Ehmke Pohl

The Metal-Dependent Regulators FurA and FurB from Mycobacterium Tuberculosis (2008)

Debora Lucarelli, Michael L. Vasil, Wolfram Meyer-Klaucke, Ehmke Pohl

The ferric uptake regulators (Fur) form a large family of bacterial metalactivated DNA-binding proteins that control a diverse set of genes at the transcriptional level. Mycobacterium tuberculosis,...

Structural evidence for a proton transfer pathway coupled with haem reduction of cytochrome c '' from Methylophilus methylotrophus (2006)

Enguita, Francisco J., Pohl, Ehmke, Turner, David L., Santos, Helena, Carrondo, Maria Arménia

The crystal structures of the oxidized and reduced forms of cytochrome C '' from Methylophilus methylotrophus were solved from X-ray synchrotron data to atomic resolution. The overall fold of the...

rac-1,1,4-Trimethyl-5-trimethylsilyl-1,3,3a,4,6,7,8,9-octahydro-1-silanaphtho[1,2-c]furan at 153 K (1995)

Pohl, Ehmke, Herbst-Irmer, Regine, Groth, Ulrich, Eckenberg, Peter

The crystal structure of rac-1,1,4-trimethyl-5-trimethylsilyl-1,3,3a,4,6,7,8,9-octahydro-1-silanaphtho[1,2-c]-furan, C17H30OSi2, has been determined at low temperature.

Structure of (±)-1 beta-tert-Butoxy-3a alpha,4 beta,5,6,7,7a-hexahydro-7 a beta-methyl-5-oxo-4 alpha-indancarboxylic Acid Methyl Ester at 153 K (1993)

Pohl, Ehmke, Herbst-Irmer, Regine, Sheldrick, George M., Hommelen, Sieglinde Van, Groth, Ulrich

The X-ray structure of (+)-13-tert-butoxy-3aa,43,5,6,-7,7a-hexahydro-7a3-methyl-5-oxo-4a-indancarboxylic acid methyl ester is reported, in which the six-membered ring adopts a pseudo chair...

Anion-Coordinating Residues at Binding Site 1 Are Essential for the Biological Activity of the Diphtheria Toxin Repressor

Goranson-Siekierke, Joanne, Pohl, Ehmke, Hol, Wim G. J., Holmes, Randall K.

The homodimeric diphtheria toxin repressor (DtxR) uses Fe2+ as a corepressor, binds to iron-regulated promoters, and negatively regulates the syntheses of diphtheria toxin, corynebacterial...

The Three-Dimensional Structure of Cystathionine β-Lyase from Arabidopsis and Its Substrate Specificity

Breitinger, Ulrike, Clausen, Tim, Ehlert, Stephan, Huber, Robert, Laber, Bernd, Schmidt, Frank, ...

The pyridoxal 5′-phosphate-dependent enzyme cystathionine β-lyase (CBL) catalyzes the penultimate step in the de novo biosynthesis of Met in microbes and plants. Absence of CBL in higher organisms...

The Crystal Structure of the Zinc Phosphodiesterase from Escherichia coli Provides Insight into Function and Cooperativity of tRNase Z-Family Proteins

Kostelecky, Brenda, Pohl, Ehmke, Vogel, Andreas, Schilling, Oliver, Meyer-Klaucke, Wolfram

The elaC gene product from Escherichia coli, ZiPD, is a 3′ tRNA-processing endonuclease belonging to the tRNase Z family of enzymes that have been identified in a wide variety of organisms. In...

Anion-Coordinating Residues at Binding Site 1 Are Essential for the Biological Activity of the Diphtheria Toxin Repressor

Goranson-Siekierke, Joanne, Pohl, Ehmke, Hol, Wim G. J., Holmes, Randall K.

The homodimeric diphtheria toxin repressor (DtxR) uses Fe2+ as a corepressor, binds to iron-regulated promoters, and negatively regulates the syntheses of diphtheria toxin, corynebacterial...

The Three-Dimensional Structure of Cystathionine β-Lyase from Arabidopsis and Its Substrate Specificity

Breitinger, Ulrike, Clausen, Tim, Ehlert, Stephan, Huber, Robert, Laber, Bernd, Schmidt, Frank, ...

The pyridoxal 5′-phosphate-dependent enzyme cystathionine β-lyase (CBL) catalyzes the penultimate step in the de novo biosynthesis of Met in microbes and plants. Absence of CBL in higher organisms...

The Crystal Structure of the Zinc Phosphodiesterase from Escherichia coli Provides Insight into Function and Cooperativity of tRNase Z-Family Proteins

Kostelecky, Brenda, Pohl, Ehmke, Vogel, Andreas, Schilling, Oliver, Meyer-Klaucke, Wolfram

The elaC gene product from Escherichia coli, ZiPD, is a 3′ tRNA-processing endonuclease belonging to the tRNase Z family of enzymes that have been identified in a wide variety of organisms. In...

The Metal-Dependent Regulators FurA and FurB from Mycobacterium Tuberculosis

Lucarelli, Debora, Vasil, Michael L., Meyer-Klaucke, Wolfram, Pohl, Ehmke

The ferric uptake regulators (Fur) form a large family of bacterial metal-activated DNA-binding proteins that control a diverse set of genes at the transcriptional level. Mycobacterium tuberculosis,...