Glupczynski, Y, Blogie, M, Verbiest, N, Vandeven, J, ...
During the 13-year period from 1 November 1980 to 31 January 1993, we received and serotyped a total of 5,619 clinically significant strains of Streptococcus pneumoniae isolated in more than 75...
[Trends in pneumococcal infections in Belgium from 1986 to 1991] (1993)
Walckiers, D, Glupczynski, Y, Yourassowsky, E
Streptococcus pneumoniae is one of the most frequent causes of pneumonia, meningitis, and otitis media. Persons at high risk are young children, elderly, and individuals with immunodeficiency or with...
Guide to antimicrobial therapy 1992 (1992)
BOELAERT, J, CLUMECK, N, LAUWERS, S, LEVY, J, PIOT, P, VAN LANDUYT, H, ...
Glupczynski, Y, Blogie, M, Vandeven, J, Yourassowsky, E, ...
A total of 2,765 strains of Streptococcus pneumoniae isolated in more than 60 Belgian laboratories from blood or normally sterile body fluids between 1 November 1980 and 31 December 1988 were...
Antibacterial effect of meropenem and imipenem on Proteus mirabilis (1990)
Yourassowsky, E., Van Der Linden, M. P., Crokaert, F.
Phase-contrast microscopy, killing-curves and turbidimetric growth-curves were used in a comparative study of the antibacterial effects of a new carbapenem, meropenem (SM 7338) and imipenem on five...
Bactericidal activity of meropenem against Pseudomonas aeruginosa (1989)
Yourassowsky, E., Van Der Linden, M. P., Lismont, M. J., Crokaert, F., Glupczynski, Y.
Ten strains of Pseudomonas aeruginosa that were susceptible to imipenem (MICs 2 mg/1) were exposed to a new parenteral carbapenem, meropenem (MIC 025 mg/l). Kinetic turbidometry showed that, as with...
Effect of antibiotic carry-over on bacterial counting by 'spiral plating' (1988)
YOURASSOWSKY, E., VAN DER LINDEN, M. P., CROKAERT, F., GLUPCZYNSKI, Y.
Enoxacin in acute exacerbations of chronic bronchitis: a comparison with amoxycillin (1988)
Prigogine, T., Glupczynski, Y., Carpiaux, J. P., Blogie, M., Yourassowsky, E., Schmerber, J. S.
A total of 43 hospitalized adult patients with acute exacerbations of chronic bronchitis or bronchiectasis due to Gram-negative bacteria were randomized to receive either enoxacin (400 mg bd) or...
In-vitro activity of pefloxacin compared to other antibiotics (1986)
Yourassowsky, E., Van Der Linden, M. P., Crokaert, F., Glupczynski, Y.
Pefloxacin is a new quinolone carboxylic acid with a broad spectrum of antibacterial activity. A comparison was made of the in-vitro activity of pefloxacin and that of nine other antibiotics...
Yourassowsky, E., Van Der Linden, M. P., Lismont, M. J., Crokaert, F., Glupczynski, Y.
The effect of a brief β-lactam action on a bacteria] culture has been studied by combining the use of a high performance photometer with phase contrast microscopic examination. After exposure of the...
Susceptibility of anaerobic bacteria to Sch 34343 and other antibiotics (1985)
Glupczynski, Y., Gordts, B., Van Der Linden, M. P., Labbé, M., Yourassowsky, E., Butzler, J. P.
The in-vitro activity of Sch 34343 was evaluated against 137 strains of anaerobic bacteria by the agar dilution technique Sch 34343 was compared with imipenem, cefoxitin, latamoxef (moxalactam),...
Yourassowsky, E., Lismont, M.J., Crokaert, F.
The growth curve patterns of 8 strains of Escherichia coli exposed to amoxycillin or ampicillin were studied in the MS-2 system, which allows an accurate comparison over a widerange of...
Late prosthetic valve endocarditis: review of 19 cases and treatment (1983)
PRIGOGINE, TH., GOFFIN, Y., DEUVAERT, F., TELERMAN, M., PRIMO, G., YOURASSOWSKY, E.
Eighteen out of 1606 patients treated by valve replacement between January 1971 to June 1979 were admitted in Brugmann University Hospital for late prosthetic valve endocarditis. Of the 19 episodes...
International collaborative study on standardization of bacterial sensitivity to fosfomycin (1983)
Andrews, J. M., Baquero, F., Beltran, J. M., Canton, E., Crokaert, F., Gobernado, M., ...
An international collaborative study was undertaken involving 6 working groups to correlate the zone sizes obtained with 50 μg fosfomycin+25 μg glucose-6-phosphate (G6P) and 50 μg fosfomycin...
Yourassowsky, E., Van Der Linden, M. P., Lismont, M. J., Croaert, F.
β-Lactam antibiotics have different modes of action which may be reflected by different morphological modifications of bacteria. A relationship may be found between the growth curve pattern and the...
Yourassowsky, E., Van Der Linden, M. P., Lismont, M. J., Labbé, M., Crokaert, F.
The effect of different concentrations of β-lactam antibiotics on the growth curves of Bacteroides fragilis NTCC 9343 was studied in transfer cartridges in an Abbott MS-2 system. Anaerobic...
Yourassowsky, E., Schoutens, E., Vanderlinden, M. P.
Two hundred recent clinical isolates of Haemophilus and Pneumococcus were tested in vitro against eight cephalosporins by means of disc diffusion and agar dilution tests. In the case of Haemophilus,...
Yourassowsky, E, Van Der Linden, M P, Crokaert, F
Cephalosporins have been recommended as prophylactic antibiotics in patients undergoing cardiovascular surgery. The major function of these antibiotics is to protect patients against Staphylococcus...
In vitro susceptibility of Alcaligenes denitrificans subsp. xylosoxidans to 24 antimicrobial agents.
Glupczynski, Y, Hansen, W, Freney, J, Yourassowsky, E
The in vitro susceptibilities of 37 clinical isolates of Alcaligenes denitrificans subsp. xylosoxidans to 24 antimicrobial agents were determined. Imipenem was the only drug with consistent activity...
Yourassowsky, E, Van Der Linden, M P, Lismont, M J, Crokaert, F, Glupczynski, Y
Enterobacter cloacae infections have been shown clinically to respond less reliably to monotherapy with broad-spectrum cephalosporins than was initially expected. Selection of populations producing...
Yourassowsky, E, Van Der Linden, M P, Lismont, M J, Crokaert, F, Glupczynski, Y
Escherichia coli strains that were susceptible to multiple antibiotics were exposed to suprainhibitory concentrations of ampicillin and piperacillin. As with the majority of beta-lactam antibiotics,...
Glupczynski, Y, Lagast, H, Thys, J P, Crokaert, F, Yourassowsky, E, ...
Teicoplanin was evaluated in 47 patients with severe infections, including 14 patients with bone infections, 11 patients with soft-tissue infections, 7 patients with endocarditis, 5 patients with...
Yourassowsky, E, Van Der Linden, M P, Lismont, M J, Crokaert, F, Glupczynski, Y
The rate of bactericidal activity of a new quinolone, CI-934, was compared with that of amoxicillin for 20 strains of Streptococcus faecalis. At 10 and 100 micrograms/ml, the bactericidal activity of...
Activities of amoxicillin and clavulanic acid combinations against urinary tract infections.
Crokaert, F, Van Der Linden, M P, Yourassowsky, E
Urinary tract infection caused by beta-lactamase-producing bacteria were treated with 500 mg of amoxicillin three times daily plus either 250 or 125 mg of clavulanic acid three times daily. The...
Yourassowsky, E., Schoutens, E.
The quantitative study (counting and size and surface evaluation of bacterial colonies) of the activity of an antimicrobial agent against a microbial population growing in solid medium can be...
Yourassowsky, E, Van Der Linden, M P, Crokaert, F
The relationship between the growth rate and the kill rate was used to evaluate and to compare the in vitro bactericidal activities of cefdinir, a new oral cephalosporin, and cefaclor against...
Crokaert, F, Lismont, M J, Van Der Linden, M P, Yourassowsky, E
The resistance of gram-negative bacteria to complement-mediated serum activity is supposedly an important virulence factor. However, the lack of standardization in the methods used to determine serum...
Detection of Gardnerella vaginalis in vaginal specimens by direct immunofluorescence.
Hansen, W, Vray, B, Miller, K, Crokaert, F, Yourassowsky, E
The preparation of a fluorescein-labeled Gardnerella vaginalis polyclonal antibody is described, and its usefulness is assessed for the detection of this microorganism in vaginal samples obtained...
Glupczynski, Y, Labbé, M, Hansen, W, Crokaert, F, Yourassowsky, E
The Progressive Diagnostics Manufacturers epsilometer test (E test; AB Biodisk, Solna, Sweden), a quantitative variant of the disk diffusion technique, was evaluated comparatively to an agar dilution...
Flavobacterium multivorum septicemia in a hemodialyzed patient.
Potvliege, C, Dejaegher-Bauduin, C, Hansen, W, Dratwa, M, Collart, F, Tielemans, C, ...
A case of Flavobacterium multivorum septicemia in a hemodialyzed patient is reported. Two blood cultures were positive at 48 h, and the patient became afebrile only after antimicrobial therapy. The...
Four hundred strains of lactose-fermenting Enterobacteriaceae were tested for hydrolysis of p-nitrophenyl-beta-D-glucopyranosiduronic acid, the chromogenic enzyme substrate of beta-glucuronidase....
Pseudomonas paucimobilis peritonitis in patients treated by peritoneal dialysis.
Glupczynski, Y, Hansen, W, Dratwa, M, Tielemans, C, Wens, R, Collart, F, ...
Pseudomonas paucimobilis has rarely been reported as an opportunistic human pathogen. We report the isolation of this organism in two patients who developed peritonitis during the course of...
Two strains of Vibrio species with unusual biochemical features isolated from ear tracts.
Hansen, W, Crokaert, F, Yourassowsky, E
A strain of vibrio cholerae Heiberg type II, not agglutinable with any of the eight antisera corresponding to Heiberg's groups, and a nonmotile, methyl red-positivs of chronic external otitis.
Plasma beta 2 microglobulin as a means of predicting gentamicin serum concentrations.
Valsamis, J, Brauman, H, Yourassowsky, E
A novel and accurate method for predicting gentamicin peak serum concentration is described. The method considers body weight and renal function as determined by the concentration of beta 2...
Yourassowsky, E., Van Der Linden, M. P., Lismont, M. J., Crokaert, F.
The growth curves automatically recorded and printed during the action of 10 cephalosporins on methicillin-susceptible and methicillin-resistant Staphylococcus aureus showed the following. (i) The...
Amoxicillin Entry into Human Cerebrospinal Fluid: Comparison with Ampicillin
Clumeck, N., Thys, J. P., Vanhoof, R., Vanderlinden, M. P., Butzler, J. P., Yourassowsky, E.
The entry of amoxicillin and ampicillin into cerebrospinal fluid (CSF) of humans was studied in the absence of meningeal inflammation. Twelve volunteers received 33 mg of amoxicillin per kg...
Susceptibility of Campylobacter fetus subsp. jejuni to Twenty-Nine Antimicrobial Agents
Vanhoof, R., Vanderlinden, M. P., Dierickx, R., Lauwers, S., Yourassowsky, E., Butzler, J. P.
The activity of 29 antimicrobial agents was tested against 95 strains of Campylobacter fetus subsp. jejuni isolated from human stools. Furazolidone and gentamycin were the most active agents. The...
Yourassowsky, E., Lismont, M. J.
In contrast to the results obtained with ampicillin, the minimum inhibitory concentrations of cefamandole against Haemophilus influenzae were within the same range (0.5 to 1.5 μg/ml) whether or not...
Yourassowsky, E., Vanderlinden, M. P., Lismont, M. J., Schoutens, E.
The killing rate of a zonal concentration gradient of penicillin G on Staphylococcus aureus was studied by using a previously described triple-layer technique, enzymatic inactivation of the...
Speed of Bactericidal Action of Penicillin G, Ampicillin, and Carbenicillin on Bacteroides fragilis
Schoutens, E., Yourassowsky, E.
In order to determine the therapeutic value of penicillins in the management of anaerobic infections caused by Bacteroides fragilis, the antibacterial activity of penicillin G, ampicillin, and...
Sensitivity of Streptococcus pyogenes to sulphamethoxazole, trimethoprim, and cotrimoxazole
Yourassowsky, E., Vanderlinden, M. P., Schoutens, E.
When tested on Wellcotest (sensitivity test agar, Wellcome) supplemented with lysed horse blood, 59 clinical isolates of beta-haemolytic streptococci, belonging to several serological groups, are all...
Hansen, W, Schoutens, E, Yourassowsky, E
One hundred and twenty-two clinical isolates of Acinetobacter were studied for the presence of beta-galactosidase and of beta-xylosidase, for biochemical characteristics, and for genetic interspecies...
Yourassowsky, E, Van Der Linden, MP, Lismont, MJ, Crokaert, F
Methicillin- and gentamicin-resistant Staphylococcus aureus may remain sensitive to minocycline and to rifampicin. A study of growth curves has shown that at inhibitory concentrations (0·4 μg/ml),...
Yourassowsky, E, Van Der Linden, M P, Schoutens, E
When Haemophilus influenzae infections are treated by an antibiotic acting on the bacterial wall, the adequacy of antimicrobial therapy can be assessed by Schlichter's test. This test may be carried...
Hansen, W, Schoutens, E, Yourassowsky, E
A total of 314 strains of Haemophilus, isolated from clinical samples, were studied for the production of beta-galactosidase and beta-xylosidase. None of the H. influenzae strains studied (9...
Detection of Bacteroides fragilis and Bacteroides melaninogenicus by direct immunofluorescence.
Labbé, M, Delamare, N, Pepersack, F, Crokaert, F, Yourassowsky, E
A new diagnostic kit, which contains a polyvalent antiserum for either Bacteroides fragilis or Bacteroides melaninogenicus, was tested for reliability and specificity on 146 clinical samples of...
Yourassowsky, E, Van Der Linden, M P, Crokaert, F
Cephalosporins have been recommended as prophylactic antibiotics in patients undergoing cardiovascular surgery. The major function of these antibiotics is to protect patients against Staphylococcus...
In vitro susceptibility of Alcaligenes denitrificans subsp. xylosoxidans to 24 antimicrobial agents.
Glupczynski, Y, Hansen, W, Freney, J, Yourassowsky, E
The in vitro susceptibilities of 37 clinical isolates of Alcaligenes denitrificans subsp. xylosoxidans to 24 antimicrobial agents were determined. Imipenem was the only drug with consistent activity...
Yourassowsky, E, Van Der Linden, M P, Lismont, M J, Crokaert, F, Glupczynski, Y
Enterobacter cloacae infections have been shown clinically to respond less reliably to monotherapy with broad-spectrum cephalosporins than was initially expected. Selection of populations producing...
Yourassowsky, E, Van Der Linden, M P, Lismont, M J, Crokaert, F, Glupczynski, Y
Escherichia coli strains that were susceptible to multiple antibiotics were exposed to suprainhibitory concentrations of ampicillin and piperacillin. As with the majority of beta-lactam antibiotics,...
Glupczynski, Y, Lagast, H, Thys, J P, Crokaert, F, Yourassowsky, E, ...
Teicoplanin was evaluated in 47 patients with severe infections, including 14 patients with bone infections, 11 patients with soft-tissue infections, 7 patients with endocarditis, 5 patients with...
Yourassowsky, E, Van Der Linden, M P, Lismont, M J, Crokaert, F, Glupczynski, Y
The rate of bactericidal activity of a new quinolone, CI-934, was compared with that of amoxicillin for 20 strains of Streptococcus faecalis. At 10 and 100 micrograms/ml, the bactericidal activity of...
Activities of amoxicillin and clavulanic acid combinations against urinary tract infections.
Crokaert, F, Van Der Linden, M P, Yourassowsky, E
Urinary tract infection caused by beta-lactamase-producing bacteria were treated with 500 mg of amoxicillin three times daily plus either 250 or 125 mg of clavulanic acid three times daily. The...
Yourassowsky, E., Schoutens, E.
The quantitative study (counting and size and surface evaluation of bacterial colonies) of the activity of an antimicrobial agent against a microbial population growing in solid medium can be...
Yourassowsky, E, Van Der Linden, M P, Crokaert, F
The relationship between the growth rate and the kill rate was used to evaluate and to compare the in vitro bactericidal activities of cefdinir, a new oral cephalosporin, and cefaclor against...
Crokaert, F, Lismont, M J, Van Der Linden, M P, Yourassowsky, E
The resistance of gram-negative bacteria to complement-mediated serum activity is supposedly an important virulence factor. However, the lack of standardization in the methods used to determine serum...
Detection of Gardnerella vaginalis in vaginal specimens by direct immunofluorescence.
Hansen, W, Vray, B, Miller, K, Crokaert, F, Yourassowsky, E
The preparation of a fluorescein-labeled Gardnerella vaginalis polyclonal antibody is described, and its usefulness is assessed for the detection of this microorganism in vaginal samples obtained...
Glupczynski, Y, Labbé, M, Hansen, W, Crokaert, F, Yourassowsky, E
The Progressive Diagnostics Manufacturers epsilometer test (E test; AB Biodisk, Solna, Sweden), a quantitative variant of the disk diffusion technique, was evaluated comparatively to an agar dilution...
Flavobacterium multivorum septicemia in a hemodialyzed patient.
Potvliege, C, Dejaegher-Bauduin, C, Hansen, W, Dratwa, M, Collart, F, Tielemans, C, ...
A case of Flavobacterium multivorum septicemia in a hemodialyzed patient is reported. Two blood cultures were positive at 48 h, and the patient became afebrile only after antimicrobial therapy. The...
Four hundred strains of lactose-fermenting Enterobacteriaceae were tested for hydrolysis of p-nitrophenyl-beta-D-glucopyranosiduronic acid, the chromogenic enzyme substrate of beta-glucuronidase....
Pseudomonas paucimobilis peritonitis in patients treated by peritoneal dialysis.
Glupczynski, Y, Hansen, W, Dratwa, M, Tielemans, C, Wens, R, Collart, F, ...
Pseudomonas paucimobilis has rarely been reported as an opportunistic human pathogen. We report the isolation of this organism in two patients who developed peritonitis during the course of...
Two strains of Vibrio species with unusual biochemical features isolated from ear tracts.
Hansen, W, Crokaert, F, Yourassowsky, E
A strain of vibrio cholerae Heiberg type II, not agglutinable with any of the eight antisera corresponding to Heiberg's groups, and a nonmotile, methyl red-positivs of chronic external otitis.
Plasma beta 2 microglobulin as a means of predicting gentamicin serum concentrations.
Valsamis, J, Brauman, H, Yourassowsky, E
A novel and accurate method for predicting gentamicin peak serum concentration is described. The method considers body weight and renal function as determined by the concentration of beta 2...
Yourassowsky, E., Van Der Linden, M. P., Lismont, M. J., Crokaert, F.
The growth curves automatically recorded and printed during the action of 10 cephalosporins on methicillin-susceptible and methicillin-resistant Staphylococcus aureus showed the following. (i) The...
Amoxicillin Entry into Human Cerebrospinal Fluid: Comparison with Ampicillin
Clumeck, N., Thys, J. P., Vanhoof, R., Vanderlinden, M. P., Butzler, J. P., Yourassowsky, E.
The entry of amoxicillin and ampicillin into cerebrospinal fluid (CSF) of humans was studied in the absence of meningeal inflammation. Twelve volunteers received 33 mg of amoxicillin per kg...
Susceptibility of Campylobacter fetus subsp. jejuni to Twenty-Nine Antimicrobial Agents
Vanhoof, R., Vanderlinden, M. P., Dierickx, R., Lauwers, S., Yourassowsky, E., Butzler, J. P.
The activity of 29 antimicrobial agents was tested against 95 strains of Campylobacter fetus subsp. jejuni isolated from human stools. Furazolidone and gentamycin were the most active agents. The...
Yourassowsky, E., Lismont, M. J.
In contrast to the results obtained with ampicillin, the minimum inhibitory concentrations of cefamandole against Haemophilus influenzae were within the same range (0.5 to 1.5 μg/ml) whether or not...
Yourassowsky, E., Vanderlinden, M. P., Lismont, M. J., Schoutens, E.
The killing rate of a zonal concentration gradient of penicillin G on Staphylococcus aureus was studied by using a previously described triple-layer technique, enzymatic inactivation of the...
Speed of Bactericidal Action of Penicillin G, Ampicillin, and Carbenicillin on Bacteroides fragilis
Schoutens, E., Yourassowsky, E.
In order to determine the therapeutic value of penicillins in the management of anaerobic infections caused by Bacteroides fragilis, the antibacterial activity of penicillin G, ampicillin, and...
Sensitivity of Streptococcus pyogenes to sulphamethoxazole, trimethoprim, and cotrimoxazole
Yourassowsky, E., Vanderlinden, M. P., Schoutens, E.
When tested on Wellcotest (sensitivity test agar, Wellcome) supplemented with lysed horse blood, 59 clinical isolates of beta-haemolytic streptococci, belonging to several serological groups, are all...
Hansen, W, Schoutens, E, Yourassowsky, E
One hundred and twenty-two clinical isolates of Acinetobacter were studied for the presence of beta-galactosidase and of beta-xylosidase, for biochemical characteristics, and for genetic interspecies...
Yourassowsky, E, Van Der Linden, MP, Lismont, MJ, Crokaert, F
Methicillin- and gentamicin-resistant Staphylococcus aureus may remain sensitive to minocycline and to rifampicin. A study of growth curves has shown that at inhibitory concentrations (0·4 μg/ml),...
Yourassowsky, E, Van Der Linden, M P, Schoutens, E
When Haemophilus influenzae infections are treated by an antibiotic acting on the bacterial wall, the adequacy of antimicrobial therapy can be assessed by Schlichter's test. This test may be carried...
Hansen, W, Schoutens, E, Yourassowsky, E
A total of 314 strains of Haemophilus, isolated from clinical samples, were studied for the production of beta-galactosidase and beta-xylosidase. None of the H. influenzae strains studied (9...
Detection of Bacteroides fragilis and Bacteroides melaninogenicus by direct immunofluorescence.
Labbé, M, Delamare, N, Pepersack, F, Crokaert, F, Yourassowsky, E
A new diagnostic kit, which contains a polyvalent antiserum for either Bacteroides fragilis or Bacteroides melaninogenicus, was tested for reliability and specificity on 146 clinical samples of...
In-vitro activity of antimicrobial agents against Neisseria gonorrhoeae in Brussels.
Vanhoof, R, Vanderlinden, M P, Hubrechts, J M, Butzler, J P, Yourassowsky, E
The minimum inhibitory concentrations (MICs) of 18 antimicrobial agents against 104 strains of Neisseria gonorrhoeae isolated in the Brussels area between January and October 1976 have been measured....