Edward Giovannucci

On the epidemiology of influenza: reply to Radonovich et al (2009)

Cannell, John J, Zasloff, Michael, Garland, Cedric F, Scragg, Robert, Giovannucci, Edward

Abstract On the epidemiology of influenza: reply to Radonovich LJ, Martinello RA, Hodgson M, Milton DK, Nardell EA. Influenza and ultraviolet germicidal irradiation. Virol J. 2008, 5:149

Prevalence and correlates of vitamin D status in African American men (2009)

Tseng, Marilyn, Giri, Veda, Bruner, Deborah W, Giovannucci, Edward

Abstract Background Few studies have examined vitamin D insufficiency in African American men although they are at very high risk. We examined the prevalence and correlates of vitamin D insufficiency...

Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3) (2009)

Ahn, Jiyoung, Schumacher, Fredrick R., Berndt, Sonja I., Pfeiffer, Ruth, Albanes, Demetrius, Andriole, Gerald L., ...

Twin studies suggest a heritable component to circulating sex steroid hormones and sex hormone-binding globulin (SHBG). In the NCI-Breast and Prostate Cancer Cohort Consortium, 874 SNPs in 37...

The Relationship between a Polymorphism in CYP17 with Plasma Hormone Levels and Prostate Cancer 1 (2008)

Christopher A. Haiman, Meir J. Stampfer, Edward Giovannucci, Jing Ma, Niv E. Decalo, Philip W. Kantoff, ...

The A2 allele of the CYP17 gene has been thought to be associated with increased functional activity of this steroidogenic enzyme. Consequently, the A2 allele has been examined as a biomarker of...

25-hydroxyvitamin D and risk of myocardial infarction in men - A prospective study (2008)

Giovannucci, Edward, Liu, Yan, Hollis, Bruce W., Rimm, Eric B.

Background: Vitamin D deficiency may be involved in the development of atherosclerosis and coronary heart disease in humans. Methods: We assessed prospectively whether plasma 25-hydroxyvitamin D...

On the epidemiology of influenza (2008)

Cannell, John J, Zasloff, Michael, Garland, Cedric F, Scragg, Robert, Giovannucci, Edward

Abstract The epidemiology of influenza swarms with incongruities, incongruities exhaustively detailed by the late British epidemiologist, Edgar Hope-Simpson. He was the first to propose a...

On the epidemiology of influenza (2008)

Cannell, John, Zasloff, Michael, Garland, Cedric, Scragg, Robert, Giovannucci, Edward

An open access copy of this article is available and complies with the copyright holder/publisher conditions.

Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk (2008)

Berndt, Sonja I., Potter, John D., Hazra, Aditi, Yeager, Meredith, Thomas, Gilles, Makar, Karen W., ...

Several different genetic variants at chromosome 8q24 have been related to prostate, breast and colorectal cancer risk with evidence of region-specific risk differentials for various tumor types. We...

Sequence variants of elaC homolog 2 (Escherichia coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up Study (2008)

Chen, Yen-Ching, Giovannucci, Edward, Kraft, Peter, J.Hunter, David

Two non-synonymous single-nucleotide polymorphisms (SNPs), Ser217Leu and Ala541Thr, in the elaC homolog 2 (Escherichia coli) (ELAC2) gene have been related to prostate cancer risk in previous...

Manganese superoxide dismutase (MnSOD) gene polymorphism, interactions with carotenoid levels and prostate cancer risk (2008)

Mikhak, Bahar, Hunter, David J., Spiegelman, Donna, Platz, Elizabeth A., Wu, Kana, Erdman, John W., ...

Background: The manganese superoxide dismutase (MnSOD) gene encodes an antioxidant enzyme (SOD2) that may protect cells from oxidative damage. The MnSOD allele with Val as amino acid 16 encodes a...

Alcohol Intake and Renal Cell Cancer in a Pooled Analysis of 12 Prospective Studies (2007)

Lee, Jung Eun, Hunter, David J., Spiegelman, Donna, Adami, Hans-Olov, Albanes, Demetrius, Bernstein, Leslie, ...

Background The association between alcohol intake and risk of renal cell cancer has been inconsistent in case–control studies. An inverse association between alcohol intake and risk of renal cell...

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. (2007)

Yeager, Meredith, Orr, Nick, Hayes, Richard B., Jacobs, Kevin B., Kraft, Peter, Wacholder, Sholom, ...

Recently, common variants on human chromosome 8q24 were found to be associated with prostate cancer risk. While conducting a genome-wide association study in the Cancer Genetic Markers of...

Folate and Risk of Breast Cancer: A Meta-analysis (2007)

Larsson, Susanna C., Giovannucci, Edward, Wolk, Alicja

Background Epidemiologic findings are inconsistent concerning risk for breast cancer associated with low folate intake or blood folate levels. We performed a meta-analysis of prospective and...

A Prospective Study of Periodontal Disease and Pancreatic Cancer in US Male Health Professionals (2007)

Michaud, Dominique S., Joshipura, Kaumudi, Giovannucci, Edward, Fuchs, Charles S.

Two previous cohort studies reported positive associations between tooth loss or periodontitis and pancreatic cancer risk. Data on periodontal disease were obtained at baseline and every other year...

Dietary Carotenoids and Risk of Colorectal Cancer in a Pooled Analysis of 11 Cohort Studies (2007)

Männistö, Satu, Yaun, Shiaw-Shyuan, Hunter, David J., Spiegelman, Donna, Adami, Hans-Olov, Albanes, Demetrius, ...

Dietary carotenoids have been hypothesized to protect against epithelial cancers. The authors analyzed the associations between intakes of specific carotenoids (alpha-carotene, beta-carotene,...

Dietary Carbohydrate, Glycemic Index, and Glycemic Load in Relation to Risk of Colorectal Cancer in Women (2007)

Larsson, Susanna C., Giovannucci, Edward, Wolk, Alicja

Diets with a high glycemic index and glycemic load have been hypothesized to be implicated in the etiology of colorectal cancer owing to their potential to increase postprandial glucose and insulin...

Coffee Consumption and Incidence of Colorectal Cancer in Two Prospective Cohort Studies of Swedish Women and Men (2006)

Larsson, Susanna C., Bergkvist, Leif, Giovannucci, Edward, Wolk, Alicja

Investigators have reported an inverse association between coffee consumption and risk of colorectal cancer in several case-control studies, but prospective studies, most of them involving small...

Prospective Study of Fruits and Vegetables and Risk of Oral Premalignant Lesions in Men (2006)

Maserejian, Nancy Nairi, Giovannucci, Edward, Rosner, Bernard, Zavras, Athanasios, Joshipura, Kaumudi

The authors prospectively evaluated fruit and vegetable consumption and the incidence of oral premalignant lesions among 42,311 US men in the Health Professionals Follow-up Study. Diet was assessed...

Statin Drugs and Risk of Advanced Prostate Cancer (2006)

Platz, Elizabeth A., Leitzmann, Michael F., Visvanathan, Kala, Rimm, Eric B., Stampfer, Meir J., Willett, Walter C., ...

Background: Statins are commonly used cholesterol-lowering drugs that have proapoptotic and antimetastatic activities that could affect cancer risk or progression. Results from previous epidemiologic...

Flavonoid Intake and Colorectal Cancer Risk in Men and Women (2006)

Lin, Jennifer, Zhang, Shumin M., Wu, Kana, Willett, Walter C., Fuchs, Charles S., Giovannucci, Edward

Dietary flavonoids can inhibit cancer development by protecting tissues against free oxygen radicals and inhibiting cell proliferation, but observational studies of flavonoid intake and colorectal...

Prospective Study of Predictors of Vitamin D Status and Cancer Incidence and Mortality in Men (2006)

Giovannucci, Edward, Liu, Yan, Rimm, Eric B., Hollis, Bruce W., Fuchs, Charles S., Stampfer, Meir J., ...

Background: Vitamin D has potent anticancer properties, especially against digestive-system cancers. Many human studies have used geographic residence as a marker of solar ultraviolet B and hence...

Methods for Pooling Results of Epidemiologic Studies: The Pooling Project of Prospective Studies of Diet and Cancer (2006)

Smith-Warner, Stephanie A., Spiegelman, Donna, Ritz, John, Albanes, Demetrius, Beeson, W. Lawrence, Bernstein, Leslie, ...

With the growing number of epidemiologic publications on the relation between dietary factors and cancer risk, pooled analyses that summarize results from multiple studies are becoming more common....

Folate Intake and Pancreatic Cancer Incidence: A Prospective Study of Swedish Women and Men (2006)

Larsson, Susanna C., Håkansson, Niclas, Giovannucci, Edward, Wolk, Alicja

Background: Epidemiologic evidence supports an association between high folate intake and reduced risk of some cancers, in particular colorectal cancer. However, epidemiologic data concerning the...

Intake of Folate and Related Nutrients in Relation to Risk of Epithelial Ovarian Cancer (2006)

Tworoger, Shelley S., Hecht, Jonathan L., Giovannucci, Edward, Hankinson, Susan E.

Assessments of the relation between folate intake and ovarian cancer risk have been limited and inconsistent. Therefore, the authors prospectively examined the association of dietary and supplemental...

Genetic variation in the HSD17B1 gene and risk of prostate cancer (2005)

Peter Kraft, Richard B. Hayes, Paul D. Pharoah, Stephen Chanock, Demetrius Albanes, Laurence N. Kolonel, ...

Steroid hormones are believed to play an important role in prostate carcinogenesis, but epidemiological evidence linking prostate cancer and related genes has been inconclusive, in part due to small...

Sexually Transmitted Infections, Prostatitis, Ejaculation Frequency, and the Odds of Lower Urinary Tract Symptoms (2005)

Sutcliffe, Siobhan, Giovannucci, Edward, De Marzo, Angelo M., Willett, Walter C., Platz, Elizabeth A.

Early life sexual factors, including histories of sexually transmitted infections, young-onset prostatitis, and frequency of ejaculation, were investigated in relation to lower urinary tract symptoms...

Coffee, Tea, and Caffeine Consumption and Incidence of Colon and Rectal Cancer (2005)

Michels, Karin B., Willett, Walter C., Fuchs, Charles S., Giovannucci, Edward

Background: Frequent coffee consumption has been associated with a reduced risk of colorectal cancer in a number of case–control studies. Cohort studies have not revealed such an association but...

Sexually Transmitted Infections, Prostatitis, Ejaculation Frequency, and the Odds of Lower Urinary Tract Symptoms (2005)

Sutcliffe, Siobhan, Giovannucci, Edward, De Marzo, Angelo M., Willett, Walter C., Platz, Elizabeth A.

Early life sexual factors, including histories of sexually transmitted infections, young-onset prostatitis, and frequency of ejaculation, were investigated in relation to lower urinary tract symptoms...

Low Plasma Adiponectin Levels and Risk of Colorectal Cancer in Men: A Prospective Study (2005)

Wei, Esther K., Giovannucci, Edward, Fuchs, Charles S., Willett, Walter C., Mantzoros, Christos S.

Background: Adiponectin is an insulin-sensitizing hormone secreted by adipocytes. Levels of adiponectin are inversely associated with adiposity and insulin resistance. Because both adiposity and...

Dietary Patterns and Pancreatic Cancer Risk in Men and Women (2005)

Michaud, Dominique S., Skinner, Halcyon G., Wu, Kana, Hu, Frank, Giovannucci, Edward, Willett, Walter C., ...

Background: Diabetes appears to be associated with the development of pancreatic cancer. Three large prospective cohort studies observed a statistically significant relationbetween obesity and...

Plasma Vitamin B6 and the Risk of Colorectal Cancer and Adenoma in Women (2005)

Wei, Esther K., Giovannucci, Edward, Selhub, Jacob, Fuchs, Charles S., Hankinson, Susan E., Ma, Jing

Background: Vitamin B6, whose main circulating form is pyridoxal 5′-phosphate (PLP), is important in one-carbon metabolism, which is critical for DNA synthesis and DNA methylation, both of which...

Sexually Transmitted Infections, Prostatitis, Ejaculation Frequency, and the Odds of Lower Urinary Tract Symptoms (2005)

Sutcliffe, Siobhan, Giovannucci, Edward, De Marzo, Angelo M., Willett, Walter C., Platz, Elizabeth A.

Early life sexual factors, including histories of sexually transmitted infections, young-onset prostatitis, and frequency of ejaculation, were investigated in relation to lower urinary tract symptoms...

Dairy Foods, Calcium, and Colorectal Cancer: A Pooled Analysis of 10 Cohort Studies (2004)

Cho, Eunyoung, Smith-Warner, Stephanie A., Spiegelman, Donna, Beeson, W. Lawrence, Van Den Brandt, Piet A., Colditz, Graham A., ...

Background: Studies in animals have suggested that calcium may reduce the risk of colorectal cancer. However, results from epidemiologic studies of intake of calcium or dairy foods and colorectal...

Dietary Folate Intake and Incidence of Ovarian Cancer: The Swedish Mammography Cohort (2004)

Larsson, Susanna C., Giovannucci, Edward, Wolk, Alicja

Background: Mounting evidence suggests that a low intake of the water-soluble B vitamin folate is associated with breast and colorectal carcinogenesis, especially among alcohol drinkers. However,...

Height, predictors of C-peptide and cancer risk in men (2004)

Giovannucci, Edward, Rimm, Eric B, Liu, Yan, Willett, Walter C

Background Excessive energy intake tends to increase circulating levels of insulin and free insulin-like growth factor-1 (IGF-I), which may increase risk of some cancers that are common in Western...

Epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-Up Study (2004)

Tranah, Gregory J., Giovannucci, Edward, Ma, Jing, Fuchs, Charles, Hankinson, Susan E., Hunter, David J.

Microsomal epoxide hydrolase (mEH) is involved the bioactivation and detoxification of polycyclic aromatic hydrocarbons derived from tobacco smoke and charred meat intake. Two coding-region mEH...

Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up Study (2004)

Tranah, Gregory J., Giovannucci, Edward, Ma, Jing, Fuchs, Charles, Hankinson, Susan E., Hunter, David J.

Microsomal epoxide hydrolase (mEH) is involved in the bioactivation and detoxification of polycyclic aromatic hydrocarbons derived from tobacco smoke and charred meat intake. Two coding region mEH...

Dietary Glycemic Load and Risk of Colorectal Cancer in the Women's Health Study (2004)

Higginbotham, Susan, Zhang, Zuo-Feng, Lee, I-Min, Cook, Nancy R., Giovannucci, Edward, Buring, Julie E., ...

Although diet is believed to influence colorectal cancer risk, the long-term effects of a diet with a high glycemic load are unclear. The growing recognition that colorectal cancer may be promoted by...

Associations of Obesity with Lower Urinary Tract Symptoms and Noncancer Prostate Surgery in the Third National Health and Nutrition Examination Survey (2004)

Rohrmann, Sabine, Smit, Ellen, Giovannucci, Edward, Platz, Elizabeth A.

The authors examined the association between obesity and lower urinary tract symptoms (LUTS) in the Third National Health and Nutrition Examination Survey. This 1988–1994 US cross-sectional study...

A Prospective Study of Plasma C-Peptide and Colorectal Cancer Risk in Men (2004)

Ma, Jing, Giovannucci, Edward, Pollak, Michael, Leavitt, Azita, Tao, Yuzhen, Gaziano, J. Michael, ...

Background: Colorectal cancer and type 2 diabetes share many risk factors, and hyperinsulinemia appears to be associated with an increased risk of colorectal cancer. We used the concentration of...

A Prospective Study of Aspirin Use and the Risk of Pancreatic Cancer in Women (2004)

Schernhammer, Eva S., Kang, Jae-Hee, Chan, Andrew T., Michaud, Dominique S., Skinner, Halcyon G., Giovannucci, Edward, ...

Background: In vitro experiments and limited animal studies suggest that aspirin and nonsteroidal anti-inflammatory drugs may inhibit pancreatic carcinogenesis. Because few studies have examined the...

Prospective Study of Selenium Levels in Toenails and Risk of Coronary Heart Disease in Men (2003)

Yoshizawa, Kazuko, Ascherio, Alberto, Morris, J. Steven, Stampfer, Meir J., Giovannucci, Edward, Baskett, Connie K., ...

Selenium is a trace mineral that plays a role in antioxidant defenses as a component of glutathione peroxidase. Epidemiologic findings on the relation of selenium status to risk of heart disease are...

Dietary Meat, Dairy Products, Fat, and Cholesterol and Pancreatic Cancer Risk in a Prospective Study (2003)

Michaud, Dominique S., Giovannucci, Edward, Willett, Walter C., Colditz, Graham A., Fuchs, Charles S.

Case-control studies suggest that meat and cholesterol intakes may be related to elevated risks of pancreatic cancer. Few prospective studies have examined associations between diet and pancreatic...

Body Mass Index and Risk of Prostate Cancer in U.S. Health Professionals (2003)

Giovannucci, Edward, Rimm, Eric B., Liu, Yan, Leitzmann, Michael, Wu, Kana, Stampfer, Meir J., ...

The relationship between body mass index (BMI) and prostate cancer risk may be complex because obesity is associated with various hormonal factors and because the influence of BMI may differ...

Dietary Sugar, Glycemic Load, and Pancreatic Cancer Risk in a Prospective Study (2002)

Michaud, Dominique S., Liu, Simin, Giovannucci, Edward, Willett, Walter C., Colditz, Graham A., Fuchs, Charles S.

Background: Evidence from both animal and human studies suggests that abnormal glucose metabolism plays an important role in pancreatic carcinogenesis. We investigated whether diets high in foods...

A Prospective Study of Tomato Products, Lycopene, and Prostate Cancer Risk (2002)

Giovannucci, Edward, Rimm, Eric B., Liu, Yan, Stampfer, Meir J., Willett, Walter C.

Background: Some data, including our findings from the Health Professionals Follow-Up Study (HPFS) from 1986 through January 31, 1992, suggest that frequent intake of tomato products or lycopene, a...

Insulin-Like Growth Factor-I (IGF-I) and IGF Binding Protein-3 as Predictors of Advanced-Stage Prostate Cancer (2002)

Chan, June M., Stampfer, Meir J., Ma, Jing, Gann, Peter, Gaziano, J. Michael, Pollak, Michael, ...

Background: Plasma levels of insulin-like growth factor-I (IGF-I) have been associated with the risk of prostate cancer. However, the association of IGF-I with specific tumor stage and grade at...

Fruit, Vegetables, Dietary Fiber, and Risk of Colorectal Cancer (2001)

Terry, Paul, Giovannucci, Edward, Michels, Karin B., Bergkvist, Leif, Hansen, Holger, Holmberg, Lars, ...

Background: Several recent large prospective cohort studies have failed to demonstrate the presumed protective effect of fruit, vegetable, and dietary fiber consumption on colorectal cancer risk. To...

Prospective Study of Dietary Supplements, Macronutrients, Micronutrients, and Risk of Bladder Cancer in US Men (2000)

Michaud, Dominique S., Spiegelman, Donna, Clinton, Steven K., Rimm, Eric B., Willett, Walter C., Giovannucci, Edward

Data derived from laboratory investigations suggest that a number of dietary variables may contribute to bladder carcinogenesis. Although bladder cancer is the fourth leading cause of cancer in men...

Racial Variation in Prostate Cancer Incidence and in Hormonal System Markers Among Male Health Professionals (2000)

Platz, Elizabeth A., Rimm, Eric B., Willett, Walter C., Kantoff, Philip W., Giovannucci, Edward

Background: Racial variation in prostate cancer incidence in the United States is pronounced, with African-American men having the highest rates. Whether differences in the distribution of known or...

Prospective Study of Adult Onset Diabetes Mellitus (Type 2) and Risk of Colorectal Cancer in Women (1999)

Hu, Frank B., Manson, JoAnn E., Liu, Simin, Hunter, David, Colditz, Graham A., Michels, Karin B., ...

BACKGROUND: The remarkable similarity of lifestyle and environmental risk factors for type 2 (non-insulin-dependent) diabetes mellitus and colon cancer has led to the hypothesis that diabetes may...

Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF-Binding Protein-3 (1999)

Ma, Jing, Pollak, Michael N., Giovannucci, Edward, Chan, June M., Tao, Yuzhen, Hennekens, Charles H., ...

BACKGROUND: Insulin-like growth factor-I (IGF-I) is a potent mitogen for normal and neoplastic cells, whereas IGF-binding protein-3 (IGFBP-3) inhibits cell growth in many experimental systems....

Risk Factors for Basal Cell Carcinoma of the Skin in Men: Results from the Health Professionals Follow-up Study (1999)

Dam, Rob M. Van, Huang, Zhiping, Rimm, Eric B., Weinstock, Martin A., Spiegelman, Donna, Colditz, Graham A., ...

The authors examined the relation of constitutional factors and sun exposure to risk of basal cell carcinoma of the skin (BCC) in a prospective cohort of 44,591 predominantly Caucasian US male health...

Tomatoes, Tomato-Based Products, Lycopene, and Cancer: Review of the Epidemiologic Literature (1999)

Giovannucci, Edward

The epidemiologic literature in the English language regarding intake of tomatoes and tomato-based products and blood lycopene (a compound derived predominantly from tomatoes) level in relation to...

Alcohol Consumption, Cigarette Smoking, and Risk of Benign Prostatic Hyperplasia (1999)

Platz, Elizabeth A., Rimm, Eric B., Kawachi, Ichiro, Colditz, Graham A., Stampfer, Meir J., Willett, Walter C., ...

Alcohol consumption and cigarette smoking were evaluated in relation to development of benign prostatic hyperplasia (BPH) among 29,386 members of the Health Professionals Follow-up Study. Men who...

Meta-analysis of Coffee Consumption and Risk of Colorectal Cancer (1998)

Giovannucci, Edward

Several studies have found that coffee consumption is related to a lower risk of colorectal cancer, but results have not been consistent. Thus, a meta-analysis of the published articles was conducted...

Calcium, Vitamin D, and Dairy Foods and the Occurrence of Colon Cancer in Men (1996)

Keamey, John, Giovannucci, Edward, Rimm, Eric B., Ascherio, Alberto, Stampfer, Meir J., Colditz, Graham A., ...

To examine the associations between intakes of calcium, vitamin D, and dairy foods and the risk of colon cancer, the authors analyzed data from a prospective study of 47,935 US male health...

Tobacco, Colorectal Cancer, and Adenomas: a Review of the Evidence (1996)

Giovannucci, Edward, Martinez, Maria Elena

Although tobacco has been clearly implicated as a cause of a number of cancers, earlier studies had not generally found cigarette smokers to be at higher risk for cancers of the large bowel. Unlike...

Alcohol, Low-Methionine-Low-Folate Diets, and Risk of Colon Cancer in Men (1995)

Giovannucci, Edward, Rimm, Eric B., Ascherio, Alberto, Stampfer, Meir J., Colditz, Graham A., Willett, Walter C.

Background: Methylation of DNA, which may have a role in the regulation of gene expression, depends on dietary folate and methionine. Because aberrant DNA methylation may contribute to the initiation...

Intake of Carotenoids and Retino in Relation to Risk of Prostate Cancer (1995)

Giovannucci, Edward, Ascherio, Alberto, Rimm, Eric B., Stampfer, Meir J., Colditz, Graham A., Willett, Walter C.

Background: Several human studies have observed a direct association between retinol (vitamin A) intake and risk of prostate cancer; other studies have found either an inverse association or no...

Body Size and Fat Distribution as Predictors of Coronary Heart Disease among Middle-aged and Older US Men (1995)

Rimm, Eric B., Stampfer, Meir J., Giovannucci, Edward, Ascherio, Alberto, Spiegelman, Donna, Colditz, Graham A., ...

Obesity, android fat distribution, and other anthropometric measures have been associated with coronary heart disease in long-term prospective studies. However, fluctuations in weight due to...

Calcium, Vitamin D, Dairy Foods, and the Occurrence of Colorectal Adenomas among Men and Women in Two Prospective Studies (1994)

Kampman, Ellen, Giovannucci, Edward, Van't Veer, Pieter, Rimm, Enc, Stampfer, Meir J., Colditz, Graham A., ...

A high intake of calcium, vitamin D, or specific dairy products is thought to reduce the Incidence of colorectal cancer. The association of these nutrients and foods with the occurrence of colorectal...

A Prospective Study of Cigarette Smoking and Risk of Colorectal Adenoma and Colorectal Cancer in U.S. Men (1994)

Giovannucci, Edward, Rimm, Eric B., Stampfer, Meir J., Colditz, Graham A., Ascherio, Alberto, Kearney, John, ...

Background Epidemiologic studies of men consistently demonstrate a positive association between tobacco smoking and risk of colorectal adenomas, precursors of cancer, but have not consistently shown...

A Prospective Study of Cigarette Smoking and Risk of Colorectal Adenoma and Colorectal Cancer in U.S. Women (1994)

Giovannucci, Edward, Colditz, Graham A., Stampfer, Meir J., Hunter, David, Rosner, Bernard A., Willett, Walter C., ...

Background A positive correlation between smoking and colorectal cancer has been reported for men, but not for women, who began smoking in substantial numbers in the late 1940s and early 1950s. We...

Obesity and Benign Prostatic Hyperplasia (1994)

Giovannucci, Edward, Rimm, Eric B., Chute, Christopher G., Kawachi, Ichiro, Colditz, Graham A., Stampfer, Meir J., ...

Abdominal obesity increases the estrogen-to-androgen ratio and may increase sympathetic nervous activity, both hypothesized to influence the development of benign prostatic hyperplasia and the...

A Prospective Study of Dietary Fat and Risk of Prostate Cancer (1993)

Giovannucci, Edward, Rimm, Eric B., Colditz, Graham A., Stampfer, Meir J., Ascherio, Alberto, Chute, Chris C., ...

Background: The strong correlation between national consumption of fat and national rate of mortality from prostate cancer has raised the hypothesis that dietary fat increases the risk of this...

Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma (1993)

Giovannucci, Edward, Stampfer, Meir J., Colditz, Graham A., Rimm, Eric B., Trichopoulos, Dimitrios, Rosner, Bernard A., ...

Background: Reduced methylation of DNA may contribute to loss of the normal controls on proto-oncogene expression. In humans, hypomethylation of DNA has been observed in colorectal cancers and in...

A Comparison of Prospective and Retrospective Assessments of Diet in the Study of Breast Cancer (1993)

Giovannucci, Edward, Stampfer, Meir J., Colditz, Graham A., Manson, JoAnn E., Rosner, Bernard A., Longnecker, Matt, ...

Fat intake was examined in relation to risk of breast cancer using dietary questionnaires administered both before and after the diagnosis of breast cancer. Among the Nurses' Health Study cohort...

Relationship of Diet to Risk of Colorectal Adenoma in Men (1992)

Giovannucci, Edward, Stampfer, Meir J., Colditz, Graham, Rimm, Eric B., Willett, Walter C.

Background: Rates of colorectal cancer in various countries are strongly correlated with per-capita consumption of red meat and animal fat and inversely associated with fiber consumption. There have...

EFFECTIVENESS OF VARIOUS MAILING STRATEGIES AMONG NONRESPONDENTS IN A PROSPECTIVE COHORT STUDY (1990)

RIMM, ERIC B., STAMPFER, MEIR J., COLDITZ, GRAHAM A., GIOVANNUCCI, EDWARD, WILLETT, WALTER C.

Measures of association in prospective studies can be distorted by incomplete follow-up. Various mailing strategies were used to contact 12,233 cohort members of the Health Professionals Follow-up...

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

Giovannucci, Edward, Stampfer, Meir J., Krithivas, Krishna, Brown, Myles, Brufsky, Adam, Talcott, James, ...

The length of a polymorphic CAG repeat sequence, occurring in the androgen receptor gene, is inversely correlated with transcriptional activity by the androgen receptor. Because heightened androgenic...

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

Giovannucci, Edward, Stampfer, Meir J., Krithivas, Krishna, Brown, Myles, Brufsky, Adam, Talcott, James, ...

The length of a polymorphic CAG repeat sequence, occurring in the androgen receptor gene, is inversely correlated with transcriptional activity by the androgen receptor. Because heightened androgenic...

On the epidemiology of influenza

Cannell, John J, Zasloff, Michael, Garland, Cedric F, Scragg, Robert, Giovannucci, Edward

The epidemiology of influenza swarms with incongruities, incongruities exhaustively detailed by the late British epidemiologist, Edgar Hope-Simpson. He was the first to propose a parsimonious theory...

Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility

Lou, Hong, Yeager, Meredith, Li, Hongchuan, Bosquet, Jesus Gonzalez, Hayes, Richard B., Orr, Nick, ...

Two recent genome-wide association studies have independently identified a prostate cancer susceptibility locus on chromosome 10q11.2. The most significant single-nucleotide polymorphism (SNP) marker...

On the epidemiology of influenza: reply to Radonovich et al

Cannell, John J, Zasloff, Michael, Garland, Cedric F, Scragg, Robert, Giovannucci, Edward

On the epidemiology of influenza: reply to Radonovich LJ, Martinello RA, Hodgson M, Milton DK, Nardell EA. Influenza and ultraviolet germicidal irradiation. Virol J. 2008, 5:149