Burkholderia pseudomalleigenome plasticity associated with genomic island variation (2008)
Tumapa, Sarinna, Holden, Matthew TG, Vesaratchavest, Mongkol, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, Chierakul, Wirongrong, ...
Abstract Background Burkholderia pseudomallei is a soil-dwelling saprophyte and the cause of melioidosis. Horizontal gene transfer contributes to the genetic diversity of this pathogen and may be an...
Feil, Edward J., Holmes, Edward C., Bessen, Debra E., Chan, Man-Suen, Day, Nicholas P. J., Enright, Mark C., ...
The identification of clones within bacterial populations is often taken as evidence for a low rate of recombination, but the validity of this inference is rarely examined. We have used statistical...
The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
Enright, Mark C., Robinson, D. Ashley, Randle, Gaynor, Feil, Edward J., Grundmann, Hajo, Spratt, Brian G.
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital-acquired infections that are becoming increasingly difficult to combat because of emerging resistance to all current...
Meats, Emma, Feil, Edward J., Stringer, Suzanna, Cody, Alison J., Goldstein, Richard, Kroll, J. Simon, ...
A multilocus sequence typing (MLST) scheme has been developed for the unambiguous characterization of encapsulated and noncapsulated Haemophilus influenzae isolates. The sequences of internal...
Grundmann, Hajo, Hori, Satoshi, Enright, Mark C., Webster, Carol, Tami, Adriana, Feil, Edward J., ...
We used a sample of Staphylococcus aureus strains that are carried by humans and that are representative of the natural population of S. aureus strains in order to assess the value of multilocus...
Feil, Edward J., Li, Bao C., Aanensen, David M., Hanage, William P., Spratt, Brian G.
The introduction of multilocus sequence typing (MLST) for the precise characterization of isolates of bacterial pathogens has had a marked impact on both routine epidemiological surveillance and...
Holden, Matthew T. G., Feil, Edward J., Lindsay, Jodi A., Peacock, Sharon J., Day, Nicholas P. J., Enright, Mark C., ...
Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains, presenting a major...
Evolutionary Genetics of the Accessory Gene Regulator (agr) Locus in Staphylococcus aureus†
Robinson, D. Ashley, Monk, Alastair B., Cooper, Jessica E., Feil, Edward J., Enright, Mark C.
The accessory gene regulator (agr) locus influences the expression of many virulence genes in the human pathogen Staphylococcus aureus. Four allelic groups of agr, which generally inhibit the...
How Clonal Is Staphylococcus aureus?
Feil, Edward J., Cooper, Jessica E., Grundmann, Hajo, Robinson, D. Ashley, Enright, Mark C., Berendt, Tony, ...
Staphylococcus aureus is an important human pathogen and represents a growing public health burden owing to the emergence and spread of antibiotic-resistant clones, particularly within the hospital...
Vesaratchavest, Mongkol, Tumapa, Sarinna, Day, Nicholas P. J., Wuthiekanun, Vanaporn, Chierakul, Wirongrong, Holden, Matthew T. G., ...
Burkholderia pseudomallei is a soil-dwelling saprophyte and the causative agent of melioidosis, a life-threatening human infection. Most cases are reported from northeast Thailand and northern...
Feil, Edward J., Holmes, Edward C., Bessen, Debra E., Chan, Man-Suen, Day, Nicholas P. J., Enright, Mark C., ...
The identification of clones within bacterial populations is often taken as evidence for a low rate of recombination, but the validity of this inference is rarely examined. We have used statistical...
The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
Enright, Mark C., Robinson, D. Ashley, Randle, Gaynor, Feil, Edward J., Grundmann, Hajo, Spratt, Brian G.
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital-acquired infections that are becoming increasingly difficult to combat because of emerging resistance to all current...
Meats, Emma, Feil, Edward J., Stringer, Suzanna, Cody, Alison J., Goldstein, Richard, Kroll, J. Simon, ...
A multilocus sequence typing (MLST) scheme has been developed for the unambiguous characterization of encapsulated and noncapsulated Haemophilus influenzae isolates. The sequences of internal...
Grundmann, Hajo, Hori, Satoshi, Enright, Mark C., Webster, Carol, Tami, Adriana, Feil, Edward J., ...
We used a sample of Staphylococcus aureus strains that are carried by humans and that are representative of the natural population of S. aureus strains in order to assess the value of multilocus...
How Clonal Is Staphylococcus aureus?
Feil, Edward J., Cooper, Jessica E., Grundmann, Hajo, Robinson, D. Ashley, Enright, Mark C., Berendt, Tony, ...
Staphylococcus aureus is an important human pathogen and represents a growing public health burden owing to the emergence and spread of antibiotic-resistant clones, particularly within the hospital...
Feil, Edward J., Li, Bao C., Aanensen, David M., Hanage, William P., Spratt, Brian G.
The introduction of multilocus sequence typing (MLST) for the precise characterization of isolates of bacterial pathogens has had a marked impact on both routine epidemiological surveillance and...
Holden, Matthew T. G., Feil, Edward J., Lindsay, Jodi A., Peacock, Sharon J., Day, Nicholas P. J., Enright, Mark C., ...
Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains, presenting a major...
Evolutionary Genetics of the Accessory Gene Regulator (agr) Locus in Staphylococcus aureus†
Robinson, D. Ashley, Monk, Alastair B., Cooper, Jessica E., Feil, Edward J., Enright, Mark C.
The accessory gene regulator (agr) locus influences the expression of many virulence genes in the human pathogen Staphylococcus aureus. Four allelic groups of agr, which generally inhibit the...
Vesaratchavest, Mongkol, Tumapa, Sarinna, Day, Nicholas P. J., Wuthiekanun, Vanaporn, Chierakul, Wirongrong, Holden, Matthew T. G., ...
Burkholderia pseudomallei is a soil-dwelling saprophyte and the causative agent of melioidosis, a life-threatening human infection. Most cases are reported from northeast Thailand and northern...
Similar compositional biases are caused by very different mutational effects
Rocha, Eduardo P.C., Touchon, Marie, Feil, Edward J.
Compositional replication strand bias, commonly referred to as GC skew, is present in many genomes of prokaryotes, eukaryotes, and viruses. Although cytosine deamination in ssDNA (resulting in C→T...
Thaipadungpanit, Janjira, Wuthiekanun, Vanaporn, Chierakul, Wirongrong, Smythe, Lee D., Petkanchanapong, Wimol, Limpaiboon, Roongrueng, ...
A sustained outbreak of human leptospirosis occurred in northeast Thailand between 1999 and 2003, the basis for which was unknown. Leptospirosis is a potentially serious infection cause by bacteria...
The Persistence of Parasitic Plasmids
Lili, Loukia N., Britton, Nicholas F., Feil, Edward J.
The conditions under which plasmids are predicted to persist remain controversial. Here, we reevaluate the ordinary differential equations used previously to model plasmid persistence and conclude...
Cohen, Ana Luisa V., Oliver, James D., DePaola, Angelo, Feil, Edward J., Fidelma Boyd, E.
Vibrio vulnificus is a ubiquitous inhabitant of the marine coastal environment, and an important pathogen of humans. We characterized a globally distributed sample of environmental isolates from a...
Arvand, Mardjan, Feil, Edward J., Giladi, Michael, Boulouis, Henri-Jean, Viezens, Juliane
Bartonella henselae is a zoonotic pathogen and the causative agent of cat scratch disease and a variety of other disease manifestations in humans. Previous investigations have suggested that a...
Genetic Diversity and Microevolution of Burkholderia pseudomallei in the Environment
Chantratita, Narisara, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, Vesaratchavest, Mongkol, Thanwisai, Aunchalee, Amornchai, Premjit, ...
The soil dwelling Gram-negative bacterium Burkholderia pseudomallei is the cause of melioidosis, a serious human infection that occurs in Southeast Asia and northern Australia. The purpose of this...
Searching for species in haloarchaea
Papke, R. Thane, Zhaxybayeva, Olga, Feil, Edward J., Sommerfeld, Katrin, Muise, Denise, Doolittle, W. Ford
Prokaryotic (bacterial and archaeal) species definitions and the biological concepts that underpin them entail clustering (cohesion) among individuals, in terms of genome content and gene sequence...
Burkholderia pseudomallei genome plasticity associated with genomic island variation
Tumapa, Sarinna, Holden, Matthew TG, Vesaratchavest, Mongkol, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, Chierakul, Wirongrong, ...
Feil, Edward J., Nickerson, Emma K., Chantratita, Narisara, Wuthiekanun, Vanaporn, Srisomang, Pramot, Cousins, Richard, ...
We describe and validate a novel PCR assay to detect the pandemic hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) lineage ST 239. Results based on previously uncharacterized...