Edward R. Block

Luminal flow induces eNOS activation and translocation in the rat thick ascending limb (2003)

Yunchao Su, Sergei I. Zharikov, Edward R. Block, Am J Physiol, Lung Cell, Mol Physiol, ...

doi:10.1152/ajplung.00388.2001 You might find this additional information useful... This article has been cited by 6 other HighWire hosted articles, the first 5 are:

Pharmacological Studies with 5-Fluorocytosine

Block, Edward R., Bennett, John E.

A cylinder plate bioassay for 5-fluorocytosine (5-FC) is described which permits determination of 5-FC concentrations in biological fluids in the presence of amphotericin B. Using this assay, we...

Experimental Therapy of Cladosporiosis and Sporotrichosis with 5-Fluorocytosine

Block, Edward R., Jennings, Anne E., Bennett, John E.

Cladosporium trichoides and Sporothrix schenckii are fungi known to be pathogenic for man. No effective chemotherapy is available for cladosporiosis, and systemic sporotrichosis can be very resistant...

Effect of Hepatic Insufficiency on 5-Fluorocytosine Concentrations in Serum

Block, Edward R.

Hepatic function failed to influence serum concentrations of the antifungal agent 5-fluorocytosine when the drug was given intravenously to rabbits with CCl4-induced hepatic insufficiency or orally...

5-Fluorocytosine Resistance in Cryptococcus neoformans

Block, Edward R., Jennings, Anne E., Bennett, John E.

Isolates of Cryptococcus neoformans from six patients were obtained before and after unsuccessful therapy with 5-fluorocytosine (5-FC). Post-therapy isolates exhibited massive and stable 5-FC...

Variables Influencing Susceptibility Testing of Cryptococcus neoformans to 5-Fluorocytosine

Block, Edward R., Jennings, Anne E., Bennett, John E.

The minimum inhibitory concentration (MIC) of 5-fluorocytosine (5-FC) was determined for 65 isolates of Cryptococcus neoformans by using a twofold serial tube dilution method. The MIC was profoundly...

Stability of Amphotericin B in Infusion Bottles

Block, Edward R., Bennett, John E.

Intravenous solutions of amphotericin B in 5% dextrose water with or without hydrocortisone or heparin demonstrated no appreciable loss of activity when exposed to fluorescent light for up to 24 h at...

5-Fluorocytosine and Amphotericin B in Bronchial Secretions

Pennington, James E., Block, Edward R., Reynolds, Herbert Y.

The penetration into and clearance from bronchial secretions of 5-fluorocytosine and amphotericin B were studied in a dog model. After a single intravenous dose of 35 mg/kg, 5-fluorocytosine...

Pharmacological Studies with 5-Fluorocytosine

Block, Edward R., Bennett, John E.

A cylinder plate bioassay for 5-fluorocytosine (5-FC) is described which permits determination of 5-FC concentrations in biological fluids in the presence of amphotericin B. Using this assay, we...

Experimental Therapy of Cladosporiosis and Sporotrichosis with 5-Fluorocytosine

Block, Edward R., Jennings, Anne E., Bennett, John E.

Cladosporium trichoides and Sporothrix schenckii are fungi known to be pathogenic for man. No effective chemotherapy is available for cladosporiosis, and systemic sporotrichosis can be very resistant...

Effect of Hepatic Insufficiency on 5-Fluorocytosine Concentrations in Serum

Block, Edward R.

Hepatic function failed to influence serum concentrations of the antifungal agent 5-fluorocytosine when the drug was given intravenously to rabbits with CCl4-induced hepatic insufficiency or orally...

5-Fluorocytosine Resistance in Cryptococcus neoformans

Block, Edward R., Jennings, Anne E., Bennett, John E.

Isolates of Cryptococcus neoformans from six patients were obtained before and after unsuccessful therapy with 5-fluorocytosine (5-FC). Post-therapy isolates exhibited massive and stable 5-FC...

Variables Influencing Susceptibility Testing of Cryptococcus neoformans to 5-Fluorocytosine

Block, Edward R., Jennings, Anne E., Bennett, John E.

The minimum inhibitory concentration (MIC) of 5-fluorocytosine (5-FC) was determined for 65 isolates of Cryptococcus neoformans by using a twofold serial tube dilution method. The MIC was profoundly...

Stability of Amphotericin B in Infusion Bottles

Block, Edward R., Bennett, John E.

Intravenous solutions of amphotericin B in 5% dextrose water with or without hydrocortisone or heparin demonstrated no appreciable loss of activity when exposed to fluorescent light for up to 24 h at...

5-Fluorocytosine and Amphotericin B in Bronchial Secretions

Pennington, James E., Block, Edward R., Reynolds, Herbert Y.

The penetration into and clearance from bronchial secretions of 5-fluorocytosine and amphotericin B were studied in a dog model. After a single intravenous dose of 35 mg/kg, 5-fluorocytosine...

Peptides modified by myristoylation activate eNOS in endothelial cells through Akt phosphorylation

Krotova, Karina, Hu, Hanbo, Xia, Shen-Ling, Belayev, Leonid, Patel, Jawaharlal M, Block, Edward R, ...

Myristoylated pseudosubstrate of PKCζ (mPS) – a synthetic myristoylated peptide with a sequence (13 amino acids) mimicking the endogenous PKCζ pseudosubstrate region – is considered a selective...

Involvement of Calpain-Calpastatin in Cigarette Smoke–Induced Inhibition of Lung Endothelial Nitric Oxide Synthase

Cui, Zhaoqiang, Han, Zhaosheng, Li, Zhaozhong, Hu, Hanbo, Patel, Jawaharlal M., Antony, Veena, ...

We reported that cigarette smoke extract (CSE) causes decreases in the activity and expression of endothelial nitric oxide synthase (eNOS) and calpain activity in pulmonary artery endothelial cells...

Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells

Zharikov, Sergey, Krotova, Karina, Hu, Hanbo, Baylis, Chris, Johnson, Richard J., Block, Edward R., ...

Elevated levels of serum uric acid (UA) are commonly associated with primary pulmonary hypertension but have generally not been thought to have any causal role. Recent experimental studies, however,...