Elise C. Kohn

Proteomics in Clinical Trials and Practice PRESENT USES AND FUTURE PROMISE* (2008)

Nilofer S. Azad, Nabila Rasool, Christina M. Annunziata, Lori Minasian, Gordon Whiteley, Elise C. Kohn

The study of clinical proteomics is a promising new field that has the potential to have many applications, including the identification of biomarkers and monitoring of disease, especially in the...

MECHANISMS OF DISEASE Mechanisms of disease Use of proteomic patterns in serum to identify ovarian cancer (2008)

Ali M Ardekani, Ben A Hitt, Peter J Levine, Vincent A Fusaro, Seth M Steinberg, ...

Background New technologies for the detection of earlystage ovarian cancer are urgently needed. Pathological changes within an organ might be reflected in proteomic patterns in serum. We developed a...

BRIEF COMMUNICATIONS Serum Proteomic Patterns for Detection of Prostate Cancer (2008)

David K, Cloud P. Paweletz, Paul S. Hackett, Ben A, Alfredo Velassco, ...

Pathologic states within the prostate may be reflected by changes in serum proteomic patterns. To test this hypothesis, we analyzed serum proteomic mass spectra with a bioinformatics tool to reveal...

The alarm anti-protease, secretory leukocyte protease inhibitor, is a proliferation and survival factor for ovarian cancer cells (2008)

Simpkins, Fiona A., Devoogdt, Nick M., Rasool, Nabila, Tchabo, Nana E., Alejandro, Emilyn U., ...

Alarm anti-proteases are secreted locally in response to inflammation and have been shown to be elevated in cancers. Secretory leukocyte protease inhibitor (SLPI), an alarm anti-protease, is...

Serum Proteomic Patterns for Detection of Prostate Cancer (2002)

Petricoin, Emanuel F., Ornstein, David K., Paweletz, Cloud P., Ardekani, Ali, Hackett, Paul S., Hitt, Ben A., ...

Pathologic states within the prostate may be reflected by changes in serum proteomic patterns. To test this hypothesis, we analyzed serum proteomic mass spectra with a bioinformatics tool to reveal...

Dose-Intense Taxol: High Response Rate in Patients With Platinum-Resistant Recurrent Ovarian Cancer (1994)

Kohn, Elise C., Sarosy, Gisele, Bicher, Annette, Link, Charles, Christian, Michaele, Steinberg, Seth M., ...

Background Paclitaxel (Taxol), a diterpene plant product that promotes tubulin polymerization, has documented activity against a number of solid tumors, including ovarian cancer and breast cancer...