Su, Bo, Liu, Haihua, Wang, Xinglong, Chen, Shu G, Siedlak, Sandra L, Kondo, Eisaku, ...
ABSTRACT: Lewy bodies and Lewy neurites constitute the cardinal neuropathological features of both Parkinson's disease (PD) and Lewy body dementia (LBD). Whereas alpha-synuclein has been found to be...
Nanomedicine and drug delivery (2007)
Wei, Chiming, Wei, Wenchi, Morris, Michael, Kondo, Eisaku, Gorbounov, Mikhail, Tomalia, Donald A.
This article discusses the use of nanotechnology is drug delivery approaches. Magnetic nanotechnology is finding wide applications in medicine, most notably in MRI and magnetic separation. The...
Detection of oncogene rearrangements in human non-Hodgkin's lymphomas. (2007)
Kondo, Eisaku, Yoshino, Tadashi, Akagi, Tadaatsu, Hayashi, Kazuhiko, Takahashi, Kiyoshi
Southern blot hybridization was used to detect the rearrangement and amplification of five proto-oncogenes (bcl-2, bcl-1, c-myc, c-myb and c-Ha-ras) and one tumor suppressor gene (RB-1) in 55...
Expression and intracellular localization of FKHRL1 in mammary gland neoplasms. (2006)
Jin, Gui-Shan, Kondo, Eisaku, Miyake, Takayoshi, Shibata, Masao, Takashima, Takako, Liu, Yi-Xuan, ...
FKHRL1 (FOXO3a), a member of the Forkhead family of genes, has been considered to be involved in the development of breast tumors; however, the in vivo expression and activation status of FKHRL1 in...
Ueno, Hiroo, Kondo, Eisaku, Yamamoto-Honda, Ritsuko, Tobe, Kazuyuki, Nakamoto, Tetsuya, Sasaki, Ko, ...
Insulin receptor substrate (IRS) proteins are docking proteins that couple growth factor receptors to various effector molecules, including phosphoinositide-3 kinase, Grb-2, Syp, and Nck. Here we...
Ueno, Hiroo, Kondo, Eisaku, Yamamoto-Honda, Ritsuko, Tobe, Kazuyuki, Nakamoto, Tetsuya, Sasaki, Ko, ...
Insulin receptor substrate (IRS) proteins are docking proteins that couple growth factor receptors to various effector molecules, including phosphoinositide-3 kinase, Grb-2, Syp, and Nck. Here we...
Oka, Takashi, Yoshino, Tadashi, Hayashi, Kazuhiko, Ohara, Nobuya, Nakanishi, Tohru, Yamaai, Yuichiro, ...
To investigate the lymphomagenesis of NK/T lymphoma, we comprehensively and systematically analyzed the expression pattern of the human NK/T cell line (NK-YS) genome by cDNA expression array and...
Hayashi, Kazuhiko, Jin, Zaishun, Onoda, Sachiyo, Joko, Hiromasa, Teramoto, Norihiro, Ohara, Nobuya, ...
Epstein-Barr virus-associated hemophagocytic syndrome (EBV-AHS) is often associated with fatal infectious mononucleosis or T-cell lymphoproliferative diseases (LPD). To elucidate the true nature of...
Hayashi, Kazuhiko, Ohara, Nobuya, Teramoto, Norihiro, Onoda, Sachiyo, Chen, Hong-Li, Oka, Takashi, ...
Epstein-Barr virus-associated hemophagocytic syndrome (EBV-AHS) is often associated with fatal infectious mononucleosis. However, the animal model for EBV-AHS has not been developed. We reported the...
A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus
Glud, Sys Zoffmann, Sørensen, Annette Balle, Andrulis, Mindaugas, Wang, Bruce, Kondo, Eisaku, Jessen, Randi, ...
Nuclear factor of activated T cell (NFAT) transcription factors play a central role in differentiation, activation, and elimination of lymphocytes. We here report on the finding of provirus...
Akimzhanov, Askar, Krenacs, Laszlo, Schlegel, Timm, Klein-Hessling, Stefan, Bagdi, Enikö, Stelkovics, Eva, ...
The nuclear factor of activated T cell 1 (Nfatc1) locus is a common insertion site for murine tumorigenic retroviruses, suggesting a role of transcription factor NFATc1 in lymphomagenesis. Although...
Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease
Su, Bo, Liu, Haihua, Wang, Xinglong, Chen, Shu G, Siedlak, Sandra L, Kondo, Eisaku, ...
Lewy bodies and Lewy neurites constitute the cardinal neuropathological features of both Parkinson's disease (PD) and Lewy body dementia (LBD). Whereas α-synuclein has been found to be the major...