Earl May

Staphylococcus aureus DNA ligase: characterization of its kinetics of catalysis and development of a high-throughput screening compatible chemiluminescent hybridization protection assay

Gul, Sheraz, Brown, Richard, May, Earl, Mazzulla, Marie, Smyth, Martin G., Berry, Colin, ...

DNA ligases are key enzymes involved in the repair and replication of DNA. Prokaryotic DNA ligases uniquely use NAD+ as the adenylate donor during catalysis, whereas eukaryotic enzymes use ATP. This...

Fluorescence Polarization Method To Characterize Macrolide-Ribosome Interactions

Yan, Kang, Hunt, Eric, Berge, John, May, Earl, Copeland, Robert A., Gontarek, Richard R.

A fluorescence polarization assay is described that measures the binding of fluorescently labeled erythromycin to 70S ribosomes from Escherichia coli and the displacement of the erythromycin from...

Staphylococcus aureus DNA ligase: characterization of its kinetics of catalysis and development of a high-throughput screening compatible chemiluminescent hybridization protection assay

Gul, Sheraz, Brown, Richard, May, Earl, Mazzulla, Marie, Smyth, Martin G., Berry, Colin, ...

DNA ligases are key enzymes involved in the repair and replication of DNA. Prokaryotic DNA ligases uniquely use NAD+ as the adenylate donor during catalysis, whereas eukaryotic enzymes use ATP. This...

Fluorescence Polarization Method To Characterize Macrolide-Ribosome Interactions

Yan, Kang, Hunt, Eric, Berge, John, May, Earl, Copeland, Robert A., Gontarek, Richard R.

A fluorescence polarization assay is described that measures the binding of fluorescently labeled erythromycin to 70S ribosomes from Escherichia coli and the displacement of the erythromycin from...