Edmund N. Browne

MCP-1 promoter variant -362C associated with protection from pulmonary tuberculosis in Ghana, West Africa (2009)

Thye, Thorsten, Nejentsev, Sergey, Intemann, Christopher D., Browne, Edmund N., Chinbuah, Margaret Amanua, Gyapong, John, ...

Current endeavour focuses on human genetic factors that contribute to susceptibility to or protection from tuberculosis (TB). Monocytes are crucial in containing Mycobacterium tuberculosis infection,...

Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: A report from three study sites in sub-Saharan Africa (2008)

Ajayi, Ikeoluwapo O, Browne, Edmund N, Bateganya, Fred, Yar, Denis, Happi, Christian, Falade, Catherine O, ...

Abstract Background The use of artemisinin-based combination therapy (ACT) at the community level has been advocated as a means to increase access to effective antimalarial medicines by high risk...

Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites (2008)

Ajayi, Ikeoluwapo O, Browne, Edmund N, Garshong, Bertha, Bateganya, Fred, Yusuf, Bidemi, Agyei-Baffour, Peter, ...

Abstract Background The Home Management of Malaria (HMM) strategy was developed using chloroquine, a now obsolete drug, which has been replaced by artemisinin-based combination therapy (ACT) in...

High Prevalence of Markers for Sulfadoxine and Pyrimethamine Resistance in Plasmodium falciparum in the Absence of Drug Pressure in the Ashanti Region of Ghana

Marks, Florian, Evans, Jennifer, Meyer, Christian G., Browne, Edmund N., Flessner, Christa, Von Kalckreuth, Vera, ...

Markers of Plasmodium falciparum resistance to chloroquine (CQ) and pyrimethamine-sulfadoxine (PYR-SDX) are widespread in areas where malaria is endemic. In an area where the use PYR-SDX is...

High Prevalence of Markers for Sulfadoxine and Pyrimethamine Resistance in Plasmodium falciparum in the Absence of Drug Pressure in the Ashanti Region of Ghana

Marks, Florian, Evans, Jennifer, Meyer, Christian G., Browne, Edmund N., Flessner, Christa, Von Kalckreuth, Vera, ...

Markers of Plasmodium falciparum resistance to chloroquine (CQ) and pyrimethamine-sulfadoxine (PYR-SDX) are widespread in areas where malaria is endemic. In an area where the use PYR-SDX is...

Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites

Ajayi, Ikeoluwapo O, Browne, Edmund N, Garshong, Bertha, Bateganya, Fred, Yusuf, Bidemi, Agyei-Baffour, Peter, ...

Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: A report from three study sites in sub-Saharan Africa

Ajayi, Ikeoluwapo O, Browne, Edmund N, Bateganya, Fred, Yar, Denis, Happi, Christian, Falade, Catherine O, ...

IL10 Haplotype Associated with Tuberculin Skin Test Response but Not with Pulmonary TB

Thye, Thorsten, Browne, Edmund N., Chinbuah, Margaret A., Gyapong, John, Osei, Ivy, Owusu-Dabo, Ellis, ...

Evidence from genetic association and twin studies indicates that susceptibility to tuberculosis (TB) is under genetic control. One gene implicated in susceptibility to TB is that encoding...