Elisabetta Melloni

Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets

Rocca, Bianca, Secchiero, Paola, Ciabattoni, Giovanni, Ranelletti, Franco O., Catani, Lucia, Guidotti, Lia, ...

Cyclooxygenase (COX)-1 or -2 and prostaglandin (PG) synthases catalyze the formation of various PGs and thromboxane (TX) A2. We have investigated the expression and activity of COX-1 and -2 during...

Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets

Rocca, Bianca, Secchiero, Paola, Ciabattoni, Giovanni, Ranelletti, Franco O., Catani, Lucia, Guidotti, Lia, ...

Cyclooxygenase (COX)-1 or -2 and prostaglandin (PG) synthases catalyze the formation of various PGs and thromboxane (TX) A2. We have investigated the expression and activity of COX-1 and -2 during...

Evidence for a Role of TNF-Related Apoptosis-Inducing Ligand (TRAIL) in the Anemia of Myelodysplastic Syndromes

Campioni, Diana, Secchiero, Paola, Corallini, Federica, Melloni, Elisabetta, Capitani, Silvano, Lanza, Francesco, ...

Myelodysplastic syndromes (MDS) are characterized by impaired erythropoiesis, possibly caused by proapoptotic cytokines. We focused our study on the cytokine TRAIL (TNF-related apoptosis-inducing...

The MDM-2 Antagonist Nutlin-3 Promotes the Maturation of Acute Myeloid Leukemic Blasts1

Secchiero, Paola, Zerbinati, Carlotta, Melloni, Elisabetta, Milani, Daniela, Campioni, Diana, Fadda, Roberto, ...

The small-molecule inhibitor of murine double minute (MDM-2), Nutlin-3, induced variable apoptosis in primary acute myeloid leukemia (AML) blasts and promoted myeloid maturation of surviving cells,...

Human Bone Marrow Mesenchymal Stem Cells Display Anti-Cancer Activity in SCID Mice Bearing Disseminated Non-Hodgkin's Lymphoma Xenografts

Secchiero, Paola, Zorzet, Sonia, Tripodo, Claudio, Corallini, Federica, Melloni, Elisabetta, Caruso, Lorenzo, ...