Sakurai, Yoshihiko, Brand, David D, Tang, Bo, Rosloniec, Edward F, Stuart, John M, Kang, Andrew H, ...
Abstract Rheumatoid arthritis (RA) is an autoimmune disease associated with the recognition of self proteins secluded in diarthrodial joints. We have previously established that mice transgenic for...
Paradoxical roles of IFN-γ in models of Th1-mediated autoimmunity (2002)
Rosloniec, Edward F, Latham, Kary, Guedez, Yajaira B
Abstract T-cell responses to antigens are classified on the basis of the cytokines they produce as either Th1 (IFN-γ, IL-2) or Th2 (IL-4, IL-10), with these Th types being indicative of either...
Wade, William F., Ward, Elizabeth De Pirro, Rosloniec, Edward F., Barlsas, B. George, Freed, John H.
Antigen presenting cells (APC) expressing MHC class II molecules composed of chains with part or all of the cytoplasmic domains deleted are Inefficient at presenting hen egg lysozyme peptides to...
Fridkis-Hareli, Masha, Rosloniec, Edward F., Fugger, Lars, Strominger, Jack L.
Copolymer 1 [poly(Y,E,A,K)] is a random synthetic amino acid copolymer of l-tyrosine, l-glutamic acid, l-alanine, and l-lysine that is effective both in suppression of experimental allergic...
Kotzin, Brian L., Falta, Michael T., Crawford, Frances, Rosloniec, Edward F., Bill, Jerry, Marrack, Philippa, ...
Considerable evidence indicates that CD4+ T cells are important in the pathogenesis of rheumatoid arthritis (RA), but the antigens recognized by these T cells in the joints of patients remain...
Paradoxical roles of IFN-γ in models of Th1-mediated autoimmunity
Rosloniec, Edward F, Latham, Kary, Guedez, Yajaira B
T-cell responses to antigens are classified on the basis of the cytokines they produce as either Th1 (IFN-γ, IL-2) or Th2 (IL-4, IL-10), with these Th types being indicative of either cell-mediated...
Fridkis-Hareli, Masha, Rosloniec, Edward F., Fugger, Lars, Strominger, Jack L.
Copolymer 1 [poly(Y,E,A,K)] is a random synthetic amino acid copolymer of l-tyrosine, l-glutamic acid, l-alanine, and l-lysine that is effective both in suppression of experimental allergic...
Kotzin, Brian L., Falta, Michael T., Crawford, Frances, Rosloniec, Edward F., Bill, Jerry, Marrack, Philippa, ...
Considerable evidence indicates that CD4+ T cells are important in the pathogenesis of rheumatoid arthritis (RA), but the antigens recognized by these T cells in the joints of patients remain...
Paradoxical roles of IFN-γ in models of Th1-mediated autoimmunity
Rosloniec, Edward F, Latham, Kary, Guedez, Yajaira B
T-cell responses to antigens are classified on the basis of the cytokines they produce as either Th1 (IFN-γ, IL-2) or Th2 (IL-4, IL-10), with these Th types being indicative of either cell-mediated...
Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB1*0401) transgenic mice
Sakurai, Yoshihiko, Brand, David D, Tang, Bo, Rosloniec, Edward F, Stuart, John M, Kang, Andrew H, ...
Rheumatoid arthritis (RA) is an autoimmune disease associated with the recognition of self proteins secluded in diarthrodial joints. We have previously established that mice transgenic for the human...
Molecular characterization of an arthritogenic collagen peptide interacting with I-Ar
Sakurai, Yoshihiko, Tang, Bo, Rosloniec, Edward F, Stuart, John M, Kang, Andrew H, Myers, Linda K
Collagen-induced arthritis (CIA) is an autoimmune arthritis that can be elicited by the immunization of genetically susceptible strains of mice with type II collagen (CII). We have analysed the...
Rosloniec, Edward F., Brand, David D., Myers, Linda K., Whittington, Karen B., Gumanovskaya, Marina, Zaller, Dennis M., ...
Rheumatoid arthritis (RA) is an autoimmune disease that is strongly associated with the expression of several HLA-DR haplotypes, including DR1 (DRB1*0101). Although the antigen that initiates RA...