Cantú De León, David, Pérez-Montiel, Delia, Villavicencio, Verónica, Carranca, Alejandro, Betancourt, Alejandro, Acuña-Alonzo, Victor, ...
Abstract Background The development of breast cancer is multifactorial. Hormonal, environmental factors and genetic predisposition, among others, could interact in the presentation of breast...
Ingrid Almeciga, Zhigang Charles Wang, Joaquin Zúñiga, Marcelo Fern, Olga Clavijo, Hugo Araujo, ...
We identified and characterized an HLA-A1 aberrant allele (A*0118N) resulting from a novel molecular mechanism; this allele was present in an unusually informative family with a near identical...
Romero, Viviana, Larsen, Charles E, Duke-Cohan, Jonathan S, Fox, Edward A, Romero, Tatiana, Clavijo, Olga P, ...
Abstract Background The definition of human MHC class I haplotypes through association of HLA-A, HLA-Cw and HLA-B has been used to analyze ethnicity, population migrations and disease association....
Wang, Zhigang C., Hill, Joseph A., Yunis, Edmond J., Xiao, Ling, Anderson, Deborah J.
BACKGROUND: Women with recurrent pregnancy loss (RPL) and T-helper (Th)1-type immunity to trophoblast antigens have an increased frequency of the IL1B-511*1 promoter variant. Since CD46 gene products...
Wang, Zhigang C., Hill, Joseph A., Yunis, Edmond J., Xiao, Ling, Anderson, Deborah J.
BACKGROUND: Women with recurrent pregnancy loss (RPL) and T-helper (Th)1-type immunity to trophoblast antigens have an increased frequency of the IL1B-511*1 promoter variant. Since CD46 gene products...
MHC class I antigens regulate CD3-induced tyrosine phosphorylation of proteins in T cells (1994)
Dev Dasgupta, Jal, Granja, Clarissa B., Yunis, Edmond J., Relias, Valerie
The MHC class I antigens enhance the T cell response to various mltogenlc stimuli. Class I antigens co-cap and associate with the CD3 structure on these cells. The present work shows that...
Immnology and aging / edited Takashi Makinodan and Edmond Yunis (1977)
Incluye bibliografía e índice
Identification of phylogenetic footprints in primate tumor necrosis factor-α promoters
Leung, Jessica Y., McKenzie, F. Ellis, Uglialoro, Adele M., Flores-Villanueva, Pedro O., Sorkin, Barbara C., Yunis, Edmond J., ...
The human tumor necrosis factor-α (TNF-α) gene encodes a pleiotropic cytokine that plays a critical role in basic immunologic processes. To investigate the TNF-α regulatory region in the primate...
Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity
Flores-Villanueva, Pedro O., Yunis, Edmond J., Delgado, Julio C., Vittinghoff, Eric, Buchbinder, Susan, Leung, Jessica Y., ...
Certain HLA-B antigens have been associated with lack of progression to AIDS. HLA-B alleles can be divided into two mutually exclusive groups based on the expression of the molecular epitopes HLA-Bw4...
Delgado, Julio C., Tsai, Eunice Y., Thim, Sok, Baena, Andres, Boussiotis, Vassiliki A., Reynes, Jean-Marc, ...
Purified protein derivative (PPD) skin testing is used to identify persons infected with Mycobacterium tuberculosis (Mtb) and to assess cell-mediated immune responses to Mtb. However, lack of skin...
Studies of human sera with cytotoxic activity
Williams, Ralph C., Emmons, Jean D., Yunis, Edmond J.
42 human sera showing in vitro cytotoxic activity of restricted or broad HL-A specificities with test human lymphocytes were studied for the molecular and immunoglobulin class of cytotoxic antibody...
IL-10–producing T cells suppress immune responses in anergic tuberculosis patients
Boussiotis, Vassiliki A., Tsai, Eunice Y., Yunis, Edmond J., Thim, Sok, Delgado, Julio C., Dascher, Christopher C., ...
The lethality of Mycobacterium tuberculosis remains the highest among infectious organisms and is linked to inadequate immune response of the host. Containment and cure of tuberculosis requires an...
The Histocompatibility System in Juvenile, Insulin-Dependent Diabetic Multiplex Kindreds
Barbosa, Jose, King, Richard, Noreen, Harriet, Yunis, Edmond J.
We have histocompatibility (HLA) genotyped 24 families with two or more juvenile, insulin-dependent, ketosis-prone diabetic siblings. This criterion for family selection was used to obtain a...
Two Separate Genes Controlling Stimulation in Mixed Lymphocyte Reaction in Man
Dupont, Bo, Good, Robert A., Hansen, Grete S., Jersild, Casper, Nielsen, Lillian Staub, Park, Ben H., ...
The genetic control of strong stimulation in the mixed lymphocyte culture reaction is determined by a separate gene (MLR-S) closely linked to the FOUR-locus of the HL-A chromosomal region. Three...
Effect of Transfer Factor Therapy on Mixed Lymphocyte Culture Reactivity
Dupont, Bo, Ballow, Mark, Hansen, John A., Quick, Cedric, Yunis, Edmond J., Good, Robert A.
We have studied the effect of dialyzable transfer factor therapy on three patients with immunodeficiency disease and in one patient who demonstrated no evidence of deficiency of either humoral or...
Traits That Influence Longevity in Mice
Yunis, Edmond J., Watson, Ada L. M., Gelman, Rebecca S., Sylvia, Sherrill J., Bronson, Roderick, Dore, Martin E.
Analysis of genetic interactions in the segregating backcross [(C57BL/6 x DBA/2)F1 x DBA/2] mice revealed influences of genetic and environmental factors on life span. Using determinants of coat...
Identification of phylogenetic footprints in primate tumor necrosis factor-α promoters
Leung, Jessica Y., McKenzie, F. Ellis, Uglialoro, Adele M., Flores-Villanueva, Pedro O., Sorkin, Barbara C., Yunis, Edmond J., ...
The human tumor necrosis factor-α (TNF-α) gene encodes a pleiotropic cytokine that plays a critical role in basic immunologic processes. To investigate the TNF-α regulatory region in the primate...
Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity
Flores-Villanueva, Pedro O., Yunis, Edmond J., Delgado, Julio C., Vittinghoff, Eric, Buchbinder, Susan, Leung, Jessica Y., ...
Certain HLA-B antigens have been associated with lack of progression to AIDS. HLA-B alleles can be divided into two mutually exclusive groups based on the expression of the molecular epitopes HLA-Bw4...
Delgado, Julio C., Tsai, Eunice Y., Thim, Sok, Baena, Andres, Boussiotis, Vassiliki A., Reynes, Jean-Marc, ...
Purified protein derivative (PPD) skin testing is used to identify persons infected with Mycobacterium tuberculosis (Mtb) and to assess cell-mediated immune responses to Mtb. However, lack of skin...
Studies of human sera with cytotoxic activity
Williams, Ralph C., Emmons, Jean D., Yunis, Edmond J.
42 human sera showing in vitro cytotoxic activity of restricted or broad HL-A specificities with test human lymphocytes were studied for the molecular and immunoglobulin class of cytotoxic antibody...
IL-10–producing T cells suppress immune responses in anergic tuberculosis patients
Boussiotis, Vassiliki A., Tsai, Eunice Y., Yunis, Edmond J., Thim, Sok, Delgado, Julio C., Dascher, Christopher C., ...
The lethality of Mycobacterium tuberculosis remains the highest among infectious organisms and is linked to inadequate immune response of the host. Containment and cure of tuberculosis requires an...
The Histocompatibility System in Juvenile, Insulin-Dependent Diabetic Multiplex Kindreds
Barbosa, Jose, King, Richard, Noreen, Harriet, Yunis, Edmond J.
We have histocompatibility (HLA) genotyped 24 families with two or more juvenile, insulin-dependent, ketosis-prone diabetic siblings. This criterion for family selection was used to obtain a...
Two Separate Genes Controlling Stimulation in Mixed Lymphocyte Reaction in Man
Dupont, Bo, Good, Robert A., Hansen, Grete S., Jersild, Casper, Nielsen, Lillian Staub, Park, Ben H., ...
The genetic control of strong stimulation in the mixed lymphocyte culture reaction is determined by a separate gene (MLR-S) closely linked to the FOUR-locus of the HL-A chromosomal region. Three...
Effect of Transfer Factor Therapy on Mixed Lymphocyte Culture Reactivity
Dupont, Bo, Ballow, Mark, Hansen, John A., Quick, Cedric, Yunis, Edmond J., Good, Robert A.
We have studied the effect of dialyzable transfer factor therapy on three patients with immunodeficiency disease and in one patient who demonstrated no evidence of deficiency of either humoral or...
Traits That Influence Longevity in Mice
Yunis, Edmond J., Watson, Ada L. M., Gelman, Rebecca S., Sylvia, Sherrill J., Bronson, Roderick, Dore, Martin E.
Analysis of genetic interactions in the segregating backcross [(C57BL/6 x DBA/2)F1 x DBA/2] mice revealed influences of genetic and environmental factors on life span. Using determinants of coat...
Complex expression of natural killer receptor genes in single natural killer cells
Husain, Zaheed, Alper, Chester A, Yunis, Edmond J, Dubey, Devendra P
Human natural killer (NK) cells express several inhibitory and non-inhibitory NK receptors per cell. Understanding the expression patterns of these receptor genes in individual cells is important to...
Romero, Viviana, Larsen, Charles E, Duke-Cohan, Jonathan S, Fox, Edward A, Romero, Tatiana, Clavijo, Olga P, ...
STUDIES ON IMMUNOLOGIC RECONSTITUTION OF THYMECTOMIZED MICE
Yunis, Edmond J., Hilgard, Henry R., Martinez, Carlos, Good, Robert A.
1. Immunologic function, growth, and longevity of neonatally thymectomized mice was restored by intraperitoneal administration of 100 to 400 million syngeneic, hemiallogeneic, or ailogeneic thymus...
Yunis, Edmond J., Hong, Richard, Grewe, Mary Alice, Martinez, Carlos, Cornelius, Eugene, Good, Robert A.
1. Mice of A and C57BL/6 Ks strains, thymectomized at birth acquire wasting disease in 84.1% (A) and 77.1% (C57BL/6 Ks) of the cases. There is no sex predelection. 2. Anemia in these animals is...
Stutman, Osias, Yunis, Edmond J., Good, Robert A.
A progressive decrease of the restoring effectivity of syngeneic or allogeneic thymus and functional thymoma grafts was observed when the treatment of neonatally thymectomized mice was delayed. Early...
Stutman, Osias, Yunis, Edmond J., Good, Robert A.
Immunological restoration of 45-day old, neonatally thymectomized C3Hf mice by treatment with humoral thymic function (thymoma grafts, thymus or thymoma in diffusion chambers) ranges from 0 to 12%...
Stutman, Osias, Yunis, Edmond J., Good, Robert A.
Significant immunological restoration of 45-day old, neonatally thymectomized C3Hf mice was obtained by the cooperation of syngeneic newborn or embryonic hemopoietic liver cells with thymic function....
STUDIES ON THYMUS FUNCTION : III. DURATION OF THYMIC FUNCTION
Stutman, Osias, Yunis, Edmond J., Good, Robert A.
The immune functions of neonatally thymectomized C3Hf mice exposed only temporarily to thymus function show a progressive decay with time in the absence of the thymus. The immune responses studied at...