic stable cisplatin-related renal dysfunction was present. Medical histories were examined to...
Taxol dose intensification and its clinical implications.
Taxol is the most exciting new anticancer agent developed in the past two decades. Of great interest is its level of activity in ovarian cancer, as well as substantial activity in breast cancer,...
The use of colony-stimulating factors as bone marrow support for systemic anticancer chemotherapy.
Colony-stimulating factors (CSFs) are proteins that play normal roles in human hematopoietic physiology. Many of these factors have been cloned and sequences. This has led to recombinant DNA...
Bergan, R. C., Walls, R. G., Figg, W. D., Dawson, N. A., Headlee, D., Tompkins, A., ...
African-American males have a higher incidence of prostate cancer than non-African-American males and an overall poorer prognosis. Environmental factors such as socioeconomic status and biological...
A 'family clinic' for information exchange in an oncology unit.
Parker, D., Quinn, P., Eustace, P., Holford, P., Penny, E., Ryan, M., ...
Horti, J, Dixon, S C, Logothetis, C J, Guo, Y, Reed, E, Figg, W D
Prostate-specific antigen, PSA, is regarded as a reliable surrogate marker for androgen-independent prostate cancer (AIPC). Concern has been raised that investigational agents may affect PSA...